A 3-year-old female intact guinea pig (Cavia porcellus) was presented for torticollis and ocular discharge. On examination, the guinea pig had a left head tilt with corneal ulceration and absent palpebral response of the right eye. Computed tomography showed a soft tissue attenuating mass with...

An adult male guinea pig (Cavia porcellus) with a 1-month history of hind limb paresis, torticollis, and seizures was euthanized and submitted for necropsy. Gross examination was unremarkable, but histologic examination revealed multifocal eosinophilic and lymphoplasmacytic choriomeningitis and...

Case Description: A 5-year-old male guinea pig (Cavia porcellus) was examined because of lethargy, weight loss, and episodic neurologic signs, including paddling in lateral recumbency, head tilt, and circling. Prior to initial examination, the animal was treated with corn syrup whenever it appeared ...

Objectives: Mouse models have delivered variable recapitulation of Kyasanur Forest disease (KFD) pathology and consistently demonstrated neurological involvement which may be a limited feature of human disease. With the purpose of more accurately modelling human disease progression we infected...

This paper describes an insulinoma in 2 guinea pigs (Cavia porcellus). Both guinea pigs presented with neurologic signs and low blood glucose readings. The neurologic signs resolved with dextrose administration. Insulinoma was confirmed on postmortem examination.

L3 larvae of Elaphostrongylus cervi, originating from red deer (Cervus elaphus), first reached the central nervous system (CNS) of guinea pigs (Cavia porcellus) at 11 days postinfection (DPI). Neurological signs were seen between 11 and 62 DPI in 4 of 18 infected guinea pigs killed up to 112 DPI....

Bilateral hindlimb paresis occurred in 3 guineapigs in Tennessee, USA, after immunization with an adjuvant-antigen mixture containing complete Freund's adjuvant [date not given]. Doses were injected into unanaesthetized animals, divided among 3 or 4 sites and given slightly off midline in the...

Four guinea pigs from a laboratory colony of approximately 50 animals were examined for the cause of a progressive neurological disease of 5 days duration; 26 additional animals from the same colony also developed symptoms. Signs of neurological dysfunction included cachexia, stupor,...

Tunicamycin was administered to 8-week-old guineapigs (n=12) by a single subcutaneous injection of 400 µg/kg in physiological saline, within 1 h of preparation based on a published method. Six control animals were injected with a similar volume of physiological saline. Light microscopic and fine...

The clinical symptoms of infestation with Trixacarus caviae Fain, Hovell & Hyatt in guinea-pigs are described. In general large areas of thickened, denuded skin, with a heavy secondary bacterial infection, and sometimes neurological signs, are observed in mangy cases. Antiparasitic therapy was...