Cookies on VetMed Resource

Like most websites we use cookies. This is to ensure that we give you the best experience possible.

 

Continuing to use www.cabi.org  means you agree to our use of cookies. If you would like to, you can learn more about the cookies we use.

VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

Sign up to start receiving our Veterinary & Animal Sciences e-newsletter, book alerts and offers direct to your inbox.

Results per page:

Search results

Abstract

Organophosphorus compounds (OPs) include nerve agents and insecticides that potently inhibit acetylcholinesterase (AChE), an essential enzyme found throughout the nervous system. High exposure levels to OPs lead to seizures, cardiac arrest, and death if left untreated. Oximes are a critical piece...

Author(s)
Nichols, R. H.; Chambers, J. E.
Publisher
Elsevier Ireland, Shannon, Irish Republic
Citation
Toxicology, 2021, 452,
AbstractFull Text

The purpose of the research is to study the cumulative properties of the long-acting preparation "Flyblock insecticidal tag". Materials and methods. The cumulative properties of the "Flyblock insecticidal tag" preparation were studied by the subchronic toxicity method on 20 male guinea pigs, which...

Author(s)
Mironenko, A. V.
Publisher
All-Russian K. I. Skryabin Scientific Research Institute of Helminthology, Moscow, Russia
Citation
Rossiiskii Parazitologicheskii Zhurnal, 2020, 3, pp 99-103
Abstract

An adult male guinea pig (Cavia porcellus) with a 1-month history of hind limb paresis, torticollis, and seizures was euthanized and submitted for necropsy. Gross examination was unremarkable, but histologic examination revealed multifocal eosinophilic and lymphoplasmacytic choriomeningitis and...

Author(s)
Southard, T.; Bender, H.; Wade, S. E.; Grunenwald, C.; Gerhold, R. W.
Publisher
American College of Veterinary Pathologists Inc., Lawrence, USA
Citation
Veterinary Pathology, 2013, 50, 3, pp 560-562
Abstract

The neuropathologic mechanisms after exposure to lethal doses of nerve agent are complex and involve multiple biochemical pathways. Effective treatment requires drugs that can simultaneously protect by reversible binding to the acetylcholinesterase (AChE) and blocking cascades of seizure related...

Author(s)
Wang, Y.; Wei, Y. L.; Oguntayo, S.; Doctor, B. P.; Nambiar, M. P.
Publisher
Elsevier Science Ireland Ltd., Shannon, Irish Republic
Citation
Chemico-Biological Interactions, 2013, 203, 1, pp 120-124
Abstract

Seizures and status epilepticus, which may contribute to brain injury, are common consequences of exposure to organophosphorus (OP) cholinesterase inhibitors. Effective management of these seizures is critical. To investigate the efficacy of nasal midazolam as an anticonvulsive treatment for OP...

Author(s)
Gilat, E.; Goldman, M.; Lahat, E.; Levy, A.; Rabinovitz, I.; Cohen, G.; Brandeis, R.; Amitai, G.; Alkalai, D.; Eshel, G.
Publisher
Springer-Verlag, Berlin, Germany
Citation
Archives of Toxicology, 2003, 77, 3, pp 167-172
Abstract

Context. Human butyrylcholinesterase (huBuChE) has potential utility as a post-exposure therapy following percutaneous nerve agent poisoning as there is a slower absorption of agent by this route and hence a later onset of poisoning. Methods. We used surgically implanted radiotelemetry devices to...

Author(s)
Mumford, H.; Price, M. E.; Lenz, D. E.; Cerasoli, D. M.
Publisher
Informa Healthcare, London, UK
Citation
Clinical Toxicology, 2011, 49, 4, pp 287-297
AbstractFull Text

The pharmacological screening of aqueous extract of C. infortunatum for maximal electroshock (MES) and pentylene tetrazole seizure (PTZ), Force Locomotor Activity (FLA), Conditioned Avoidance Response (CAR), analgesic activity in albino rats and local anaesthetic effect in guinea pigs were...

Author(s)
Kumari, M.; Prasad, R.; Roy, B. K.
Publisher
Indian Association for the Advancement of Veterinary Research, Bareilly, India
Citation
Indian Journal of Veterinary Research, 2008, 17, 2, pp 25-31
Abstract

Scopolamine (SCP) is an anticholinergic drug used clinically for decades to treat motion sickness, as a surgical preanesthetic, and as a smooth muscle antispasmodic. It has also been used experimentally as a pretreatment and/or treatment adjunct to mitigate the toxic sequelae of organophosphorus...

Author(s)
Koplovitz, I.; Schulz, S.
Publisher
Association of Military Surgeons of the US, Bethesda, USA
Citation
Military Medicine, 2010, 175, 11, pp 878-882
AbstractFull Text

The causes, diagnosis, treatment and control of skin diseases affecting rabbits and rodents were discussed.

Author(s)
White, S.
Publisher
World Small Animal Veterinary Association, Bangkok, Thailand
Citation
40th World Small Animal Veterinary Association Congress, Bangkok, Thailand, 15-18 May, 2015. Proceedings book, 2015, pp 485-487
Abstract

This article describes the suspected adverse drug reactions in horses, cattle, swine, sheep and goats reported by Swedish veterinarians during 2007 and 2008. In coming articles the adverse reactions reported in dog, cat, rabbit and guinea pig and human reactions to veterinary drugs, will be...

Author(s)
Tjälve, H.
Publisher
Sveriges Veterinärförbund, Stockholm, Sweden
Citation
Svensk Veterinärtidning, 2009, 61, 13, pp 11-19

Refine Results

Sort Order
Author
Geographical Location
Item Type
Language
Organisms
Subject Topics