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Abstract

Chloramphenicol is commonly used in horses; however, there are no studies evaluating the pharmacokinetics of veterinary canine-approved tablets. Studies using different formulations and earlier analytical techniques led to concerns over low bioavailability in horses. Safety concerns about human...

Author(s)
Trishna Patel; Magdesian, K. G.; Estell, K. E.; Edman, J. M.; Knych, H. K.
Publisher
Wiley, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2019, 42, 6, pp 609-616
Abstract

OBJECTIVE: To determine the pharmacokinetics of chloramphenicol base after PO administration at a dose of SO mg/kg (22.7 mg/lb) in adult horses from which food was not withheld. DESIGN: Prospective crossover study. ANIMALS: 5 adult mares. PROCEDURES: Chloramphenicol base (SO mg/kg) was administered ...

Author(s)
McElligott, E. M.; Sommardahl, C. S.; Cox, S. K.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
Journal of the American Veterinary Medical Association, 2017, 251, 1, pp 90-94
Abstract

We aimed to investigate the prevalence, molecular characteristics and risk factors of extended-spectrum -lactamase (ESBL)-producing Enterobacteriaceae (ESBL-E) shedding in horses. A prospective study included three cohorts: (i) farm horses (13 farms, n = 192); (ii) on hospital admission (n = 168)...

Author(s)
Shnaiderman-Torban, A.; Navon-Venezia, S.; Dor, Z.; Paitan, Y.; Arielly, H.; Wiessam Abu Ahmad; Kelmer, G.; Fulde, M.; Steinman, A.
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2020, 10, 2,
Abstract

Regional limb perfusion (RLP) significantly decreases morbidity and mortality associated with distal limb injuries in horses. There is an urgent need for finding additional effective antimicrobial drugs for use in RLP. In this study, we tested the pharmacokinetics (PK) of chloramphenicol in RLP....

Author(s)
Kelmer, G.; Tatz, A. J.; Famini, S.; Bdolah-Abram, T.; Soback, S.; Britzi, M.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2015, 38, 1, pp 35-40
Abstract

Horses are usually at risk of physical injuries/wounds because of their typical flight and fright temperament. These wounds are readily infected because of the nature of work they do. This study was a 6-month survey of wound infections of horses at the Obollo-Afor Horse Lairage, Udenu Local...

Author(s)
Agina, O. A.; Ihedioha, J. I.; Anyanwu, M. U.; Ngwu, M. I.
Publisher
Springer Science + Business Media, London, UK
Citation
Comparative Clinical Pathology, 2017, 26, 1, pp 181-188
AbstractFull Text

This study was conducted to isolate generic extended-spectrum cephalosporin (ESC)-resistant and extended-spectrum β-lactamase (ESBL)-producing enterobacteria from horses in Nigeria, and to determine the antibacterial resistance profile. Rectal swabs were collected from 155, systematic randomly...

Author(s)
Anyanwu, M. U.; Ugwu, I. C.; Onah, C. U.
Publisher
Sciendo, Warsaw, Poland
Citation
Macedonian Veterinary Review, 2018, 41, 2, pp 123-132
Abstract

This study was conducted to isolate generic enterococci from horses in Nigeria, and to determine the antibiotic resistance profile and phenotypic vancomycin (VAN) resistance of the isolates. Non-duplicate rectal swabs were collected from 200, randomly-selected apparently-healthy horses. Isolation...

Author(s)
Anyanwu, M. U.; Okorie-Kanu, O. J.; Ogugua, A. J.; Ezenduka, E. V.; Anidebe, C. O.
Publisher
École Nationale Vétérinaire de Toulouse, Toulouse, France
Citation
Revue de Médecine Vétérinaire, 2019, 170, 1/3, pp 46-52
Abstract

Background: Lawsonia intracellularis is the aetiologic agent of equine proliferative enteropathy (EPE). This emerging equine disease leads to diarrhoea, severe protein loss and can result in death if left untreated. Timely treatment of EPE is critical for recovery from the disease, and hence,...

Author(s)
Pereira, C. E. R.; Resende, T. P.; Vasquez, E.; Marshall-Lund, L.; Guedes, R. M. C.; Gebhart, C. J.
Publisher
Wiley, Oxford, UK
Citation
Equine Veterinary Journal, 2019, 51, 5, pp 665-668
AbstractFull Text

The aim of this study was to identify the conjunctival bacterial flora of healthy horses in Brasilia (Distrito Federal, Brazil), and to evaluate the antimicrobial susceptibility of the isolated strains. We examined 200 eyes of 100 healthy adult horses without any eye problems, belonging to the 1st...

Author(s)
Ferreira, A. R. de A.; Santana, A. F.; Almeida, A. C. da V. R. de; Sousa, R. F.; Perecmanis, S.; Galera, P. D.
Publisher
Centro de Ciências Rurais, Universidade Federal de Santa Maria, Santa Maria, Brazil
Citation
Ciência Rural, 2017, 47, 6, pp e20160753
Abstract

A method for the detection and confirmation of organic solvent extractable residues of the neutral, acidic, and basic analytes of the amphenicol class veterinary drugs and selected metabolites was developed and validated. Using a modified QuEChERS extraction with SPE cleanup and LC-MS/MS analysis,...

Author(s)
Fedeniuk, R. W.; Mizuno, M.; Neiser, C.; O'Byrne, C.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Journal of Chromatography, B, 2015, 991, pp 68-78

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