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Abstract

Objective: To determine time to first passage of feces, total fecal piles and incidence of colic in the first 24 hours postprocedure in horses undergoing standing sedation with detomidine, or general anesthesia with or without detomidine. Study design: Retrospective cohort study. Animals: A total...

Author(s)
Thibault, C. J.; Wilson, D. V.; Robertson, S. A.; Sharma, D.; Kinsley, M. A.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2019, 46, 4, pp 458-465
Abstract

The aim of this randomized, double-blind, placebo-controlled, parallel group clinical field study was to evaluate the effect of detomidine oromucosal gel in alleviating anxiety and fear in horses. Sixteen horses with a history of acute anxiety and fear associated with firework-related noise entered ...

Author(s)
Dai, F.; Rausk, J.; Aspegren, J.; Huhtinen, M.; Cannas, S.; Minero, M.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2020, 6, October,
Abstract

In equine and racing practice, detomidine and butorphanol are commonly used in combination for their sedative properties. The aim of the study was to produce detection times to better inform European veterinary surgeons, so that both drugs can be used appropriately under regulatory rules. Three...

Author(s)
Paine, S. W.; Bright, J.; Scarth, J. P.; Hincks, P. R.; Pearce, C. M.; Hannan, C.; MacHnik, M.; Hillyer, L.
Publisher
Wiley, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2020, 43, 2, pp 162-170
Abstract

Background: The ideal field anaesthetic protocol for castration will offer an adequate duration and depth of anaesthesia using a single injection without compromising safety or recovery quality. Objectives: The objective of this study was to compare intravenous (IV) xylazine and detomidine as...

Author(s)
Smith, M. C.; Bass, L.; Damone, J.; Mama, K.; Rao, S.
Publisher
Wiley, Oxford, UK
Citation
Equine Veterinary Journal, 2020, 52, 4, pp 516-521
Abstract

Objective: To compare the efficacy of a medetomidine constant rate infusion (CRI) with a detomidine CRI for standing sedation in horses undergoing high dose rate brachytherapy. Study design: Randomized, controlled, crossover, blinded clinical trial. Animals: A total of 50 horses with owner consent, ...

Author(s)
Hollis, A. R.; Pascal, M.; Dijk, J. van; Jolliffe, C.; Kaartinen, J.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2020, 47, 1, pp 76-81
Abstract

Alpha-2-adrenoceptor agonists are sedatives that can cause fluctuations in serum insulin and blood glucose (BG) concentrations in horses. The objectives of this study were to investigate the effects of detomidine and vatinoxan on BG, insulin, and glucagon concentrations in horses with and without...

Author(s)
Box, J. R.; Karikoski, N. P.; Tanskanen, H. E.; Raekallio, M. R.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Journal, 2021, 269,
Abstract

Objective: To compare the effects of two different doses of butorphanol combined with detomidine administered intravenously (IV) on quality of sedation, degree of ataxia and anaesthetic induction in horses. Study design: Randomized, blinded, clinical study. Animals: A total of 40 client-owned...

Author(s)
Grauw, J. de; Loon, T. van
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2020, 47, 5, pp 681-685
Abstract

Background: In metabolically stable horses, alpha-2-agonists suppress insulin secretion with transient hyperglycemia and rebound hyperinsulinemia. In horses with insulin dysregulation (ID), the effect of alpha-2-agonists has not been investigated; however, both the alpha-2-agonist-induced...

Author(s)
Kritchevsky, J. E.; Muir, G. S.; Leschke, D. H. Z.; Hodgson, J. K.; Hess, E. K.; Bertin, F. R.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2020, 34, 2, pp 902-908
Abstract

Objectives: To determine the sedative effects and pharmacokinetic profile of detomidine when administered intravaginally as a gel formulation to horses. Study design: Randomized, crossover, masked experimental design. Animals: A group of six healthy adult mares (494±56 kg). Methods: Mares were...

Author(s)
Seddighi, R.; Knych, H. K.; Cox, S. K.; Sun XiaoCun; Moorhead, K. A.; Doherty, T. J.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2019, 46, 6, pp 772-779
Abstract

Background: Chemical restraint is often used to perform diagnostic and minor surgical procedures; α2-adrenoceptor agonists are the most commonly used drugs; however, the combination with an opiate can induce a profound sedation. There is a lack of kinematic studies examining the effects of the...

Author(s)
Frigerio, M. A.; Cisneros, D. G.; Llorente, I. S.; Manso-Díaz, G.; López-Sanromán, J.
Publisher
Wiley, Oxford, UK
Citation
Equine Veterinary Journal, 2019, 51, 6, pp 825-830

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