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Abstract

PICO question: In domestic rabbits, how does 1 mg/kg of oral meloxicam compare with 0.2 mg/kg of oral meloxicam for significant changes in pain behaviour, and kidney and liver biochemical analytes? Clinical bottom line: Based on current available evidence, oral meloxicam at a dosage of 0.2 mg/kg...

Author(s)
Nield, K.; Govendir, M.
Publisher
RCVS Knowledge, London, UK
Citation
Veterinary Evidence, 2019, 4, 2,
Abstract

Objective - To determine the pharmacokinetics of meloxicam (1 mg/kg) in rabbits after oral administration of single and multiple doses. Animals - 6 healthy rabbits. Procedures - A single dose of meloxicam (1 mg/kg, PO) was administered to the rabbits. After a 10-day washout period, meloxicam (1...

Author(s)
Fredholm, D. V.; Carpenter, J. W.; KuKanich, B.; Kohles, M.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2013, 74, 4, pp 636-641
Abstract

Objective - To determine the pharmacokinetics and safety of meloxicam in rabbits when administered orally for 29 days. Animals - 6 healthy rabbits. Procedures - Meloxicam (1.0 mg/kg, PO, q 24 h) was administered to rabbits for 29 days. Blood was collected immediately before (time 0) and 2, 4, 6, 8, ...

Author(s)
Delk, K. W.; Carpenter, J. W.; KuKanich, B.; Nietfeld, J. C.; Kohles, M.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2014, 75, 2, pp 195-199
Abstract

Grapiprant is the novel selective EP4 receptor inhibitor recently issued on the veterinary market for dogs affected by osteoarthritis. The aim of this study was twofold: to evaluate the pharmacokinetics and the pharmacodynamics of grapiprant in the induced inflammatory pain model in the rabbit...

Author(s)
Vito, V. de; Salvadori, M.; Poapolathep, A.; Owen, H.; Rychshanova, R.; Giorgi, M.
Publisher
Wiley, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2017, 40, 5, pp 468-475
Abstract

A 4-year-old castrated male lop-eared rabbit (Oryctolagus cuniculus) presented for right thoracic limb weakness of 1 week duration. Radiographs of the limb and adjacent spine were unremarkable. Despite treatment with meloxicam, limb weakness slowly progressed. Four months after initial...

Author(s)
Stern, H.; Guzman, D. S. M.; Gleeson, M.; Ozawa, S.; Liepnieks, M. L.; McLarty, E.; Johnson, E.; Niederhuth, J. H.
Publisher
Elsevier, New York, USA
Citation
Journal of Exotic Pet Medicine, 2019, 31, pp 75-78
Abstract

Calvarial bone surgery on rabbits is frequently performed. This report aims to document a simple and practical anaesthetic and perioperative management for this procedure. Fourteen male New Zealand white rabbits were included in the study. Subcutaneous (SC) dexmedetomidine, ketamine and...

Author(s)
Raillard, M.; Detotto, C.; Grepper, S.; Beslac, O.; Fujioka-Kobayashi, M.; Schaller, B.; Saulacic, N.
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2019, 9, 11, pp 896
Abstract

Despite the increasing use of rabbits as companion animals and models for biomedical research, rabbits have not been extensively studied to identify an efficacious postsurgical analgesic that does not cause systemic complications. The synergy of NSAID and systemic opioids is well-documented, and...

Author(s)
Goldschlager, G. B.; Gillespie, V. L.; Palme, R.; Baxter, M. G.
Publisher
American Association for Laboratory Animal Science, Memphis, USA
Citation
Journal of the American Association for Laboratory Animal Science, 2013, 52, 5, pp 571-576
Abstract

A healthy 2-year-old entire female domestic dwarf rabbit (Oryctolagus cuniculus) was referred for ovariohysterectomy. The premedication included subcutaneous 3 mg/kg ketamine, 1 mg/kg midazolam and 0.05 mg/kg medetomidine. A CT scan was performed under sedation to assess the lumbosacral region....

Author(s)
Serra, R. M.; Dominguez, S.; Vilalta, L.; Palacios, C.
Publisher
BMJ Publishing Group, London, UK
Citation
Veterinary Record Case Reports, 2020, 8, 2,
AbstractFull Text

Aim: Evaluation of meloxicam, levofloxacin, pazufloxacin, and enrofloxacin for their effect on the plasma antioxidative activity (AOA) and the body weight in rabbits. Materials and Methods: Thirty two male Soviet Chinchilla rabbits were divided to eight groups of four rabbits each. Group A, serving ...

Author(s)
Khan, A. M.; Satyavan Rampal
Publisher
Veterinary World, Rajkot, India
Citation
Veterinary World, 2013, 6, 12, pp 950-954
Abstract

Prolonged antibiotic and antiinflammatory therapy for complicated infections exposes the body to xenobiotics that can produce several adverse effects for which oxidative damage is the proposed underlying mechanism. In this context, we evaluated the effect of pazufloxacin, a fluoroquinolone...

Author(s)
Khan, A. M.; Satyavan Rampal
Publisher
American Association for Laboratory Animal Science, Memphis, USA
Citation
Journal of the American Association for Laboratory Animal Science, 2014, 53, 4, pp 399-403

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