Objectives: To determine response rates, median progression free survival (PFS) and survival times (MST) for cats with intermediate-large cell lymphoma treated with a CMOP protocol. Methods: Medical records of 31 cats treated between 2009-2022 were reviewed. Cats were included in the study if they...
Author(s)
Webster, J.; Morris, J.; McNaught, K.
Publisher
British Small Animal Veterinary Association (BSAVA), Quedgeley, UK
Citation
BSAVA Congress Proceedings 2023, 2023,
Objectives: The purpose of this study was to investigate the disease-free interval, survival time and adverse events of a combined treatment approach in cats with mammary malignant tumors using radical mastectomy and adjuvant mitoxantrone. Methods: All cats underwent surgery to remove the mammary...
Author(s)
Cunha, S. C. S.; Corgozinho, K. B.; Souza, H. J. M.; Silva, K. V. G. C.; Ferreira, A. M. R.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Journal of Feline Medicine and Surgery, 2015, 17, 12, pp 1000-1004
ABCG2 (ATP binding cassette subfamily G, member 2) mediates resistance to a variety of cytotoxic agents. Although human ABCG2 is well characterized, the function of canine ABCG2 has not been studied previously. Feline ABCG2 has an amino acid substitution in the adenosine triphosphate-binding domain ...
Author(s)
Lewis, R. S.; Fidel, J.; Dassanayake, S.; Court, M. H.; Burke, N. S.; Mealey, K. L.
Publisher
Wiley, Oxford, UK
Citation
Veterinary and Comparative Oncology, 2017, 15, 2, pp 411-420
Objectives: Distribution of fluoroquinolones to the retina is normally restricted by ABCG2 at the blood-retinal barrier. As the cat develops a species-specific adverse reaction to photoreactive fluoroquinolones, our goal was to investigate ABCG2 as a candidate gene for fluoroquinolone-induced...
Author(s)
Ramirez, C. J.; Minch, J. D.; Gay, J. M.; Lahmers, S. M.; Guerra, D. J.; Haldorson, G. J.; Schneider, T.; Mealey, K. L.
Publisher
Lippincott Williams & Wilkins, Inc., Hagerstown, USA
Citation
Pharmacogenetics and Genomics, 2011, 21, 2, pp 66-75
A 10-year-old female desexed domestic shorthair cat was diagnosed by the regular veterinarian with large cell splenic lymphoma in June 2020. A splenectomy was performed; however, complications postoperatively and the owner's willingness to pursue chemotherapy resulted in the patient being referred...
Author(s)
Herbert, J.; Todd, J.; Leeder, D.
Publisher
Wiley, Chichester, UK
Citation
Veterinary Record Case Reports, 2022, 11, 1,
The present case describes the treatment of a mucoepidermoid carcinoma in a 13-year-old female sterilized European domestic cat, using lung lobectomy and accompanying mitoxantrone chemotherapy. Six, 14, 19 and 27 months after the initial treatment tomodensitometric and radiographic examinations...
Author(s)
Lamolet, R.; Manassero, M.; Reyes-Gomez, E.; Béguin, J.
Publisher
Gesellschaft Schweizer Tierärztinnen und Tierärzte GST, Bern, Switzerland
Citation
SAT, Schweizer Archiv für Tierheilkunde, 2021, 163, 4, pp 295-300
The purpose of this retrospective case series was to investigate the delayed acute effects of chemotherapy drugs in cats receiving cancer treatment. Medical records were reviewed to determine the chemotherapy agent used and delayed adverse effects. Side effects were classified according to...
Author(s)
Cunha, S. C. dos S.; Silva, F. B.; Corgozinho, K. B.; Silva, K. V. G. C. da; Ferreira, A. M. R.
Publisher
Universidade Federal do Rio Grande do Sul, Faculdade de Veterinária, Porto Alegre, Brazil
Citation
Acta Scientiae Veterinariae, 2018, 46, pp 1520
Background: Quality of life (QoL) is an essential factor in therapeutic decision-making for human patients and is commonly used as an endpoint in clinical trials of cancer treatments. Aim: To compare owners' perception of QoL in canine and feline patients affected by different tumor histotypes...
Author(s)
Bianchi, M. L.; Drudi, D.; Treggiari, E.; Catalucci, C.; Attorri, V.; Bonazzi, I.; Valenti, P.
Publisher
Faculty of Veterinary Medicine, University of Tripoli, Tripoli, Libya
Citation
Open Veterinary Journal, 2021, 11, 4, pp 755-763
Tumour specimens from two cats undergoing surgery for removal of vaccine-associated sarcomas were minced and treated with trypsin under aseptic conditions to obtain single-cell suspensions, which were then cultured in vitro in medium supplemented with 5% heat-inactivated fetal bovine serum. Two...
Author(s)
Williams, L. E.; Banerji, N.; Klausner, J. S.; Kapur, V.; Kanjilal, S.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2001, 62, 9, pp 1354-1357
Eighty-seven cats with histologically confirmed malignant tumours were used in a prospective study determining that administration of mitoxantrone is associated with minimal toxicoses when administered at 21-day intervals at dosages ranging from 2.5 to 6.5 mg/m2 of body surface i.v. In this study,...
Author(s)
Ogilvie, G. K.; Moore, A. S.; Obradovich, J. E.; Elmslie, R. E.; Vail, D. M.; Straw, R. C.; Salmon, M. D.; Klein, M. K.; Atwater, S. W.; Ciekot, P. E.; LaRue, S. M.; Peaston, A.; Withrow, S. J.
Citation
Journal of the American Veterinary Medical Association, 1993, 202, 11, pp 1839-1844