Bromhexine (BH), expectorant used in the treatment of respiratory disorders associated with viscid or excessive mucus, is not permitted for use in the competing horse by many authorities in horseracing and Olympic disciplines. Metabolic studies are of the great importance in anti-doping field...

Objectives - To evaluate the mucolytic activity of N-acetylcysteine (NAC) at different concentrations (2.5%, 5%, 10%, 20%) by measuring, in vitro, variations in viscosity and elasticity of mucus samples using a dynamic viscosimeter. Methods - Mucus samples were collected from 60 adult saddle horses ...

In 2016, only one newly developed active pharmaceutical ingredient for horses and food-producing animals was released on the German market for veterinary drug products. The immunomodulator Pegbovigrastim is now available as an injection solution for cattle (Imrestor®). Four established veterinary...

Mares (450-550 kg) were given 1 g of bromhexine or ambroxol in a feed of oats mixed with molasses. In a separate trial mares were given furosemide (300 mg i.v.) at 3 h before, at the same time or 1 h after dosing with bromhexine. Urine samples were collected before and up to 48 h after dosing with...

Bisolvon was administered for 11 days in powder form, mixed in the food, to five horses with different pulmonary conditions and one healthy horse, both at the recommended dosage (100 mg or 0.2 mg/kg daily) and at five times the recommended dosage. Samples of aspirated mucus were examined for...

The effect of this mucolytic agent in respiratory infections was studied in 55 horses and 9 cows. The results were compared with those of other methods of treatment and with reports in the literature. The drug had a positive effect in the cure of these infections. It can be especially recommended...

The experiences of a practising veterinary surgeon are described, with particular reference to chronic conditions. Three tables give the results of treatment of 43 horses with dexamethasone, bromhexine, a dexamethasone depot preparation, and supportive drugs. The dexamethasone depot preparation is...

The work in this paper has already been published in New Zealand Veterinary Journal (1978) 26 (1/2) pp. 28-30 [see VB 48, abst. 6145]. In this German version there has been some rearrangement of the text and in addition there is discussion of three individual cases which did not appear in the...

Fifteen horses with clinical respiratory disease were evaluated haematologically and radiographically. They were then treated with 15-20 g daily of bromhexine given in the feed, usually for 10 days, but for some up to 45 days. All showed marked improvement both clinically and radiographically....

From 1971 to 1981, 61 horses were brought to the College clinic with chronic obstructive pulmonary disease (COPD). More than half were over six years old, though laryngotracheitis and bronchiolitis were fairly frequent in young horses. The majority (57) were agricultural or domestic draught horses, ...