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Abstract

Background: The purpose of this study is to examine the use of daikenchuto (DKT), a traditional Japanese medicine, as a potential treatment for opiate-induced slowing of intestinal transit in an isolated guinea pig colon model of motility. Methods: Isolated segments of distal guinea pig colon were...

Author(s)
Wood, M. J.; Hyman, N. H.; Mawe, G. M.
Publisher
Academic Press, Orlando, USA
Citation
Journal of Surgical Research, 2010, 164, 1, pp 84-90
Abstract

Dried fruits of Piper nigrum (black pepper) are commonly used in gastrointestinal disorders. The aim of this study was to rationalize the medicinal use of pepper and its principal alkaloid, piperine, in constipation and diarrhea using in vitro and in vivo assays. When tested in isolated guinea pig...

Author(s)
Mehmood, M. H.; Gilani, A. H.
Publisher
Mary Ann Liebert, Inc., New Rochelle, USA
Citation
Journal of Medicinal Food, 2010, 13, 5, pp 1086-1096
Abstract

The effect of mitragynine, an indole alkaloid isolated from the Thai medicinal plant kratom (M. speciosa), on electrically stimulated contraction was studied in the guineapig ileum. Mitragynine (1 nsmallcap˜M - 3 µsmallcap˜M) inhibited the contraction elicited by electrical stimulation, and its pD2 ...

Author(s)
Watanabe, K.; Yano, S.; Horie, S.; Yamamoto, L. T.
Citation
Life Sciences, 1997, 60, 12, pp 933-942
Abstract

The effects of tetrandrine (Tet, from Stephania tetrandra) and nimodipine (Nim) on the morphine (Mor) withdrawal response in the isolated guineapig ileum were studied. The withdrawal contracture was elicited by addition of naloxone (Nal, 1 µmol/litre) to the isolated naive ileum incubated with Mor...

Author(s)
Liu ZhongHua; Li JinLian; Li Na; Tian ChunLin; Zhang KaiGao
Citation
Acta Pharmacologica Sinica, 1999, 20, 11, pp 1000-1004
Abstract

Author(s)
Johnson-Delaney, C.
Publisher
Zoological Education Network, Lake Worth, USA
Citation
Exotic DVM, 2004, 6, 4, pp 18
Abstract

Dosage was 0.05 mg fentanyl, 2 mg climazolam and 2 mg xylazine per kg body weight, by i.m. injection. Anaesthesia was terminated by an i.v. injection (into a subcutaneous abdominal vein close to the manubrium) of 0.03 mg naloxone, 0.3 mg sarmazenil and 2 mg yohimbine per kg body weight.

Author(s)
Henke, J.; Roberts, U.; Otto, K.; Lendl, C.; Matis, U.; Brill, T.; Erhardt, W.
Citation
Tierärztliche Praxis, 1996, 24, 1, pp 85-87
Abstract

Retro-nociceptin methylester (retro-Noc-ME), which has an oppositely directed structure to that of nociceptin, showed weak affinity for nociceptin receptor and antagonized nociceptin-induced inhibition of contraction in a guinea pig ileum (GPI) assay. The peptide induced analgesia after...

Author(s)
Jinsmaa, Y.; Takahashi, M.; Fukunaga, H.; Yoshikawa, M.
Publisher
Elsevier Science Inc., New York, USA
Citation
Life Sciences, 2000, 67, 25, pp 3095-3101
Abstract

The purpose of this study was to determine whether β-lactotensin (BLT), a bioactive peptide, was released from bovine β-lactoglobulin (β-Lg) by in vitro proteolysis using bovine β-chymotrypsin, porcine pepsin or bovine trypsin. β-Lg f(146-149) (His-Ile-Arg-Leu) was formed during hydrolysis with...

Author(s)
Pihlanto-Leppälä, A.; Paakkari, I.; Rinta-Koski, M.; Antila, P.
Citation
Journal of Dairy Research, 1997, 64, 1, pp 149-155
Abstract

The influence of β-casomorphin-5 on the β-adrenoceptor complex in guineapig heart membranes was investigated by means of binding studies, G-protein investigations and isolated heart preparations. In nanomolar concn. β-CM-5 induced an increase in receptor affinity towards the agonist isoproterenol...

Author(s)
Liebmann, C.; Mentz, P.; Schnittler, M.; Schrader, U.; Neubert, K.; Barth, A.
Citation
Peptides, 1991, 12, 2, pp 265-270
Abstract

B. serraefolia is widely used in Mexican traditional medicine to treat diarrhoea. Although the methanolic extract of this plant has shown an important dose-dependent spasmolytic activity, its underlying mechanism has not been studied. In the present work, the methanolic extract of B. serraefolia...

Author(s)
Tortoriello, J.; Aguilar-Santamaría, L.
Citation
Journal of Ethnopharmacology, 1996, 53, 3, pp 157-163

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