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Abstract

We hypothesised that horses affected with summer pasture-associated obstructive pulmonary disease (SPAOPD) react to an allergen or allergens in their summer environment that is either absent or present at lower levels in their winter environment; and that such allergens stimulate SPAOPD-affected ...

Author(s)
Beadle, R. E.; Horohov, D. W.; Gaunt, S. D.
Publisher
Equine Veterinary Journal Ltd, Newmarket, UK
Citation
Equine Veterinary Journal, 2002, 34, 4, pp 389-394
Abstract

Objective - To immunohistochemically determine the expression of endothelin (ET) receptors in bronchial smooth muscle and epithelium of healthy horses and horses affected by summer pasture-associated obstructive pulmonary disease (SPAOPD). Sample Population - Tissue specimens obtained from 8...

Author(s)
Polikepahad, S.; Paulsen, D. B.; Moore, R. M.; Costa, L. R. R.; Venugopal, C. S.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2006, 67, 2, pp 348-357
Abstract

Objective - To identify differentially expressed genes in pulmonary tissues of horses affected with summer pasture-associated obstructive pulmonary disease (SPAOPD), which is a form of recurrent airway obstruction (RAO), compared with those of unaffected horses. Animals - 6 horses with SPAOPD-RAO...

Author(s)
Venugopal, C. S.; Mendes, L. C. N.; Peiró, J. R.; Laborde, S. S.; Stokes, A. M.; Moore, R. M.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2010, 71, 4, pp 476-482
Abstract

Clinical score, change in intra-pleural pressure (ΔPpl) during tidal breathing, results of cytological examination and bacteriological culture of bronchoalveolar lavage fluid (BALF), and results of histological examination of pulmonary parenchyma were evaluated 8 adult horses with summer pasture-...

Author(s)
Costa, L. R. R.; Seahorn, T. L.; Moore, R. M.; Taylor, H. W.; Gaunt, S. D.; Beadle, R. E.
Citation
American Journal of Veterinary Research, 2000, 61, 2, pp 167-173
Abstract

Eight horses, 14 to 23 years old, with previous diagnosis of summer pasture-associated obstructive pulmonary disease (SPAOPD) and 8 horses, 6 to 9 years old, with no evidence of respiratory tract disease, were examined twice during a 1-year period: when all SPAOPD-affected horses were manifesting...

Author(s)
Seahorn, T. L.; Beadle, R. E.; McGorum, B. C.; Marley, C. L.
Citation
American Journal of Veterinary Research, 1997, 58, 12, pp 1408-1411
Abstract

The purpose of this study was to evaluate the role of endothelin-1 (ET-1) and its receptors in the airway hyperreactivity of horses with obstructive pulmonary disease associated with summer pasture (SPAOPD). The right diaphragmatic lobe of the lung of 8 clinically healthy (unaffected) and 8 ...

Author(s)
Venugopal, C. S.; Polikepahad, S.; Holmes, E. P.; Heuvel, J. vanden; Leas, T. L.; Moore, R. M.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Journal of Veterinary Research, 2006, 70, 1, pp 50-57
Abstract

A study was conducted to compare responses of bronchial ring obtained from healthy horses (n=6) and horses affected with summer pasture-associated obstructive pulmonary disease (SPAOPD; n=6) to selected mediators of airway hyperreactivity in vitro. Bronchial rings obtained from each group of horses ...

Author(s)
Venugopal, C. S.; Moore, R. M.; Holmes, E. P.; Koch, C. E.; Seahorn, T. L.; Beadle, R. E.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2001, 62, 2, pp 259-263
Abstract

The response of parenchymal strips from guineapig lungs to tracheobronchial lavage fluid (TBLF) collected from 8 normal horses and from 8 affected with summer pasture-associated obstructive pulmonary disease (SPAOPD) was investigated. TBLF was collected during the summer (July) and winter...

Author(s)
Venugopalan, C. S.; Beadle, R. E.; Seahorn, T. L.; Holmes, E. P.
Citation
Veterinary Research Communications, 1998, 22, 7, pp 493-503
Abstract

The severity of summer pasture-associated obstructive pulmonary disease (SPAOPD) in seven adult horses was determined by use of clinical scores, change in intrapleural pressure (ΔPpl) during tidal breathing, cytologic analysis of BALF, and histologic evaluation of lung specimens obtained during...

Author(s)
Costa, L. R. R.; Seahorn, T. L.; Moore, R. M.; Oliver, J. L.; Hosgood, G. L.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2001, 62, 9, pp 1381-1386
Abstract

Severe equine asthma (EA) is the newly adopted term which defines the syndromes most recently known as recurrent airway obstruction (RAO; syn chronic obstructive pulmonary disease, Heaves) or summer pasture associated recurrent airway obstruction (SPARAO; syn summer pasture associated obstructive ...

Author(s)
Pirie, R. S.
Publisher
MA Healthcare Limited, London, UK
Citation
Livestock, 2017, 22, 4, pp 208-215

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