An adult male guinea pig (Cavia porcellus) with a 1-month history of hind limb paresis, torticollis, and seizures was euthanized and submitted for necropsy. Gross examination was unremarkable, but histologic examination revealed multifocal eosinophilic and lymphoplasmacytic choriomeningitis and...

The neuropathologic mechanisms after exposure to lethal doses of nerve agent are complex and involve multiple biochemical pathways. Effective treatment requires drugs that can simultaneously protect by reversible binding to the acetylcholinesterase (AChE) and blocking cascades of seizure related...

Context. Human butyrylcholinesterase (huBuChE) has potential utility as a post-exposure therapy following percutaneous nerve agent poisoning as there is a slower absorption of agent by this route and hence a later onset of poisoning. Methods. We used surgically implanted radiotelemetry devices to...

Seizures and status epilepticus, which may contribute to brain injury, are common consequences of exposure to organophosphorus (OP) cholinesterase inhibitors. Effective management of these seizures is critical. To investigate the efficacy of nasal midazolam as an anticonvulsive treatment for OP...

The pharmacological screening of aqueous extract of C. infortunatum for maximal electroshock (MES) and pentylene tetrazole seizure (PTZ), Force Locomotor Activity (FLA), Conditioned Avoidance Response (CAR), analgesic activity in albino rats and local anaesthetic effect in guinea pigs were...

Scopolamine (SCP) is an anticholinergic drug used clinically for decades to treat motion sickness, as a surgical preanesthetic, and as a smooth muscle antispasmodic. It has also been used experimentally as a pretreatment and/or treatment adjunct to mitigate the toxic sequelae of organophosphorus...

This article describes the suspected adverse drug reactions in horses, cattle, swine, sheep and goats reported by Swedish veterinarians during 2007 and 2008. In coming articles the adverse reactions reported in dog, cat, rabbit and guinea pig and human reactions to veterinary drugs, will be...

The causes, diagnosis, treatment and control of skin diseases affecting rabbits and rodents were discussed.

Blackwell's Five-Minute Veterinary Consult: Small Mammal, Second Edition, brings together a wide range of information on diseases commonly seen in small exotic mammals into a single, accessible resource. With consistency and broad coverage unparalleled by other texts, this new edition adds sections ...

Neurocysticercosis (NCC) caused by the larval stage of Taenia solium was recognized in Paniai District, western Irian Jaya Province, Indonesia, in the early 1970s. In the 1990s, a rapid increase in the number of cases of epileptic seizures and burns was observed in Assologaima Sub-District,...