The aim of this study was to compare the effects of methadone combined with detomidine or acepromazine on the quality of sedation and its influence over dissociative anesthesia in healthy horses. In a crossover design, seven horses were administered with 0.1 mg/kg methadone and 0.02 mg/kg...

Purpose of the study: To determine the incidence of fatalities in horses undergoing general anesthesia for examinations or surgical procedures from 2006 to 2011 at an Equine University Clinic (Munich), to differentiate between fatalities occurring in the time period from induction of anesthesia to...

Background: The ideal field anaesthetic protocol for castration will offer an adequate duration and depth of anaesthesia using a single injection without compromising safety or recovery quality. Objectives: The objective of this study was to compare intravenous (IV) xylazine and detomidine as...

This study evaluated use of midazolam, ketamine, and xylazine (MKX) for total intravenous (IV) anesthesia (TIVA) in horses. Medical records of 46 horses undergoing a clinical procedure using MKX for TIVA were reviewed. Age, breed, procedure, heart rate (HR), respiratory rate (RR), pre-anesthetic...

Background: The bispectral index (BIS) has been evaluated as an indicator of central nervous system (CNS) depression in horses during general anaesthesia. The spectral entropy is another electroencephalographic device and it has not been evaluated yet in horses. Objectives: To determine if spectral ...

This study evaluated induction of anesthesia and cardiorespiratory and anesthetic effects during maintained anesthesia with the combination of alfaxalone, medetomidine, and butorphanol. Alfaxalone (1.0 mg/kg) was administered to induce anesthesia after premedication with medetomidine (7.0 µg/kg),...

Equine anesthesia has a high mortality rate compared to other animal species and human beings, partly due to the widespread use of inhalation agents as the only anesthetic agent, developing major cardiovascular and respiratory depression. Total intravenous anesthesia (TIVA), with the use of...

Background: The aim of the present study was to evaluate clinical efficacy of constant rate infusions (CRIs) of medetomidine-propofol combined with sevoflurane anesthesia in Thoroughbred racehorses undergoing arthroscopic surgery. Thirty horses were sedated intravenously (IV) with medetomidine (6.0 ...

Background: Alfaxalone has a number of pharmacological properties which are desirable for constant rate infusion (CRI). Previously, the co-administration of alfaxalone and medetomidine is shown to be suitable for short-term anesthesia in horses. However, the use of alfaxalone-medetomidine CRI with...

To examine the influence of detomidine or romifidine on recovery quality from isoflurane anesthesia, 78 anesthetic records were reviewed, from horses that had received romifidine (group R) during premedication [80-120 μg kg^-1 IV], anesthetic maintenance (40 μg kg^-1 hour^-1 IV), and recovery (20 μg...