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Abstract

It is known that there is an age-related increase in gastrointestinal diseases. However, there is a lack of studies dealing with the correlation between age-related changes in function and intrinsic innervation in the gastrointestinal tract. The purpose of this work was to study this subject in the ...

Author(s)
Abalo, R.; Vera, G.; Rivera, A. J.; Martín, M. I.
Publisher
Elsevier, New York, USA
Citation
Life Sciences, 2007, 80, 26, pp 2436-2445
Abstract

Previous studies on the aflatoxins have focused mainly on their chronic toxic effects. In this study we investigated the acute gastrointestinal effects of four common aflatoxins on isolated guinea pig ileum. AFB1 (EC50 4.6±0.4 µM) and AFB2 (EC50 17±4.4 µM) contracted isolated guinea pig ileum in a...

Author(s)
Luzi, A.; Cometa, M. F.; Palmery, M.
Publisher
Elsevier Science Ltd, Oxford, UK
Citation
Toxicology in Vitro, 2002, 16, 5, pp 525-529
Abstract

Author(s)
Mancinelli, E.
Publisher
Veterinary Business Development Ltd, Peterborough, UK
Citation
VN Times, 2011, 11, 11, pp 22...25
Abstract

Treatment with morphine causes a reduction in non-protein sulfhydryl content in the liver because the morphine metabolite, morphonine, conjugates with sulfhydryl compounds. Ginseng [Panax] saponins inhibited morphine 6-dehydrogenase (from guinea-pig liver), which catalyses the production of...

Author(s)
Kim HackSeang; Jeong InSook
Citation
Korean Journal of Pharmacognosy, 1994, 25, 2, pp 160-166
Abstract

The effects of tetrandrine (Tet, from Stephania tetrandra) and nimodipine (Nim) on the morphine (Mor) withdrawal response in the isolated guineapig ileum were studied. The withdrawal contracture was elicited by addition of naloxone (Nal, 1 µmol/litre) to the isolated naive ileum incubated with Mor...

Author(s)
Liu ZhongHua; Li JinLian; Li Na; Tian ChunLin; Zhang KaiGao
Citation
Acta Pharmacologica Sinica, 1999, 20, 11, pp 1000-1004
Abstract

The effect of mitragynine, an indole alkaloid isolated from the Thai medicinal plant kratom (M. speciosa), on electrically stimulated contraction was studied in the guineapig ileum. Mitragynine (1 nsmallcap˜M - 3 µsmallcap˜M) inhibited the contraction elicited by electrical stimulation, and its pD2 ...

Author(s)
Watanabe, K.; Yano, S.; Horie, S.; Yamamoto, L. T.
Citation
Life Sciences, 1997, 60, 12, pp 933-942
Abstract

The antitussive-expectorant effects of two phytotherapeutic formulations sold in the Brazilian market were evaluated using three different biological models. Each phytotherapeutic formulation, with different composition, had the same batch number and fabrication date. The trade names of the...

Author(s)
Mello, F. B. de; Mello, J. R. B. de
Publisher
Universidade Federal do Rio Grande do Sul, Faculdade de Veterinária, Porto Alegre, Brazil
Citation
Acta Scientiae Veterinariae, 2005, 33, 2, pp 161-167
Abstract

This study investigated some pharmacological properties of methanolic extract of Palisota hirsuta Reichb. ex Endl (Commelinaceae) leaves using in vitro and in vivo methods. Acute toxicity study of the extract gave an oral LD50 of 260.6 mg/kg, b.w. in fasted mice. Oral administration of the extract...

Author(s)
Anaga, A. O.; Eke, I. G.; Chah, K. F.
Publisher
Faculty of Veterinary Medicine, Ibadan, Nigeria
Citation
Tropical Veterinarian, 2009, 27, 4, pp 37-47
Abstract

The effects of extracts, chromatographic fractions, and pure compounds from aerial parts of Z. gaetulum (collected from Morocco in 1992) were investigated against electrically-induced contractions of isolated guineapig ileum and morphine withdrawal in vitro. All extracts and partially purified...

Author(s)
Capasso, A.; Omar, S.; Fkih-Tetouani, S.; Sorrentino, L.; Aquino, R.
Citation
Pharmaceutical Biology, 1998, 36, 5, pp 320-326
Abstract

The effect of 4 flavonol glycosides isolated from aerial parts of C. menthodorus [C. menthodorum], collected from Ecuador in 1993, on in vitro morphine withdrawal in guineapigs was investigated. All flavonol glycosides (1 × 10-7, 1 × 10-6 and 1 × 10-5 smallcap˜M), administered 10 min before ...

Author(s)
Capasso, A.; Piacente, S.; Cumandà, J.; Tommasi, N. de; Ragucci, M.; Pizza, C.
Citation
Pharmaceutical Biology, 1998, 36, 5, pp 310-314

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