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Abstract

Aims: To compare urine urinary pH, blood pH and concentration of electrolytes in blood of healthy horses fed an anionic salt supplement to achieve diets with a dietary cation-anion difference (DCAD) of -40 or 0 mEq/kg DM, with horses a fed a diet with a DCAD of 85 mEq/kg DM. Methods: Eight healthy ...

Author(s)
Nelson, E. A.; Sanchez, L. C.; Mallicote, M. F.; Warren, L. K.; Robelen, A. M.; Reuss, S. M.
Publisher
Taylor & Francis, Melbourne, Australia
Citation
New Zealand Veterinary Journal, 2020, 68, 1, pp 60-64
Abstract

Background: Clodronate is a non-nitrogenated bisphosphonate approved for use in horses. There are no peer-reviewed published reports describing the pharmacokinetics or evaluating renal health indices and urinary excretion patterns in conjunction with plasma and synovial fluid concentration...

Author(s)
Krueger, C. R.; Mitchell, C. F.; Leise, B. S.; Knych, H. K.
Publisher
Wiley, Oxford, UK
Citation
Equine Veterinary Journal, 2020, 52, 5, pp 725-732
Abstract

Objective: To quantify the time to clear dexamethasone from plasma and urine of horses following a single nebulisation. Design: Experimental using six Standardbred mares. Methods: Dexamethasone sodium phosphate (0.04 mg/kg) diluted in 0.9% sodium chloride was administered as an aerosol using a...

Author(s)
Symonds, N. E.; Dart, A. J.; Keledjian, J.; Lau, M. L.; Ennis, L. C.; McIver, V. C.; Tsang, A. S.; Biasutti, S. A.; Jeffcott, L. B.
Publisher
Wiley, Melbourne, Australia
Citation
Australian Veterinary Journal, 2019, 97, 5, pp 144-148
Abstract

Objective: To monitor cobalt concentrations in urine, red blood cells and plasma after chronic parenteral administration of cobalt chloride evaluate these results against the current International Federation of Horseracing Authorities thresholds for detecting cobalt misuse. Design: Eight mares were ...

Author(s)
Wenzel, R. G.; Major, D.; Hesp, K. F.; Hall, E.; Doble, P.
Publisher
Wiley, Melbourne, Australia
Citation
Australian Veterinary Journal, 2019, 97, 11, pp 465-472
Abstract

Objective: Non-steroidal anti-inflammatory drugs are inhibitors of cyclooxygenase (COX) in tissues and used as therapeutic agents in different species. Grapiprant, a member of the piprant class of compounds, antagonizes prostaglandin receptors. It is a highly selective EP4 prostaglandin E2 receptor ...

Author(s)
Cox, S.; Sommardahl, C.; Fortner, C.; Davis, R.; Bergman, J.; Doherty, T.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2020, 47, 5, pp 705-706
Abstract

Detection of equine acute kidney injury (AKI) is hindered by limited markers of early renal damage in horses. N-acetyl-β-D-glucosaminidase (NAG), a lysosomal enzyme in renal tubular epithelium released into urine during tubular insult, has shown promise for early identification of AKI in humans and ...

Author(s)
Bayless, R. L.; Moore, A. R.; Hassel, D. M.; Byer, B. J.; Landolt, G. A.; Nout-Lomas, Y. S.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Journal of Veterinary Diagnostic Investigation, 2019, 31, 5, pp 688-695
Abstract

Background: Measurements of water consumed by fed healthy horses might not apply to horses that are unwilling or unable to drink or are not fed for any reason. Objective: To examine the effects of feed deprivation on voluntary water consumption compared with fed conditions. Study design: In vivo...

Author(s)
Freeman, D. E.; Mooney, A.; Giguère, S.; Claire, J.; Evetts, C.; Diskant, P.
Publisher
Wiley, Oxford, UK
Citation
Equine Veterinary Journal, 2021, 53, 1, pp 117-124
Abstract

Objective: To describe the pharmacokinetics and selected pharmacodynamic variables of codeine and its metabolites in Thoroughbred horses following a single oral administration. Study design: Prospective experimental study. Animals A total of 12 Thoroughbred horses, nine geldings and three mares,...

Author(s)
Gretler, S. R.; Finno, C. J.; McKemie, D. S.; Kass, P. H.; Knych, H. K.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2020, 47, 5, pp 694-704
Abstract

Background: Meperidine is a synthetic opioid that belongs to the phenylpiperidine class and is a weak mu receptor agonist. In horses there are a limited number of published studies describing the analgesic effects of systemically administered meperidine in horses. The objective of this study was to ...

Author(s)
Hamamoto-Hardman, B. D.; Steffey, E. P.; McKemie, D. S.; Kass, P. H.; Knych, H. K.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2020, 16, 368, pp (1 October 2020)
Abstract

For magnesium supplementation in horses, dosages for MgO, MgCO3, and MgSO4 were described previously. However, for magnesium as magnesium aspartate-hydrochloride (MAH) dose-dependent effects on the magnesium levels have not yet been determined in horses. Therefore, the magnesium concentrations in ...

Author(s)
Stöckle, S. D.; Müller, E.; Winter, J. C.; Sponder, G.; Aschenbach, J. R.; Pieper, L.; Gehlen, H.
Publisher
Hippiatrika Verlag GmbH, Baden-Baden, Germany
Citation
Pferdeheilkunde, 2019, 35, 6, pp 529-534, 536

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