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AbstractFull Text

Despite the pivotal role of α2-agonists for standing sedation in horses, these drugs possess several dose-dependent side effects. Therefore, this study aimed to determine the effect of nalbuphine or ketamine on xylazine requirements necessary to provide constantly moderate sedation in horses. Five...

Author(s)
Sharshar, A.; Hammad, A.; Gadallah, S.; Thabet, N.; Misk, T.
Publisher
Veterinarski Fakultet Sveučilišta u Zagrebu (Faculty of Veterinary Medicine, University of Zagreb), Zagreb, Croatia
Citation
Veterinarski Arhiv, 2022, 92, 4, pp 369-380
Abstract

Objective: To determine the effect of xylazine on intracranial pressure (ICP) in standing compared to isoflurane-anesthetized horses. Design: Prospective, crossover study design. Setting: University Teaching Hospital. Animals: Six adult horses donated to the University. Horses were determined to be ...

Author(s)
Reed, R. A.; Epstein, K. L.; Bramski, J. H.; Diehl, K. A.; Ryan, C. A.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Emergency and Critical Care, 2021, 31, 4, pp 476-482
Abstract

This randomized double-blinded study evaluated the recovery from isoflurane anesthesia in horses receiving doxapram and xylazine. 6 horses were anesthetized 4 times (minimum of 2-week washout period). Anesthesia was performed with xylazine (0.6 mg/kg), ketamine (2.2 mg/kg), midazolam (0.1 mg/kg),...

Author(s)
Midon, M.; Yamada, D. I.; Filho, D. Z.; Natalini, C. C.; Escobar, A.; Clark-Price, S. C.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2022, 111,
Abstract

In veterinary medicine, a number of alpha-2 receptor agonists are marketed as sedatives/hypnotics and analgesics, with their principal use being the chemical restraint of large and small animals. Guanabenz (Wytensin®) is an alpha-2 adrenergic receptor agonist marketed for use in humans as an...

Author(s)
Lehner, A. F.; Dirikolu, L.; Tabin, T.
Publisher
Hippiatrika Verlag GmbH, Baden-Baden, Germany
Citation
Pferdeheilkunde, 2022, 38, 6, pp 554-565
Abstract

Xylazine and remifentanil in constant rate infusion (CRI) could be used for sedation in horses without adverse effects. The objective was to evaluate behavioral and cardiopulmonary effects of an intravenous (IV) infusion of xylazine and remifentanil for sedation in horses. Xylazine (0.8 mg/kg IV)...

Author(s)
Pallarols, N. B.; Lamuraglia, R.; Guglielminetti, A.; Ortiz Elguea, M. F. de; Carossino, M.; Funcia, J. P.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2020, 91,
Abstract

The aim of this study was to evaluate the effects of xylazine and acepromazine on the Doppler and M-mode echocardiography measurements in horses. Ten healthy crossbred horses were included in this study. Baseline echocardiography was performed in all horses. Xylazine (0.5 mg/kg IV) or acepromazine...

Author(s)
Dezfouli, M. R. M.; Tavanaeimanesh, H.; Houshangi, A. F.; Corley, K.; Masoudifard, M.; Chaleshtori, S. S.; Dalir-Naghadeh, B.
Publisher
Hippiatrika Verlag GmbH, Baden-Baden, Germany
Citation
Pferdeheilkunde, 2020, 36, 1, pp 37-42
Abstract

Introduction: To assess drug plasma levels, preanesthetic sedation, cardiopulmonary effects during anesthesia and recovery in horses anesthetized with isoflurane combined with medetomidine or xylazine. Study design: Prospective blinded randomized clinical study. Animals: Sixty horses undergoing...

Author(s)
Wiederkehr, A.; Barbarossa, A.; Ringer, S. K.; Jörger, F. B.; Bryner, M.; Bettschart-Wolfensberger, R.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2021, 7, April,
Abstract

This study determined the pharmacokinetics and compared the clinical effects of xylazine and dexmedetomidine in horses recovering from isoflurane anesthesia. Six healthy horses aged 8.5 ± 3 years and weighing 462 ± 50 kg were anesthetized with isoflurane for 2 hr under standard conditions on two...

Author(s)
Guedes, A.; Knych, H.; Tucker, L.; Almeida, D. C.; Baldo, C. F.; Wendt-Hornickle, E.; Allweiler, S.
Publisher
Wiley, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2020, 43, 4, pp 369-376
Abstract

Medetomidine partial intravenous anaesthesia (PIVA) has not been compared to xylazine PIVA regarding quality of recovery. This clinical retrospective study compared recoveries following isoflurane anaesthesia balanced with medetomidine or xylazine. The following standard protocol was used: sedation ...

Author(s)
Kälin, I.; Henze, I. S.; Ringer, S. K.; Torgerson, P. R.; Bettschart-Wolfensberger, R.
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2021, 11, 8,
Abstract

The purpose of this prospective, blinded, randomized clinical trial was to compare the effects of low dose detomidine to xylazine on recovery quality and duration in a castration procedure. Horses were administered either detomidine [0.015 mg/kg body weight (BW)] or xylazine (1.1 mg/kg BW)...

Author(s)
Jarosinski, S. K.; Simon, B. T.; Hatfield, R.; Matthews, N. S.; Arnold, C. E.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Veterinary Journal, 2021, 62, 9, pp 982-986

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