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In the horse, the term occipitoatlantoaxial malformation (OAAM) is used to describe a developmental defect in which the first cervical vertebra (atlas) resembles the base of the skull (occiput) and the second cervical vertebra (axis) resembles the atlas. Affected individuals demonstrate an abnormal ...
A 3-year-old Warmblood mare was presented with spinal ataxia of 3 months' duration. Clinically, reduced mobility of the neck and a prominent atlas were identified. Neurological evaluation revealed hypermetria, circumduction and reduced proprioception, predominantly in the hindlimbs. ...
Background: The carrier status of lavender foal syndrome (LFS), cerebellar abiotrophy (CA), severe combined immunodeficiency (SCID), and occipitoatlantoaxial malformation (OAAM1) in foals with juvenile idiopathic epilepsy (JIE) is unknown. Hypothesis/Objectives: To determine the carrier status of...
Genetic diseases of horses differ according to the way of inheritance (dominant or recessive) and may cause functional disorders of different systems. Defects in genes can cause disorders of muscle or skeletal system (Hipercalemic Periodic Paralysis, HYPP; Occipitoatlantoaxial Malformation, OAAM),...
A case of an occipitoatlantoaxial malformation in an adult Spanish purebred mare is described. The animal suddenly developed incoordination, hind quarters paralysis and ultimately postration. Following euthanasia, necropsy revealed asymmetric fusion of the atlanto-occipital joint, involving the...