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Abstract

A 12-year-old Thoroughbred cross Dartmoor mare was referred to the clinic with marked lameness and swelling involving the left stifle region. There was poor initial response to medical management and arthroscopic examination of the stifle joint was performed under general anaesthesia. Following...

Author(s)
Bruniges, N.; Milner, P.; Bardell, D.
Publisher
Wiley, Oxford, UK
Citation
Equine Veterinary Education, 2019, 31, 7, pp 354-362
Abstract

Background: Meperidine is a synthetic opioid that belongs to the phenylpiperidine class and is a weak mu receptor agonist. In horses there are a limited number of published studies describing the analgesic effects of systemically administered meperidine in horses. The objective of this study was to ...

Author(s)
Hamamoto-Hardman, B. D.; Steffey, E. P.; McKemie, D. S.; Kass, P. H.; Knych, H. K.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2020, 16, 368, pp (1 October 2020)
AbstractFull Text

Crotalphine is a novel analgesic peptide that acts on kappa opioid and delta receptors, causing powerful analgesia in rats submitted to inflammatory, neuropathic or oncologic models of pain. This study evaluated clinical, behavioral and antinociceptive effects caused by crotalphine in horses,...

Author(s)
Guirro, E. C. B. do P.; Perotta, J. H.; Paula, M. de; Cury, Y.; Valadão, C. A. A.
Publisher
Centro de Ciências Rurais, Universidade Federal de Santa Maria, Santa Maria, Brazil
Citation
Ciência Rural, 2016, 46, 4, pp 694-699
Abstract

Objective: Various drugs administered to horses undergoing surgical procedures can release histamine. Histamine concentrations were evaluated in horses prepared for surgery and administered butorphanol or morphine intraoperative infusions. Study design: Prospective studies with one randomized....

Author(s)
Duke-Novakovski, T.; Jimenez, C. P.; Fujiyama, M.; Beazley, S. G.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2021, 48, 1, pp 17-25
Abstract

Objective: To determine the influence of epidural detomidine and morphine on serum corticosteroid concentrations and pain-related behavioral responses in mares during and after ovariectomy via colpotomy. Study design: Blinded prospective study. Animals: Nine university-owned mares. Methods: Five of ...

Author(s)
Rowland, A. L.; Glass, K. G.; Grady, S. T.; Cummings, K. J.; Hinrichs, K.; Watts, A. E.
Publisher
Wiley, Boston, USA
Citation
Veterinary Surgery, 2018, 47, 5, pp 715-721
Abstract

Opioid analgesics have been the foundation of human pain management for centuries, and their value in animals has increased since it was proposed that it is the veterinarian's duty to alleviate pain whenever it may occur. Compared with other domesticated species, the horse has benefitted less from...

Author(s)
Clutton, R. E.
Publisher
Elsevier Inc.,, New York, USA
Citation
Veterinary Clinics of North America, Equine Practice, 2010, 26, 3, pp 493-514
Abstract

Opioid absorption in the intestinal tract as well as its effect in the central nervous system is regulated by the P-glycoprotein (P-gp) encoded in the Multi-drug resistance gene (MDR1). This gene acts as a selective pump. The expression of this protein in humans and rodents inhibits cellular uptake ...

Author(s)
Natalini, C. C.; Cunha, A. F. da; Linardi, R. L.
Publisher
Centro de Ciências Rurais, Universidade Federal de Santa Maria, Santa Maria, Brazil
Citation
Ciência Rural, 2006, 36, 1, pp 330-335
Abstract

Nalbuphine is a lipophilic semisynthetic κ-agonist/µ-antagonist opioid that has been used for epidural anesthesia in humans and dogs but not in donkeys. The purpose of the present study was to report the effect of epidural nalbuphine either alone or in combination with lidocaine compared with...

Author(s)
Torad, F. A.; Hassan, E. A.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2016, 37, pp 1-5
Abstract

Objective: To test the hypothesis that the distribution, density, and subtype of opioid and alpha (α)-2 adrenergic receptors within the central nervous system (CNS) are significantly different between horse and dog. Study design: Prospective experimental study. Animals: Three dogs (3 years of age)...

Author(s)
Hellyer, P. W.; Bai, L.; Supon, J.; Quail, C.; Wagner, A. E.; Mama, K. R.; Magnusson, K. R.
Publisher
Blackwell Science, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2003, 30, 3, pp 172-182
Abstract

In human and animal anesthesia, epidural and spinal administration of drugs is used to provide surgical anesthesia and/or postoperative analgesia. Several local anesthetic drugs are used to produce epidural anesthesia, such as lidocaine, bupivacaine, ropivacaine, and mepivacaine. Epidural analgesia ...

Author(s)
Natalini, C. C.; Driessen, B.
Publisher
Elsevier Inc., Philadelphia, USA
Citation
Clinical Techniques in Equine Practice, 2007, 6, 2, pp 145-153

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