Background: The association of microbiota with clinical outcomes and the taxa associated with colitis in horses remains generally unknown. Objectives: Describe the fecal microbiota of horses with colitis and investigate the association of the fecal microbiota with the development of laminitis and...

Background: Equine colitis is a diarrhoeal disease caused by inflammation of the large bowel and can potentially be life-threatening due to its rapid progression. Pathogenesis is multifactorial and pathophysiology is highly complicated, therefore, reliable diagnostic biomarkers are needed in the...

Background and aims: Fecal microbial transplantation (FMT) is empirically implemented in horses with colitis to facilitate resolution of diarrhea. The purpose of this study was to assess FMT as a clinical treatment and modulator of fecal microbiota in hospitalized horses with colitis. Methods: A...

Background: Rates of detecting ≥1 potential enteric pathogens (PEP) or toxins (PEP-T) in feces, blood, or both of horses ≥6 months of age with enteric disease and impact of multiple detections on outcome of horses with colitis has not been reported. Objective: To determine detection rates of...

Non-steroidal anti-inflammatory drugs (NSAIDs) can cause right dorsal colitis, but longitudinal clinical studies are lacking. This study investigates whether NSAID treated horses develop right dorsal colonic pathology in a clinical setting. Non-gastrointestinal hospitalized horses treated with...

Background: The fecal microbiome of healthy horses may be influenced by signalment, diet, environmental factors, and disease. Objectives: To assess the effects of age, breed, sex, geographic location, season, diet, and colitis caused by antibiotic use (antimicrobial-associated diarrhea [AAD]) and ...

Objectives: To determine the impact of age on survival in horses with colitis and to elucidate whether a lower type-1/type-2 cytokine ratio or an exaggerated inflammatory state contribute to reduced survival in aged horses. Design: Part 1: Retrospective cohort analysis. Part 2: Analytic...

A 16-year-old Quarter Horse was examined and observed to have acute signs of colic, pyrexia, and diarrhea. A nephrosplenic entrapment was detected via rectal palpation and confirmed with abdominal ultrasound. The nephrosplenic entrapment was resolved non-surgically with jogging and...

Colitis X in the horse is defined as typhlocolitis with acute catarrhal haemorrhagic sometimes necrotized character which progresses rapidly and can lead to shock and death. The underlying cause has not yet been understood completely. A multifactorial process is supposed. In the study presented,...

Colitis X in horses is an acute catarrhal haemorrhagic sometimes necrotizing typhlocolitis which develops rapidly and can lead to shock and death. The underlying cause is still not known in detail, but a multifactorial process is supposed. The present study compares and discusses the facts of ...