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Abstract

Background: Insulinoma is an autonomous insulin-secreting islet cell neoplasm that is rarely diagnosed in cats. The clinical and pathological aspects of feline insulinoma have been described previously, but the molecular characteristics of these tumors have not been investigated. Objectives: The...

Author(s)
Jackson, T. C.; Debey, B.; Lindbloom-Hawley, S.; Jones, B. T.; Schermerhorn, T.
Publisher
Blackwell Publishing, Oxford, UK
Citation
Journal of Veterinary Internal Medicine, 2009, 23, 2, pp 383-387
Abstract

Case summary: An 11-year-old male neutered domestic shorthair cat presented with behavioural changes. Physical examination revealed bradycardia and a cranial abdominal mass. The cat was persistently hypoglycaemic (1.2 mmol/l; reference interval [RI] 3.5-5.5 mmol/l) with decreased fructosamine...

Author(s)
Guillen, A.; Ressel, L.; Finotello, R.; German, A. J.; Freeman, A.; Blackwood, L.
Publisher
Sage Publications Ltd, London, UK
Citation
Journal of Feline Medicine and Surgery Open Reports, 2019, 5, 1, pp 32-2055116919856129
AbstractFull Text

This paper reports a necrolytic migratory erythema (NME) case with glucagonoma and diabetes mellitus (DM) by clinical, histopathological and immunohistochemical examinations. A 12-year-old cat in Brazil presented with complaints of skin lesions in the neck region, hyperglycaemia, weight loss and...

Author(s)
Sahİnduran, S.; Ozmen, O.
Publisher
Universidade Federal do Rio Grande do Sul, Faculdade de Veterinária, Porto Alegre, Brazil
Citation
Acta Scientiae Veterinariae, 2017, 45, Supplement, pp 223
Abstract

The expression of chromogranin A (CgA) was investigated in paraffin-embedded tissues from 25 canine and 2 feline pancreatic islet cell tumours, 5 canine and 6 feline exocrine pancreatic tumours, and normal pancreatic tissue from 2 dogs and 2 cats. Heparinized plasma samples from 3 dogs and 2 cats...

Author(s)
Myers, N. C.; Andrews, G. A.; Chard-Bergstrom, C.
Citation
American Journal of Veterinary Research, 1997, 58, 6, pp 615-620
Abstract

A functional, insulin-secreting pancreatic (islet cell) carcinoma was diagnosed in a 17-year-old male Siamese cat. Diagnosis was made on the basis of clinical signs (i.e., seizures and stupor) that resolved temporarily after correlation of hypoglycaemia with feeding or i.v. administration of...

Author(s)
Hawks, D.; Peterson, M. E.; Hawkins, K. L.; Rosebury, W. S.
Citation
Journal of Veterinary Internal Medicine, 1992, 6, 3, pp 193-196
Abstract

A 16-year-old, castrated, male, Japanese domestic cat presented with walking difficulties, while dysstasia and convulsive seizure were noted nine days after the first examination. Blood glucose had decreased severely (32 mg/d/) over this period. An insulinoma was suspected clinically, and diagnosis ...

Author(s)
Kanaya, S.; Goryo, M.; Sasaki, J.; Shishido, S.; Okada, K.
Publisher
Japan Veterinary Medical Association, Tokyo, Japan
Citation
Journal of the Japan Veterinary Medical Association, 2009, 62, 10, pp 810-814
Abstract

Pancreatic islet cell tumours (ICTs) were reported in 27 dogs and 2 cats by 11 colleges of veterinary medicine in the United States and Canada from 1964 to 1972. Tumours were excessive only in standard poodles, about equally distributed by sex, and associated with a moderately increasing risk by...

Author(s)
Priester, W. A.
Citation
Journal of the National Cancer Institute, 1974, 53, No.1, pp 227-229
Abstract

β-cell and insulin antibodies are involved in the pathogenesis of diabetes in human patients. β-cell antibodies have also been found in about 50% of newly diagnosed diabetic dogs. This study's objective was to examine these antibodies' role in feline diabetes. The serum of 26 newly diagnosed...

Author(s)
Hoenig, M.; Reusch, C.; Peterson, M. E.
Publisher
Elsevier Science B.V., Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2000, 77, 1/2, pp 93-102
Abstract

Diagnosis and treatment of APUDomas are reviewed. Insulinoma, the most common APUDoma in dogs and Zollinger-Ellison syndrome (gastric acid hypersecretion and ulceration associated with pancreatic isle cell tumour) are discussed in detail.

Author(s)
Johnson, S. E.
Citation
Seminars in Veterinary Medicine and Surgery (Small Animal), 1989, 4, 3, pp 202-211

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