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Abstract

Oclacitinib (OCL) is a novel immunosuppressive agent approved for dogs that controls itch and inflammation in allergic disease via the inhibition of the JAK/STAT pathway. This paper investigates the in vitro effect of OCL, a novel Janus kinase inhibitor, on selected canine regulatory (Treg) and...

Author(s)
Jasiecka-Mikołajczyk, A.; Jaroszewski, J. J.; Maślanka, T.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2018, 121, pp 124-129
Abstract

Canine atopic dermatitis (CAD) is a chronic, pruritic, genetic, and inflammatory disease. Its pathogenesis is very complex and involves skin barrier defects and immune system dysfunction. This study aimed to investigate hematological, biochemical, clinical, and immunological parameters to...

Author(s)
Martins, G. de C.; Melo Júnior, O. A. de O.; Botoni, L. S.; Nogueira, M. M.; Val, A. P. da C.; Blanco, B. S.; Dutra, W. O.; Giunchetti, R. C.; Melo, M. M.; Lemos, D. da S.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2018, 205, pp 58-64
Abstract

Background: As prednisone and ciclosporin can have immunosuppressive effects and have been considered potential predisposing factors for skin infections, we investigated the impact of these drugs on the diversity of the cutaneous microbiota, the abundance of Malassezia and infection with ...

Author(s)
Widmer, G.; Ferrer, L.; Favrot, C.; Paps, J.; Huynh, K.; Olivry, T.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2018, 14, 51, pp (23 February 2018)
Abstract

The aim of this study was to demonstrate whether there is a correlation between transepidermal water loss (TEWL) and the severity of skin lesions in cats with feline atopic dermatitis (AD). The severity of symptoms was determined by using 2 scoring systems for clinically assessing the skin lesions...

Author(s)
Szczepanik, M. P.; Wilkołek, P. M.; Adamek, Ł. R.; Kalisz, G.; Gołyński, M.; Sitkowski, W.; Taszkun, I.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Journal of Veterinary Research, 2018, 82, 4, pp 306-311
Abstract

Background: For decades, the efficacy of interventions in clinical trials enrolling dogs with atopic dermatitis (AD) relied on heterogeneous evaluations of skin lesions and pruritus using unvalidated tools. Although some instruments for clinical signs were validated later, there was little impact...

Author(s)
Olivry, T.; Bensignor, E.; Favrot, C.; Griffin, C. E.; Hill, P. B.; Mueller, R. S.; Plant, J. D.; Williams, H. C.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2018, 14, 238, pp (16 August 2018)
Abstract

Background: Corn appears to be an uncommon food source of allergens in dogs and cats. There is limited information on the nature of the corn allergens in dogs and cats and their presence in the various foodstuffs used in commercial pet foods. The aim of this study was to determine if serum IgE from ...

Author(s)
Olivry, T.; Bexley, J.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2018, 14, 207, pp (27 June 2018)
Abstract

Background: An investigation was conducted in West Central Florida, USA to evaluate the efficacy of either topically applied fluralaner or topically applied selamectin to control flea infestations, minimize dermatologic lesions and reduce pruritus in naturally flea infested cats over a 12-week...

Author(s)
Dryden, M. W.; Canfield, M. S.; Bocon, C.; Phan, L.; Niedfeldt, E.; Kinnon, A.; Warcholek, S. A.; Smith, V.; Bress, T. S.; Smith, N.; Heaney, K.; Royal, C.; Normile, D.; Armstrong, R.; Sun FangShi
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2018, 11, 422, pp (16 July 2018)
Abstract

Background: Lotilaner is a new isoxazoline developed as an oral ectoparasiticide for cats and dogs. Its safety, rapid killing onset of action and sustained speed of fleas and ticks kill for a minimum of one month after administration, were demonstrated in a number of laboratory studies in cats....

Author(s)
Cavalleri, D.; Murphy, M.; Seewald, W.; Nanchen, S.
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2018, 11, 410, pp (13 July 2018)
AbstractFull Text

Canine atopic dermatitis (CAD) is a common skin disease and numerous factors participate in forming clinical features of this disease. Intradermal tests (IDT) enabled determination of allergen(s) involved in CAD. Allergens that can be related with CAD are numerous and depend on geographical region. ...

Author(s)
Babić, S.; Pašić, Š.; Zahirović, A.
Publisher
Veterinarski Fakultet Univerziteta u Sarajevu, Sarajevo, Bosnia-Herzegovina
Citation
Veterinaria (Sarajevo), 2018, 67, 3, pp 139-144
Abstract

Atopic dermatitis (AD) with itching and inflammation is the most common skin allergy in dogs. We describe a mice model for AD. Three groups of 3 C57B1/6 mice were infested twice on skin with a dressing embedded with 0.1 ml extract of Dermatophagoides farinae mites in 2, 3 or 4 cycles. Mice were...

Author(s)
Borges, T. de C.; Silva, C. F. A.; Silva, P. H. de S. da; Castro, M. B. de; Vianna, A. R. da C. B.; Lima, E. M. M. de
Publisher
Online Journal of Veterinary Research, Toowoomba, Australia
Citation
Online Journal of Veterinary Research, 2018, 22, 9, pp 799-805

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