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Abstract

Squamous cell carcinoma is the most common malignant oral tumor in cats. The late presentation is one of the factors contributing to the detrimental prognosis of this disease. The immunohistochemical expression of the p53 tumor suppressor protein has been reported in 24% to 65% of feline oral ...

Author(s)
Renzi, A.; Bonis, P. de; Morandi, L.; Lenzi, J.; Tinto, D.; Rigillo, A.; Bettini, G.; Bellei, E.; Sabattini, S.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2019, 14, 4, pp e0215621
Abstract

Oral squamous cell carcinoma is an aggressive tumor in cats; however, molecular-targeted therapies against this tumor, including antibody therapy, have not been developed. Sensitive and specific monoclonal antibodies (mAbs) against highly expressed membrane proteins are needed to develop antibody...

Author(s)
Itai, S.; Yamada, S.; Kaneko, M. K.; Harada, H.; Kagawa, Y.; Konnai, S.; Kato, Y.
Publisher
Mary Ann Liebert, Inc., New Rochelle, USA
Citation
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, 2017, 36, 6, pp 243-250
AbstractFull Text

Squamous cell carcinoma (SCC), also known as squamous cell carcinoma, squamous cell carcinoma or squamous cell carcinoma, is a cutaneous malignant neoplasm that appears frequently in felines, presenting in this species a distinct behavior of the other species. Prolonged exposure to ultraviolet (UV) ...

Author(s)
Santos, N. N. dos; Pereira, L. B. de S. B.; Fonseca Filho, L. B. da; Carvalho, A. J. de; Pontes, M. B.; D'Alcantara, N. de A. L. G.; Bessa, A. L. N. G.; Albuquerque, P. V. de; Nascimento, J. C. dos S.; Souza, W. M. A. de
Publisher
Pubvet, Maringá, Brazil
Citation
PUBVET, 2018, 12, 7, pp 1-12
Abstract

Squamous cell carcinoma is the most common oral cancer in the cat and presents as a locally aggressive lesion for which an effective therapeutic protocol remains elusive. Feline oral squamous cell carcinoma (OSCC) shares many clinical characteristics with human head and neck squamous cell carcinoma ...

Author(s)
Sparger, E. E.; Murphy, B. G.; Kamal, F. M.; Arzi, B.; Naydan, D.; Skouritakis, C. T.; Cox, D. P.; Skorupski, K.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2018, 202, pp 52-62
Abstract

Feline oral squamous cell carcinoma (FOSCC) is a highly aggressive head and neck cancer in cats, but the molecular pathogenesis of this cancer is still uncertain. In this study, p16, p53, and pRb proteins were detected and quantified by immunohistochemistry in forty-three FOSCC primary tumors and...

Author(s)
Supsavhad, W.; Dirksen, W. P.; Hildreth, B. E., III; Rosol, T. J.
Publisher
MDPI AG, Basel, Switzerland
Citation
Veterinary Sciences, 2016, 3, 3, pp 18
AbstractFull Text

Squamous cell carcinoma is a malignant neoplasm arising from cells of the squamous epithelium, consisting of the most common type of skin tumor in felines, where solar radiation is the contributory factor in cats with light or depigmented skin. The objective of this work was to report a case of ...

Author(s)
Melo, A. M. C. de; Cardoso, T. M. S.; Cruz, M. V. R. A.; Oliveira, C. A. A. de; Vital, K. C.; Pastl, R. M.; Carvalho, K. dos S.
Publisher
Pubvet, Maringá, Brazil
Citation
PUBVET, 2018, 12, 9, pp 1-6
Abstract

Oral squamous cell carcinoma (OSCC) is an aggressive and treatment-resistant malignancy in both feline and human patients. Recent work has demonstrated aberrant expression of fatty acid synthase (FASN) and an increased capacity for lipogenesis in human OSCC and other cancers. In human OSCC,...

Author(s)
Walz, J. Z.; Saha, J.; Arora, A.; Khammanivong, A.; O'Sullivan, M. G.; Dickerson, E. B.
Publisher
Wiley, Oxford, UK
Citation
Veterinary and Comparative Oncology, 2018, 16, 1, pp E99-E108
Abstract

Although oral squamous cell carcinomas (SCCs) are common in cats there are currently few prognostic markers for these cancers. This study used 52 feline oral SCCs to determine if prognosis can be predicted by the age or sex of the cat, the presence of bone within the diagnostic sample, or the...

Author(s)
Munday, J. S.; He YanYu; Aberdein, D.; Klobukowska, H. J.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Journal, 2019, 248, pp 64-70
Abstract

OBJECTIVE: To investigate protein kinase CK2 (CK2) expression in squamous cell carcinoma (SCC) of cats and to examine effects of CK2 downregulation on in vitro apoptosis and viability in SCC. SAMPLE: Biopsy specimens of oral mucosa and testis and blood samples from clinically normal cats, biopsy...

Author(s)
Cannon, C. M.; Trembley, J. H.; Kren, B. T.; Unger, G. M.; O'Sullivan, M. G.; Cornax, I.; Modiano, J. F.; Ahmed, K.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2017, 78, 8, pp 946-953
Abstract

Objectives: The aim of the study was to determine the clinical benefit and adverse event profile of toceranib phosphate in the treatment of feline oral squamous cell carcinoma (FOSCC). Methods: Data obtained from the medical records of cats with oral squamous cell carcinoma diagnosed between 2010...

Author(s)
Wiles, V.; Hohenhaus, A.; Lamb, K.; Zaidi, B.; Camps-Palau, M.; Leibman, N.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Journal of Feline Medicine and Surgery, 2017, 19, 2, pp 185-193

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