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Abstract

Background: Osteomyelitis is an acute or chronic inflammatory process of the bone following infection with pyogenic organisms like Staphylococcus aureus. Tobramycin (TOB) is a promising aminoglycoside antibiotic used to treat various bacterial infections, including S. aureus. The aim of this study...

Author(s)
Godday Anebow Lulu; Arunkumar Karunanidhi; Loqman Mohamad Yusof; Yusuf Abba; Fazlin Mohd Fauzi; Fauziah Othman
Publisher
BioMed Central Ltd, London, UK
Citation
Annals of Clinical Microbiology and Antimicrobials, 2018, 17, 46, pp (28 December 2018)
Abstract

This study was conducted to investigate the beneficial effects of chitosan in the immunopathology of osteomyelitis in diabetic rabbits; therefore, the experimental design was carried out on 40 rabbits. They were divided into 5 groups each of 8 animals, diabetes mellitus was induced in rabbits, then ...

Author(s)
Maktoof, Z. A.; Ahmed, J. A.
Publisher
University of Basrah, Basrah, Iraq
Citation
Basrah Journal of Veterinary Research, 2018, 17, 2, pp 51-69
Abstract

Candida osteomyelitis is a debilitating disease that is difficult to diagnose and treat. As there are no animal models or prospective studies for this uncommon infection, little is known about the pathogenesis, diagnosis, or treatment. We therefore sought to establish an animal model for the study...

Author(s)
Gamaletsou, M. N.; Meletiadis, J.; Chatziioannou, S.; Panayiotides, I. G.; Agadakos, E.; Katsimpoulas, M.; Kostomitsopoulos, N.; Petraitis, V.; Walsh, T. J.; Sipsas, N. V.
Publisher
Oxford University Press, Oxford, UK
Citation
Medical Mycology, 2019, 57, 8, pp 1011-1017
Abstract

Objective: To investigate the effects of Kanggu Suiyan Tablet (KST) against osteomyelitis in rabbits. Methods: Osteomyelitis model of rabbits were prepared by intra-shinbone marrow injection of Staphylococcus aureus. Model rabbits were divided at random into four groups, i.e., model (equal volume...

Author(s)
Zhang HongGuo; Wu Fang; Liu ChunMei; Cao JunPing
Publisher
Drug Evaluation Research, Tianjin, China
Citation
Drug Evaluation Research, 2018, 41, 8, pp 1441-1445
Abstract

CASE DESCRIPTION: A 16-month-old neutered male Continental Giant rabbit (Lepus curpaeums) was referred for evaluation of a 7-day history of acute-onset, progressive, symmetric paraparesis. CLINICAL FINDINGS: On initial examination, the rabbit was nonambulatory, and results of neurologic examination ...

Author(s)
Crawford, A. H.; Hedley, J. E.; Lam, R.; Drożdżyńska, M. J.; Decker, S. de
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
Journal of the American Veterinary Medical Association, 2017, 251, 3, pp 340-344
Abstract

The purpose of this paper is to present a radiological assessment of the treatment performed on a model of human osteomyelitis induced in rabbits. In order to induce osteomyelitis in rabbits, a human strain of Staphylococcus aureus was injected in bone defects created in the rabbit tibia, a...

Author(s)
Coman, C.; Surdu-Bob, C. C.; Gonciarov, M.; Vlase, E.; Badulescu, M.
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Agriculture and Agricultural Science Procedia, 2015, 6, pp 299-304
Abstract

Objectives: In a new experimental model of carbapenemase-producing Klebsiella pneumoniae osteomyelitis we evaluated the efficacy of colistin alone and in various combinations and examined the emergence of colistin-resistant strains and cross-resistance to host defence peptides (HDPs). Methods:...

Author(s)
Crémieux, A. C.; Dinh, A.; Nordmann, P.; Mouton, W.; Tattevin, P.; Ghout, I.; Jayol, A.; Aimer, O.; Gatin, L.; Verdier, M. C.; Saleh-Mghir, A.; Laurent, F.
Publisher
Oxford University Press, Oxford, UK
Citation
Journal of Antimicrobial Chemotherapy, 2019, 74, 9, pp 2666-2675
Abstract

Objective: We investigated the benefits of a local preventive therapy based on copper beads against severe bone infection using a rabbit open tibial fracture model. Materials and Methods: Cotton mesh balls soaked in a very high concentration of Staphylococcus aureus ATCC 6538 culture were...

Author(s)
Surdu-Bob, C. C.; Vlase, E.; Barbuceanu, F.; Turcu, D.; Coman, M.; Badulescu, M.; Oporanu, M.; Coman, C.
Publisher
Georg Thieme Verlag KG, Stuttgart, Germany
Citation
Veterinary and Comparative Orthopaedics and Traumatology, 2019, 32, 1, pp 41-50
Abstract

Propionibacterium acnes and coagulase-negative staphylococci (CoNS) are opportunistic pathogens implicated in prosthetic joint and fracture fixation device-related infections. The purpose of this study was to determine whether P. acnes and the CoNS species Staphylococcus lugdunensis, isolated from...

Author(s)
Gahukamble, A. D.; McDowell, A.; Post, V.; Varela, J. S.; Rochford, E. T. J.; Richards, R. G.; Patrick, S.; Moriarty, T. F.
Publisher
American Society for Microbiology (ASM), Washington, USA
Citation
Journal of Clinical Microbiology, 2014, 52, 5, pp 1595-1606
Abstract

Prosthetic joint infections are difficult to diagnose and treat due to biofilm formation by the causative pathogens. Pathogen identification relies on microbial culture that requires days to weeks, and in the case of chronic biofilm infections, lacks sensitivity. Diagnosis of infection is often...

Author(s)
Harro, J. M.; Shirtliff, M. E.; Arnold, W.; Kofonow, J. M.; Dammling, C.; Achermann, Y.; Brao, K.; Parvizi, J.; Leid, J. G.
Publisher
American Society for Microbiology (ASM), Washington, D.C., USA
Citation
Journal of Clinical Microbiology, 2020, 58, 5,

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