Background: Bullous amyloidosis is a rare disease in humans that has not been described in a veterinary species in the peer-reviewed literature. The human disease is characterised by haemorrhagic vesicles and bullae on the skin and mucosae, which form due to amyloid deposition....

A 15-year-old Warmblood gelding was referred to the clinic because of abdominal discomfort. One year before clinical evaluation, the horse presented with a mass in the back muscles that had first appeared 3 years prior. The mass, located in the caudal saddle position, was of an unknown cause and...

A 3-year-old Arabian stallion presented for imaging and further work-up of nasal discharge and respiratory stridor secondary to nasal amyloidosis. Thickening of the nasal mucosa with heterogeneous attenuation of the affected tissues was identified on CT images. The nasal mucosa, mucosa of the...

A 9-year-old Saddlebred gelding was referred to the University of Wisconsin Veterinary Care for decreased energy levels, weight loss, persistently elevated liver enzymes, hyperglobulinaemia and leukocytosis. Abdominal ultrasonography showed a large volume of peritoneal fluid of mixed echogenicity,...

Hyperimmunization of horses with specific antigens to harvest antisera is associated with high incidence of liver amyloidosis. The histopathologic examination is the gold standard method for diagnosis of the hepatic amyloidosis. The aim of the present study was to determine whether the clinical...

Rapid, accurate detection of serum amyloid A (SAA) is needed in equine practice. We validated a patient-side point-of-care (POC) assay (Stablelab; Zoetis) compared to the turbidimetric immunoassays LZ-SAA (TIA-Hum) and VET-SAA (TIA-Vet; both Eiken Chemical). Analytical performance was assessed at 3 ...

The production of hyperimmune serum is a fundamental step in the combat and treatment of diseases caused by toxins and poisons made by virus, bacteria, or venomous animals. Usually, the species used in this activity is equine (Equus caballos) due to the docility and high capacity of serum...

Localized nasal, conjunctival and corneal amyloidosis was diagnosed in a 15-year-old pony with nasal and conjunctival masses and severe dyspnoea. Multiple swellings had been evident in the nostrils for at least two years and had gradually increased in size before presentation due to dyspnoea and...

Systemic diseases with cutaneous expression, which affect horses, are numerous but rare and of very diverse origins. This article describes the epidemiological and clinical aspects of several diseases found in equine dermatology classified by the type of dominant lesion: disorders characterized by...

Amyloidosis is a disease caused by the deposition of amorphous extracellular protein, leading to impaired kidney function. Canine and feline amyloidosis is associated with the deposition of AA protein. The disease is hereditary and is related to breed but not sex. Predisposed breeds include the...