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Abstract

Objective: To determine if corneal epithelial cell integrity is detrimentally affected by short-term administration of 1.0% morphine sulfate. Additionally, we sought to determine if topical 1.0% morphine applied to the equine cornea would result in ocular or systemic absorption. Animal: studied Six ...

Author(s)
Gordon, E.; Stang, B. V.; Heidel, J.; Poulsen, K. P.; Cebra, C. K.; Schlipf, J. W., Jr.
Publisher
Wiley, Boston, USA
Citation
Veterinary Ophthalmology, 2018, 21, 5, pp 516-523
Abstract

Standing surgery under sedation reduces anesthetic-related mortality in horses. Medetomidine, alone and combined with morphine in a constant rate infusion (CRI), has been described for standing surgery but their cardiorespiratory, sedative and antinociceptive effects have never been compared. The...

Author(s)
Troya-Portillo, L.; López-Sanromán, J.; Villalba-Orero, M.; Santiago-Llorente, I.
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2021, 11, 7,
Abstract

Objective: Various drugs administered to horses undergoing surgical procedures can release histamine. Histamine concentrations were evaluated in horses prepared for surgery and administered butorphanol or morphine intraoperative infusions. Study design: Prospective studies with one randomized....

Author(s)
Duke-Novakovski, T.; Jimenez, C. P.; Fujiyama, M.; Beazley, S. G.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2021, 48, 1, pp 17-25
Abstract

Background In humans, the drug metabolizing enzyme CYP2D6 is highly polymorphic resulting in substantial differences in the metabolism of drugs including anti-arrhythmics, neuroleptics, and opioids. The objective of this study was to phenotype a population of 100 horses from five different breeds...

Author(s)
Gretler, S. R.; Finno, C. J.; Kass, P. H.; Knych, H. K.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2021, 17, 77, pp (13 February 2021)
Abstract

The objective of the present study was to compare, using accelerometry, the gait changes produced after administration of a dose of 0.2 mg/kg of morphine at the walk in healthy horses. Six mature horses were used, and all animals received two different treatments with, at least, two weeks interval...

Author(s)
López-Sanromán, F. J.; Freilich, G. M.; Gomez-Cisneros, D.; Varela, M.; Santiago, I.; Manso-Díaz, G.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2021, 104,
Abstract

The study aim is to compare the effects of epidural administration of two different doses of romifidine combined with morphine in horses. A prospective crossover blinded experimental design was used. Five adult healthy horses two males and three females with a mean body weight of 380 ± 45 Kg...

Author(s)
Natalini, C. C.; Paes, S. D. L. A.; Polydoro, A. da S.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2021, 102,
Abstract

Background: There are no data investigating the effect of systemic morphine on the size of the stomach or the food consumption in horses. Objectives: To evaluate gastrointestinal side effects of morphine administered systemically in healthy horses by the means of clinical and ultrasonographic...

Author(s)
Tessier, C.; Pitaud, J. P.; Thorin, C.; Touzot-Jourde, G.
Publisher
Wiley, Oxford, UK
Citation
Equine Veterinary Journal, 2019, 51, 5, pp 653-657
Abstract

Objective: To describe the pharmacokinetics and selected pharmacodynamic variables of codeine and its metabolites in Thoroughbred horses following a single oral administration. Study design: Prospective experimental study. Animals A total of 12 Thoroughbred horses, nine geldings and three mares,...

Author(s)
Gretler, S. R.; Finno, C. J.; McKemie, D. S.; Kass, P. H.; Knych, H. K.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2020, 47, 5, pp 694-704
Abstract

Objective: To evaluate perioperative stress-related hormones in isoflurane-anesthetized horses administered infusions of dexmedetomidine alone or with butorphanol or remifentanil, compared with ketamine-morphine. Study design: Randomized, prospective, nonblinded clinical study. Animals: A total of...

Author(s)
Fujiyama, M.; Jones, T.; Duke-Novakovski, T.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2021, 48, 3, pp 344-355
Abstract

Caudal epidural analgesia is a well-established therapeutic modality for pain alleviation in horses. Additionally, epidural analgesia could potentially be a complementary diagnostic tool for confirmation of pain-related conditions in horses presenting with nonspecific signs of poor performance or...

Author(s)
Kjærulff, L. N. R.; Lauritsen, N. J. D.; Ekstrøm, C. T.; Østergaard, S.; Olsen, E.; Laursen, S. H.; Lindegaard, C.
Publisher
Wiley, Oxford, UK
Citation
Equine Veterinary Education, 2021, 33, 7, pp 360-367

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