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Abstract

Background: Standing surgery, especially dental procedures, are commonly performed in horses. This leads to an increasing demand for reliable sedation protocols. Therefore, it was the purpose of this study to investigate the influence of butorphanol, midazolam or ketamine on romifidine based...

Author(s)
Müller, T. M.; Hopster, K.; Bienert-Zeit, A.; Rohn, K.; Kästner, S. B. R.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2017, 13, 381, pp (6 December 2017)
Abstract

Objective: To evaluate the effect of a romifidine infusion on antinociception and sedation, and to investigate its relationship with plasma concentration. Study design: Prospective, experimental, nonrandomized trial. Animals: A total of 10 healthy adult warmblood horses. Methods: Romifidine...

Author(s)
Bernal, S. D.; Studer, N.; Thormann, W.; Spadavecchia, C.; Levionnois, O.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2020, 47, 1, pp 129-136
Abstract

During painful procedures at the head effective analgesia is necessary in horses. Therefore it was the aim of our study to evaluate the thermal antinociceptive effects of romifidine, ketamine, lidocaine and of the combination of romifidine with ketamine or lidocaine. The study was carried out in 6...

Author(s)
Wittenberg-Voges, L.; Iburg, K.; Hopster, K.; Rohn, K.; Kästner, S. B. R.
Publisher
Hippiatrika Verlag GmbH, Baden-Baden, Germany
Citation
Pferdeheilkunde, 2016, 32, 5, pp 428...435
Abstract

Objective: To evaluate the antinociceptive effect of a bolus of intravenous levomethadone administered to horses during romifidine constant rate infusion (CRI). Study design: Prospective, randomized, masked, crossover experimental study. Animals: A group of eight adult Warmblood horses (seven...

Author(s)
Studer, N.; Bernal, S. D.; Thormann Wolfgang; Levionnois, O.; Spadavecchia, C.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2021, 48, 3, pp 451-460
Abstract

The study was performed to evaluate the influence of the addition of either ketamine or midazolam to a romifidine-butorphanol bolus followed by a constant rate infusion (CRI) on the quality of sedation during tooth extraction in horses. Forty-five client-owned horses presented for dental...

Author(s)
Hopster, K.; Bienert-Zeit, A.; Hopster-Iversen, C.; Kästner, S. B. R.
Publisher
Hippiatrika Verlag GmbH, Stuttgart, Germany
Citation
Pferdeheilkunde, 2013, 29, 2, pp 220...227
Abstract

To examine the influence of detomidine or romifidine on recovery quality from isoflurane anesthesia, 78 anesthetic records were reviewed, from horses that had received romifidine (group R) during premedication [80-120 μg kg-1 IV], anesthetic maintenance (40 μg kg-1 hour-1 IV), and recovery (20 μg...

Author(s)
Alonso, B. B.; Rosa, L. la; Carregaro, A. B.; Gasthuys, F.; Schauvliege, S.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2020, 94,
Abstract

The aims of this study were to assess the plasma concentrations of romifidine in horses after intravenous injection, to evaluate the red blood cell (RBC) partitioning of the anaesthetic drug, and to improve knowledge regarding its sedative effect in horses describing the pharmacokinetic model....

Author(s)
Romagnoli, N.; Al-Qudah, K. M.; Armorini, S.; Lambertini, C.; Zaghini, A.; Spadari, A.; Roncada, P.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Medicine and Science, 2017, 3, 4, pp 187-197
Abstract

Post-anaesthetic colic (PAC) has been reported as one of the most common peri-anaesthetic complication in horses. There is limited amount of information on the effects of anaesthetic regimes and the incidence of PAC. We analysed the medical records of horses anaesthetised at University of Helsinki...

Author(s)
Pekkola, V.; Tapio, H.; Junnila, J.; Menzies, M. P. L.
Publisher
Suomen Eläinlääkäriliitto, Helsinki, Finland
Citation
Suomen Eläinlääkärilehti, 2019, 125, 9, pp 565-572
Abstract

Objectives: To investigate the effects of MK-467 on sedation quality, and cardiopulmonary and pharmacokinetic variables in horses sedated intravenously (IV) with romifidine. Study design: Experimental, randomized, crossover design. Animals: Seven healthy mares. Methods: Romifidine (80 µg kg-1; R)...

Author(s)
Vries, A. de; Pakkanen, S. A. E.; Raekallio, M. R.; Ekiri, A.; Scheinin, M.; Taylor, P. M.; Vainio, O. M.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2016, 43, 6, pp 599-610
Abstract

Romifidine is an alpha-2 adrenergic agonist used for sedation and analgesia in horses. As it is a prohibited substance, its purported use at low doses in performance horses necessitates further study. The primary goal of the study reported here was to describe the serum concentrations and...

Author(s)
Knych, H. K.; Stanley, S. D.; McKemie, D. S.; Steinmetz, S. J.
Publisher
Wiley, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2017, 40, 5, pp 569-574

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