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VetMed Resource

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Abstract

Reasons for performing study: In clinical practice, veterinarians often depend on owner-reported signs to assess the clinical course of horses with recurrent airway obstruction (RAO). Objectives: To test whether owner-reported information on frequency of coughing and observation of nasal discharge...

Author(s)
Rettmer, H.; Hoffman, A. M.; Lanz, S.; Oertly, M.; Gerber, V.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Equine Veterinary Journal, 2015, 47, 3, pp 291-295
Abstract

Background: It is often assumed that horses with mild respiratory clinical signs, such as mucous nasal discharge and occasional coughing, have an increased risk of developing recurrent airway obstruction (RAO). Hypothesis: Compared to horses without any clinical signs of respiratory disease, those...

Author(s)
Bosshard, S.; Gerber, V.
Publisher
Wiley-Blackwell, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2014, 28, 2, pp 618-623
Abstract

There are anecdotal reports of a beneficial effect of intravenous sodium iodide on airway mucus accumulation and inflammation in coughing horses. To our knowledge no controlled studies exist, however. Therefore, we tested the hypothesis that a single treatment with intravenous sodium iodide...

Author(s)
Ritgen, S. von; Gerber, V.
Publisher
Hippiatrika Verlagsgesellschaft mbH, Stuttgart, Germany
Citation
Pferdeheilkunde, 2010, 26, 2, pp 239-244
Abstract

Reasons for performing study: Efficacy of medications for recurrent airway obstruction is typically tested using clinical, cytological and lung function examinations of severely affected animals. These trials are technically challenging and may not adequately reflect the spectrum of disease and...

Author(s)
Gerber, V.; Schott, H. C., II; Robinson, N. E.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Equine Veterinary Journal, 2011, 43, 2, pp 153-158
Abstract

Reasons for performing study: The horse owner assessed respiratory signs index (HOARSI-1-4, healthy, mildly, moderately and severely affected, respectively) is based on owner-reported clinical history and has been used for the investigation of recurrent airway obstruction (RAO) genetics utilising...

Author(s)
Laumen, E.; Doherr, M. G.; Gerber, V.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Equine Veterinary Journal, 2010, 42, 2, pp 142-148
Abstract

Recurrent airway obstruction (RAO), or heaves, is a naturally occurring asthma-like disease that is related to sensitisation and exposure to mouldy hay and has a familial basis with a complex mode of inheritance. A genome-wide scanning approach using two half-sibling families was taken in order to...

Author(s)
Swinburne, J. E.; Bogle, H.; Klukowska-Rötzler, J.; Drögemüller, M.; Leeb, T.; Temperton, E.; Dolf, G.; Gerber, V.
Publisher
Springer-Verlag, New York, USA
Citation
Mammalian Genome, 2009, 20, 8, pp 504-515
Abstract

Background: Environment and genetics influence the manifestation of recurrent airway obstruction (RAO), but the associations of specific factors with mild, moderate, and severe clinical signs are unknown. Hypothesis: We hypothesized that sire, feed, bedding, time outdoors, sex, and age are...

Author(s)
Ramseyer, A.; Gaillard, C.; Burger, D.; Straub, R.; Jost, U.; Boog, C.; Marti, E.; Gerber, V.
Publisher
American College of Veterinary Internal Medicine, Lakewood, USA
Citation
Journal of Veterinary Internal Medicine, 2007, 21, 1, pp 149-156
Abstract

Reasons for study: Equine recurrent airway obstruction (RAO) is probably dependent on a complex interaction of genetic and environmental factors and shares many characteristic features with human asthma. Interleukin 4 receptor a chain (IL4RA) is a candidate gene because of its role in the...

Author(s)
Jost, U.; Klukowska-Rötzler, J.; Dolf, G.; Swinburne, J. E.; Ramseyer, A.; Bugno, M.; Burger, D.; Blott, S.; Gerber, V.
Publisher
Equine Veterinary Journal Ltd, Newmarket, UK
Citation
Equine Veterinary Journal, 2007, 39, 3, pp 236-241

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