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AbstractFull Text

Background: The glaucoma is a progressive optical neuropathy generally associated to the increase of the intraocular pressure (IOP). It is a disease of difficult therapeutic conduct and potential cause of blindness. The dorzolamide at 2% and the latanoprost at 0.005% are topical antiglaucoma drugs...

Author(s)
Barbosa, E. B.; Silva Junior, P. G. P. da; Melo, M. M.
Publisher
Universidade Federal do Rio Grande do Sul, Faculdade de Veterinária, Porto Alegre, Brazil
Citation
Acta Scientiae Veterinariae, 2020, 48, 1775,
Abstract

Background: Rabbits are currently not a good model for studying diseases of the corneal endothelium because their corneal endothelial cells (CECs) maintain a high proliferative capacity throughout almost all their life. Addressing this particular feature might allow the use of this species for such ...

Author(s)
Segarra, S.; Leiva, M.; Costa, D.; Coyo, N.; Sabés-Alsina, M.; Ríos, J.; Peña, T.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2018, 14, 39, pp (2 February 2018)
Abstract

Listeria monocytogenes is a foodborne pathogen adapted to survive and persist in multiple environments. Following two previous studies on prevalence and virulence of L. monocytogenes ST121 and ST14 repeatedly collected in a the same rabbit-meat processing plant, the research questions of the...

Author(s)
Pasquali, F.; Palma, F.; Guillier, L.; Lucchi, A.; Cesare, A. de; Manfreda, G.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Microbiology, 2018, 9, March, pp 596
Abstract

PURPOSE. To establish a rabbit dry eye model with topical medication of the ocular preparation preservative benzalkonium chloride (BAC). METHODS. Sixteen white rabbits were used. One eye of each rabbit was chosen randomly for topical administration of 0.1% BAC twice daily for 14 days. The other...

Author(s)
Xiong CuiJu; Chen Dong; Liu JingBo; Liu BingQian; Li NaiYang; Zhou Yang; Liang XuanWei; Ma Ping; Ye ChengTian; Ge Jian; Wang ZhiChong
Publisher
Association for Research in Vision and Ophthalmology, Inc., Rockville, USA
Citation
Investigative Ophthalmology & Visual Science, 2008, 49, 5, pp 1850-1856
Abstract

The prediction of side-effects is a key issue in the REACH initiative on chemicals, in the production of cosmetics and in the preclinical testing of drugs. A new ex vivo test for repeated substance application is presented, that is able to identify corrosive and irritant effects on the eye by using ...

Author(s)
Frentz, M.; Goss, M.; Reim, M.; Schrage, N. F.
Publisher
Fund for the Replacement of Animals in Medical Experiments, Nottingham, UK
Citation
ATLA, Alternatives to Laboratory Animals, 2008, 36, 1, pp 25-32
Abstract

The effects of olive oil and flax seed oil on the tear film structure in rabbits induced with dry eye condition were monitored after 4 and 8 days of application. The tear film analysis was accomplished using Fourier transform infrared spectroscopy. The dry eye induced by 0.1% benzalkonium chloride, ...

Author(s)
Khalil, A.; Aly, M. A.; Sherif, S. M.; Taalat, M. S.; Sallam, A. M.
Publisher
Editura Academiei Romane, Bucaresti, Romania
Citation
Romanian Journal of Biophysics, 2014, 24, 1, pp 55-64
Abstract

Inhibiting the healing of wounds to ensure that the aqueous humor can drain into the scleral space unimpeded and form a filtering bleb plays a crucial role in determining the success rate of glaucoma surgery. The aim of this study was to investigate the novel use, with cell culture and animal...

Author(s)
Wu KwouYeung; Wu PeiCheng; Lai YuHung; Hong ShowJen
Publisher
Elsevier (Singapore) Pte Ltd, Hong Kong, China
Citation
Kaohsiung Journal of Medical Sciences, 2013, 29, 7, pp 353-361
Abstract

Evaluation of the eye irritation is essential in the development of new cosmetic products. Draize rabbit eye irritation test has been widely used in which chemicals are directly applied to rabbit eye, and the symptoms and signs of eyes are scored. However, due to the invasive procedure, it causes...

Author(s)
Choi SeungHye; Lee MiRi; Lee SuHyon; Jung HaengSun; Kim SeolYeong; Chung TaeYoung; Choe TaeBoo; Chun YoungJin; Lim KyungMin
Publisher
Springer Berlin, Heidelberg, Germany
Citation
Archives of Toxicology, 2015, 89, 9, pp 1589-1598
Abstract

Purpose: The objective of this study was to determine the ocular bioavailability of hesperidin and hesperetin, especially with respect to their distribution into the posterior segment of the eye, following systemic and topical administration in rabbits. Methods: Hesperidin and hesperetin were...

Author(s)
Srirangam, R.; Hippalgaonkar, K.; Avula, B.; Khan, I. A.; Majumdar, S.
Publisher
Mary Ann Liebert, Inc., New Rochelle, USA
Citation
Journal of Ocular Pharmacology and Therapeutics, 2012, 28, 6, pp 618-627
Abstract

Studies were conducted to investigate the haemostatic, antiinflammatory, antibacterial and healing promotion of Bletilla striata. The cutting-tail method and femoral artery haemostasis were conducted to study the haemostasis effect and ear swelling induced by dimethylbenzene, antiinflammation and...

Author(s)
Zhang PengWei; Li HaiLong; Tan YinFeng; Su WenQin; Zhang JunQing; Fan Kai; Liu MingSheng
Publisher
Editorial Board of Journal of Hainan Medical College, Haikou, China
Citation
Journal of Hainan Medical College, 2011, 17, 1, pp 21-23, 30

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