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VetMed Resource

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Abstract

Flumazenil, a competitive GABAA receptor antagonist, is commonly used in rabbits to shorten sedation or postanesthetic recovery after benzodiazepine administration. However, no combined pharmacokinetic (PK) and pharmacodynamic (PD) data are available to guide its administration in this species. In...

Author(s)
Rousseau-Blass, F.; Cribb, A. E.; Beaudry, F.; Pang, D. S.
Publisher
American Association for Laboratory Animal Science, Memphis, USA
Citation
Journal of the American Association for Laboratory Animal Science, 2021, 60, 3, pp 319-328
Abstract

Rabbits are a common companion animal and research subject and frequently require sedation to facilitate procedures. The objective of this study was to compare the effects of intramuscular butorphanol and midazolam combined with either alfaxalone or ketamine in rabbits. In a complete crossover...

Author(s)
Knutson, K. A.; Petritz, O. A.; Thomson, A. E.; Balko, J. A.
Publisher
American Association for Laboratory Animal Science, Memphis, USA
Citation
Journal of the American Association for Laboratory Animal Science, 2022, 61, 5, pp 475-481
Abstract

The objective of this study was to investigate the short-term cardiovascular effects of intravenous (IV) medetomidine-midazolam-fentanyl (MMF) injections in the rabbit using vascular ultrasonography and echocardiography. Anesthesia with MMF was induced intramuscularly (IM) in 8 female New Zealand...

Author(s)
Baumgartner, C.; Bollerhey, M.; Ebner, J.; Schuster, T.; Henke, J.; Erhardt, W.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Journal of Veterinary Research, 2010, 74, 4, pp 286-298
Abstract

Unbound fractions of 14C-labelled diazepam and tenoxicam in skim milk of various species (man, mare, goat, cow, ewe, dog, rabbit) with different milk compositions were determined. Furthermore, the protein binding of 5 14C-labelled benzodiazepines differing in their lipophilicity (bromazepam,...

Author(s)
Stebler, T.; Guentert, T. W.
Citation
Pharmaceutical Research, 1990, 7, 6, pp 633-637

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