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Abstract

OBJECTIVE: To determine whether administration of trimethoprim-sulfadiazine (TMS), detomidine (DET), or TMS plus DET would be associated with changes in ECG repolarization parameters in horses. ANIMALS: 9 healthy adult horses. PROCEDURES: Each horse received 4 treatments in a blinded, randomized,...

Author(s)
Trachsel, D. S.; Calloe, K.; Jørgensen, E.; Lunddahl, C. S.; Pedersen, P. J.; Kanters, J. K.; Klaerke, D. A.; Buhl, R.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2021, 82, 3, pp 207-217
Abstract

Background: There are currently no evidence summaries on wounds in the horse. Objectives: To develop evidence-based guidelines on wound management in the horse. Study design: Evidence review using the GRADE framework. Methods: Research questions were proposed by a panel of veterinarians, and...

Author(s)
Freeman, S. L.; Ashton, N. M.; Elce, Y. A.; Hammond, A.; Hollis, A. R.; Quinn, G.
Publisher
Wiley, Oxford, UK
Citation
Equine Veterinary Journal, 2021, 53, 1, pp 18-29
Abstract

The objective of this experiment was to assess the concentrations of sulfadiazine and trimethoprim in the blood and endometrium of nonpregnant mares after oral treatment. We hypothesized that the potentiated sulfonamide would reach tissue concentrations greater than the minimum inhibitory...

Author(s)
Davolli, G. M.; Beavers, K. N.; Medina, V.; Sones, J. L.; Pinto, C. R. F.; Paccamonti, D. L.; Causey, R. C.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2018, 67, pp 27-30
Abstract

The long QT syndrome (LQTS) is a channelopathy that can lead to severe arrhythmia and sudden cardiac death. Pharmacologically induced LQTS is caused by interaction between drugs and potassium channels, especially the Kv11.1 channel. Due to such interactions, numerous drugs have been withdrawn from...

Author(s)
Trachsel, D. S.; Tejada, M. A.; Christensen, V. G.; Pedersen, P. J.; Kanters, J. K.; Buhl, R.; Calloe, K.; Klaerke, D. A.
Publisher
Wiley, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2018, 41, 4, pp 536-545
Abstract

OBJECTIVE: To determine the effects of 3 topically applied treatments (1% silver sulfadiazine cream [SSC], triple antimicrobial ointment [TAO], and hyperosmolar nanoemulsion [HNE]) on microbial counts, exuberant granulation tissue (EGT) development, and reepithelialization of contaminated wounds at ...

Author(s)
Harmon, C. C. G.; Hawkins, J. F.; Li JianMing; Connell, S.; Miller, M.; Saenger, M.; Freeman, L. J.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2017, 78, 5, pp 638-646
Abstract

Objective - To evaluate the effectiveness of a novel trimethoprim-sulfadiazine oral suspension for the treatment of naturally acquired Streptococcus equi subsp. zooepidemicus infection in horses. Design - Randomized, controlled field trial. Animals-180 horses with S. equi subsp. zooepidemicus...

Author(s)
McClure, S. R.; Koenig, R.; Hawkins, P. A.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
Journal of the American Veterinary Medical Association, 2015, 246, 12, pp 1345-1352
AbstractFull Text

BACKGROUND: Equine wounds, particularly those involving the distal portion of the limbs, often undergo prolonged complex healing and may enter a non-healing state with obvious financial and welfare implications. Poor blood supply and lower levels of oxygen to the lower limbs lead to imbalance of...

Author(s)
Khashjoori, B. K.; Ghamsari, S. M.; Dehghan, M. M.; Mohajeri, S. F.; Gholami, H.; Golshahi, H.
Publisher
Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Citation
Iranian Journal of Veterinary Medicine, 2019, 13, 1, pp 11-25
Abstract

A 4-year-old trotter gelding was treated homeopathically for delayed wound healing after surgery associated with antimicrobial-resistant bacteria. The horse failed to respond to antibiotic treatment with intravenous gentamicin and penicillin followed by oral sulfadiazine natrium and trimethoprim....

Author(s)
Weiermayer, P.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2018, 67, pp 37-43
Abstract

Antimicrobial susceptibility test results for trimethoprim-sulfadiazine with Streptococcus equi subspecies are interpreted based on human data for trimethoprim-sulfamethoxazole. The veterinary-specific data generated in this study support a single breakpoint for testing...

Author(s)
Sadaka, C.; Kanellos, T.; Guardabassi, L.; Boucher, J.; Watts, J. L.
Publisher
American Society for Microbiology (ASM), Washington, USA
Citation
Journal of Clinical Microbiology, 2017, 55, 1, pp 326-330
Abstract

Autologous platelet-rich plasma (PRP) is beneficial in the healing process of reconstructive surgeries, contributing to the stimulation of angiogenesis; however, heterologous plasma has been shown to be more effective. The objective of this study was to verify, by macro- and microscopic evaluation, ...

Author(s)
Rezende, R. S. de; Eurides, D.; Alves, E. G. L.; Venturini, G. C.; Felipe, R. L. de
Publisher
Universidade Federal de Goiás, Escola de Veterinária, Goiânia, Brazil
Citation
Ciência Animal Brasileira, 2020, 21,

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