Background: Intestinal absorption of hypoglycin A (HGA) and its metabolism are considered major prerequisites for atypical myopathy (AM). The increasing incidence and the high mortality rate of AM urgently necessitate new therapeutic and/or preventative approaches. Objectives: To identify a...

A 26-year-old pony mare (ca. 180 kg bodyweight) was presented as an emergency because it had erroneously received 110 times its standard dose of pergolide (Prascend) per os approximately 4 hours earlier. Clinical examination initially was normal except tachycardia of 52 beats/min. The pony was...

Zinc phosphide is a grey crystalline powder used as a rodenticide. Under wet or acidic conditions zinc phosphide degrades into phosphine gas. We describe clinical findings and pathology in 24 horses during 4 outbreaks of Zinc Phosphide poisoning over a period of 16 years. All horses exhibited...

Hypoglycin A (HGA) and its metabolites have been associated with equine atypical myopathy (AM). AM is often fatal and can be treated solely symptomatically. Intestinal absorption of HGA was already investigated. After absorption and metabolism of HGA, biochemical modification is triggered similarly ...

In November 2018, a horse owner from the Czech Republic experienced the loss of two of his stallions in consequence of probable poisoning. The affected animals were kept in the stable only. The mares, which were grazing on pasture during the day, were not affected. All the animals were fed the same ...

Eleven farmers from seven different locations in Distrito Federal, Midwestern Brazil, reported sudden clinical signs in 27 horses after the ingestion of commercial pelleted ration. It was found that the ration brand and batches were identical, and macroscopic evaluation revealed no abnormalities...

OBJECTIVE: To compare the effect of multiple wound dressings on microbial growth in a perfused equine wound model. SAMPLE: Abdominal musculocutaneous flaps from 16 equine cadavers. PROCEDURES: 8 full-thickness skin wound covered were created in each flap. Tissues were perfused with saline (0.9%...

The aim of this review is to establish the best therapy for equine atypical myopathy with a view to improving the survival rate. To this end, the currently used symptomatic therapy and literature on other metabolic diseases in horses or other animals have been analysed. The best treatment strategy...

Background: The efficacy of orally administered therapeutics for the treatment of cantharidin intoxication has not been evaluated in controlled studies. Objective: To develop a model of acute cantharidin intoxication in laboratory rats and to evaluate in this model the relative efficacy of 3...

A 3-month-old Criollo foal admitted to the Hospital of Veterinary Clinics of UFPel with history of tachycardia, dyspnoea, hyperthermia, mild bilateral nasal mucopurulent secretion and bilateral pulmonary rattling sounds is reported. Complete blood count revealed hyperfibrinogenaemia, leukocytosis...