Mebendazole (MBZ), a synthetic benzimidazole, is most widely used for the treatment of intestinal helminthiasis. In the present study, a hapten mimicking the MBZ structure was designed by introducing propanoic acid and coupling to carrier proteins by the active ester method to immunize New Zealand ...

To treat encephalitozoonosis effectively, the drug, albendazole was chosen at this experiment according to biological characters of parasites and tissue lesions caused by Encephalitozoon cuniculi. Twenty eight recessive infectious rex rabbits (3-4 months old) were divided into control group and...

An HPLC/MS/MS method was developed for the simultaneous determination of the following benzimidazole anthelmintics and metabolites in plasma: flubendazole, albendazole, fenbendazole, mebendazole, thiabendazole, hydrolyzed flubendazole, albendazole sulfoxide, albendazole sulfone, albendazole...

Two 10 months old male mixed bred rabbits were presented with abnormal masses within their right eyes. Ocular examination revealed anterior uveitis, abscess-like masses at the iris and incipient cataract. Albendazole and anti-inflammatory medication were prescribed. Phacoemulsification was...

Secondary hydatidosis is an important problem encountered during the surgical treatment of hydatid cysts. This study describes an experimental model of secondary hydatidosis by cyst inoculation, used to explore whether simultaneous inoculation of protoscolocidal agents could prevent secondary...

Objectives: To determine the effects of albendazole on rabbits infected with larvae of Angiostrongylus cantonensis by histopathological and magnetic resonance imaging (MRI) techniques. Methods: Male rabbits were infected with 400 A. cantonensis larvae and treated with albendazole (5 mg/kg/day) for...

This article discusses the disease prevalence, pathogenesis, clinical aspects, diagnosis, treatment (benzimidazole, fenbendazole, albendazole, oxibendazole, corticosteroids and glucocorticoids), disease control and preventive programmes against Encephalitozoon cuniculi in rabbits from UK.

Three groups of rabbits were used in the study: rabbits experimentally infected with E. cuniculi spores (group A), rabbits infected with E. cuniculi but simultaneously treated with albendazole (group B), and control (group C). The development of immune response was examined by indirect...

The oral bioavailability of granules of albendazole prepared by the solid dispersion technique was investigated. Rapid dissolution and supersaturation were observed when hydroxypropylmethylcellulose and hydroxypropylmethylcellulose phthalate were used as carriers in the solid dispersion. They...