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The present study was aimed to evaluate the effects of topical 1% nalbuphine on corneal sensitivity and re-epithelialization, after lamellar keratectomy in rabbits. All protocols were approved by the Animal Care Comission of São Paulo State University (Protocol 028793-08) and were conducted in...
The analgesic actions of buprenorphine, butorphanol, nalbuphine and pentazocine were assessed in the rabbit (n=20) by analgesiometry using a thermal stimulus. All four compounds produced effective analgesia without causing serious respiratory depression. Increased dose rates of buprenorphine,...