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Abstract

OBJECTIVE: To determine plasma pharmacokinetics of metronidazole and imipenem following administration of a single dose PO (metronidazole, 15 mg/kg) or IV (imipenem, 10 mg/kg) in healthy Thoroughbreds and simulate pleural fluid concentrations following multiple dose administration every 8 hours....

Author(s)
Kuroda, T.; Nagata, S. I.; Tamura, N.; Kinoshita, Y.; Niwa, H.; Mita, H.; Minami, T.; Fukuda, K.; Hobo, S.; Kuwano, A.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2020, 81, 10, pp 783-789
Abstract

Antibiotic administration can be a cause of gastrointestinal disease in horses, creating a disruption in the normal population and function of bacteria found in the hindgut. The objective of this study was to describe the changes in the cecal and fecal microbiomes and metabolomes of clinically...

Author(s)
Arnold, C. E.; Isaiah, A.; Pilla, R.; Lidbury, J.; Coverdale, J. S.; Callaway, T. R.; Lawhon, S. D.; Steiner, J.; Suchodolsk, J. S.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2020, 15, 5,
Abstract

In a randomized crossover design study, 10 adult horses were administered crushed metronidazole tablets rectally at 20 mg/kg. Horses' rectums were either evacuated (E) or not evacuated (NE) of manure prior to the administration of the drug. Serum samples were taken over 24 hr and plasma...

Author(s)
Stein, F.; Gilliam, L.; Davis, J.; Taylor, J.
Publisher
Wiley, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2018, 41, 6, pp 838-842
Abstract

Metronidazole-induced central vestibular syndrome (CVS) is uncommon in horses. A case of CVS following treatment with metronidazole at therapeutic doses is reported. An adult male mixed breed horse was submitted to antimicrobial therapy with metronidazole (15 mg.kg-1 IV), penicillin-streptomycin...

Author(s)
Nóbrega, F. S.; Ferreira, M. P.; Voll, J.; Sperb, M.; Garbade, P.
Publisher
Faculdade de Ciências Agrárias e Veterinárias, Câmpus de Jaboticabal, UNESP, Jaboticabal, Brazil
Citation
Ars Veterinaria, 2015, 31, 1, pp 24-27
AbstractFull Text

This paper aims to describe the clinical, microbiological, and pathological aspects of actinobacillosis in the oral cavity of a horse. Case: A case of actinobacillosis has been reported in a 22-year-old gelding Quarter Horse. According to the owner, the animal presented with progressive weight loss ...

Author(s)
Toma, H. S.; Carvalho, M. B.; Mattos Carvalho, A. de; Cruz, R. A. S. da; Schein, F. B.; Martins, K. P. F.; Toma, C. D. M.; Silva Cabral, L. da
Publisher
Universidade Federal do Rio Grande do Sul, Faculdade de Veterinária, Porto Alegre, Brazil
Citation
Acta Scientiae Veterinariae, 2020, 48, (Suppl 1): 478,
AbstractFull Text

Oral squamous cell carcinoma is responsible for more than 90% of head and neck neoplasms in humans. Multiple factors are associated with the development of squamous cell carcinomas in humans and animals, such as prolonged exposure to ultraviolet light, lack of pigment in the epidermis, or sparse...

Author(s)
Ferreira, M. L.; Alzamora Filho, F.; Mery, R. B. G.; Santos, J. S. de S.; Barros, J. R. de S.; Machado, M. C.; Silva, M. V. A. da; Silva, P. C.
Publisher
Universidade Federal do Rio Grande do Sul, Faculdade de Veterinária, Porto Alegre, Brazil
Citation
Acta Scientiae Veterinariae, 2020, 48, (Suppl 1): 503,
AbstractFull Text

This work aimed to report the clinical case of a female horse of the Paint horse race, approximately six years old, attended at the University Veterinary Hospital of the Federal University of Piauí, with clinical tetanus. Disease caused by toxins, tetanospasmin and tetanolysin, produced by...

Author(s)
Pereira, A. L. de A.; Gonçalves, T. F.; Dantas, J. B. G.; Oliveira, M. P. M. de; Gomes, J. B.; Tolentino, M. L. D. de L.; Pereira, E. A.; Martins e Silva, K. de F.; Sousa, D. C. de; Filho, M. L. da S.
Publisher
Pubvet, Maringá, Brazil
Citation
PUBVET, 2019, 13, 6,
Abstract

Metronidazole is a nitroimidazole antibacterial and antiprotozoal drug with bacteriocidal activity against a broad range of anaerobic bacteria. It is a recognized treatment for elephants diagnosed with anaerobic bacterial infection or protozoal disease or exhibiting signs of colonic impaction,...

Author(s)
Sander, S. J.; Siegal-Willott, J. L.; Ziegler, J.; Lee, E.; Tell, L.; Murray, S.
Publisher
American Association of Zoo Veterinarians, Pomona, USA
Citation
Journal of Zoo and Wildlife Medicine, 2016, 47, 1, pp 1-5
Abstract

Background: Complications following open standing castration (OSC) in Thoroughbred racehorses are well recognised but variation in their prevalence and severity between populations is not well documented. Objectives: To describe the prevalence and severity of complications in the 30 days following...

Author(s)
Rosanowski, S. M.; MacEoin, F.; Graham, R. J. T. Y.; Riggs, C. M.
Publisher
Wiley, Oxford, UK
Citation
Equine Veterinary Journal, 2018, 50, 3, pp 327-332
Abstract

Clostridium difficile has been recovered from the faeces of several animal species as well as horses. Between April 2015 and October 2016, 213 samples of faeces from non-hospitalized (n=138) and hospitalized horses (n=75) were investigated and eighteen C. difficile isolates were cultured using an...

Author(s)
Kecerova, Z.; Cizek, A.; Nyc, O.; Krutova, M.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Anaerobe, 2019, 56, pp 17-21

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