Whereas the etiology of equine recurrent uveitis (ERU), concerning the typical clinical form of the disease, was found to be a persistent intraocular leptospiral infection, the pathomechanisms during and between the recurrent bouts of intraocular inflammation are still unknown. In the present study ...

Ocular setarial worms (19) were removed surgically from 17 horses (18 eyes). In 16 cases with the worm in anterior chamber (AC), paracentesis was performed through modified clear corneal stab incision using a 2.8 mm keratome. In one case of worm in vitreous, paracentesis was performed through pars...

One hundred and sixty horses with different conditions underwent ophthalmic and ocular ultrasound examinations, and the concordance of the results was evaluated. Specificity, sensitivity, positive and negative predictive values, and the associated 95% confidence interval were calculated. The k...

Among the main causes of damages to equideoculture are the various diseases, among them ocular diseases, especially keratitis and uveitis. These have an inflammatory origin and are associated with the main cases of blindness in horses. Uveitis is by definition the inflammation of the uveal tract of ...

In Germany, the surgical removal of as much vitreous as possible (vitrectomy) is a common treatment of equine recurrent uveitis (ERU). Intraocular leptospiral infection has been found to be the reason for an immune-mediated reaction which finally causes the typical signs of ERU. Inflammatory...

Cyclosporine A (CsA) is a potent immunosuppressive drug which is used in the therapy of equine recurrent uveitis (ERU) in form of a suprachoroidal CsA-implant which achieves high drug concentrations in the vitreous. This should be particularly effective in the Appaloosa horse which shows a special...

Ocular ultrasonography in horses represents a valuable imaging diagnostic tool for the diagnosis of intraocular and periocular diseases, particularly when cornea or lens opacities preclude ophthalmoscopy of deeper structures. The authors studied normal and pathological aspects of the eye. Nineteen ...

The aim of this study was to describe the occurrence of individual clinical symptoms associated with equine recurrent uveitis (ERU) and compare the diagnostic yield of direct ophthalmoscopy and ultrasonography (B-mode imaging). The collection of evaluated horses included patients treated in the...

The effects of an intravitreal device releasing cyclosporine A (CsA) on recurrent inflammatory episodes in experimental uveitis in horses is studied. Nine normal horses were immunized peripherally with H37RA-mTB antigen twice, then intravitreally given 25 µg of H37RA-mTB antigen in the right eye...

Vitrectomy was performed in 12 horses with chronic ERU. At follow-up examinations of 11 operated eyes, 9 had normal i.o. pressure. The vitreous chambers were clear in 9 cases, 2 contained only small floaters. Two eyes with preoperative posterior synechia had subnormal i.o. pressure. No recurrences...