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Abstract

Background: A spot-on formulation containing fluralaner (280 mg/ml) plus moxidectin (14 mg/ml) (Bravecto® Plus) was developed for the treatment of nematode infections as well as providing 12 weeks of protection against insect and acarine parasites in cats. The effectiveness and safety of this...

Author(s)
Rohdich, N.; Zschiesche, E.; Wolf, O.; Loehlein, W.; Kirkova, Z.; Iliev, P.; Rapti, D.; Postoli, R.; Capári, B.; Farkas, R.; Roepke, R. K. A.
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2018, 11, 589, pp (19 November 2018)
Abstract

Background: Troglostrongylus brevior, a lungworm usually affecting wild felids, has been recently recorded in a number of cases in domestic cats, mainly in Mediterranean areas. Although feline troglostrongylosis is a severe and life-threatening disease, especially in young cats, treatment options...

Author(s)
Traversa, D.; Veronesi, F.; Danesi, P.; Morelli, S.; Crisi, P. E.; Morganti, G.; Iorio, R.; Pampurini, F.; Schaper, R.; Santoro, A.; Paoletti, B.; Cesare, A. di
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2019, 12, 97, pp (12 March 2019)
Abstract

Background: Aelurostrongylus abstrusus is the most important nematode affecting the respiratory tract of cats in terms of prevalence and clinical relevance. The aim of this randomised controlled field study was to confirm the efficacy of the spot-on containing emodepside/praziquantel (Profender,...

Author(s)
Crisi, P. E.; Cesare, A. di; Traversa, D.; Vignoli, M.; Morelli, S.; Tommaso, M. di; Santis, F. de; Pampurini, F.; Schaper, R.; Boari, A.
Publisher
BMJ Publishing Group, London, UK
Citation
Veterinary Record, 2020, 187, 5, pp e34-e34
Abstract

Current mass drug administration (MDA) programs for the treatment of human river blindness (onchocerciasis) caused by the filarial worm Onchocerca volvulus rely on ivermectin, an anthelmintic originally developed for animal health. These treatments are primarily directed against migrating...

Author(s)
Krücken, J.; Holden-Dye, L.; Keiser, J.; Prichard, R. K.; Townson, S.; Makepeace, B. L.; Hübner, M. P.; Hahnel, S. R.; Scandale, I.; Harder, A.; Kulke, D.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS Pathogens, 2021, 17, 7,
Abstract

Filariae are parasitic nematodes that are transmitted to their definitive host as third-stage larvae by arthropod vectors like mosquitoes. Filariae cause diseases including: lymphatic filariasis with distressing and disturbing symptoms like elephantiasis; and river blindness. Filarial diseases...

Author(s)
Kashyap, S. S.; Verma, S.; Voronin, D.; Lustigman, S.; Kulke, D.; Robertson, A. P.; Martin, R. J.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS Pathogens, 2019, 15, 9, pp e1008041
AbstractFull Text

The purpose of this study was 2-fold: (1) to investigate the prevalence of gastrointestinal parasite infection in cats reared in Daegu, Republic of Korea and (2) to assess the efficacy and safety of a topical emodepside/praziquantel formulation for cats with parasitic infections. The...

Author(s)
Lee SeungHun; Ock YounSung; Choi DongHag; Kwak DongMi
Publisher
Korean Society for Parasitology and Tropical Medicine, Seoul, Korea Republic
Citation
Korean Journal of Parasitology, 2019, 57, 3, pp 243-248
Abstract

Filariae are vector-borne nematodes responsible for an enormous burden of disease. Human lymphatic filariasis, caused by Wuchereria bancrofti, Brugia malayi, and Brugia timori, and onchocerciasis (caused by Onchocerca volvulus) are neglected parasitic diseases of major public health significance in ...

Author(s)
Hübner, M. P.; Townson, S.; Gokool, S.; Tagboto, S.; Maclean, M. J.; Verocai, G. G.; Wolstenholme, A. J.; Frohberger, S. J.; Hoerauf, A.; Specht, S.; Scandale, I.; Harder, A.; Glenschek-Sieberth, M.; Hahnel, S. R.; Kulke, D.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
International Journal for Parasitology: Drugs and Drug Resistance, 2021, 17, pp 27-35
Abstract

The adulticidal efficacy of a topical combination of emodepside 2.1% (w/v) plus praziquantel 8.6% (w/v) (Profender® spot-on for cats, Bayer) against adult Aelurostrongylus abstrusus nematodes was evaluated in two randomised, placebo-controlled laboratory efficacy studies. Each study involved 16 ...

Author(s)
Böhm, C.; Wolken, S.; Schnyder, M.; Basso, W.; Deplazes, P.; Cesare, A. di; Deuster, K.; Schaper, R.
Publisher
Springer Berlin, Heidelberg, Germany
Citation
Parasitology Research, 2015, 114, Suppl. 1, pp 155-164
Abstract

The aim of this study was to sequence all exons of the ABCB1 (MDR1) gene in cats that had experienced adverse reactions to P-glycoprotein substrate drugs (phenotyped cats). Eight phenotyped cats were included in the study consisting of eight cats that experienced central nervous system toxicosis...

Author(s)
Mealey, K. L.; Burke, N. S.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2015, 38, 5, pp 429-433
Abstract

This study aimed to evaluate the efficacy of an emodepside 2.1% (w/v)/praziquantel 8.6% (w/v) topical solution (ProfenderR spot-on for cats) in the prevention of lactogenic Toxocara cati infections. A controlled test was performed with two groups of 8 cats with confirmed pregnancy. All cats were...

Author(s)
Böhm, C.; Petry, G.; Schaper, R.; Wolken, S.; Strube, C.
Publisher
Springer Berlin, Heidelberg, Germany
Citation
Parasitology Research, 2015, 114, Suppl. 1, pp 175-184

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