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Abstract

Case summary: An 11-year-old spayed female domestic shorthair cat with a history of hyperthyroidism treated with carbimazole for 7 months was presented for a check-up after a few episodes of vomiting. The cat had been receiving prednisolone at 0.5 mg/kg PO q12h for recent pancreatitis and...

Author(s)
Mosca, A.; Bresciani, L.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Journal of Feline Medicine and Surgery Open Reports, 2016, 2, 2, pp 4-2055116916668198
Abstract

AIM: To determine the pharmacokinetics of a novel lipophilic formulation of transdermal methimazole compared to oral carbimazole. METHODS: Healthy cats received 5 mg carbimazole orally every 12 hours for 13 treatments (n=6), then received transdermal methimazole (n=5) at a dose of 5 mg, then 10 mg, ...

Author(s)
Hill, K. E.; Gieseg, M. A.; Bridges, J.; Chambers, J. P.
Publisher
Taylor & Francis, Melbourne, Australia
Citation
New Zealand Veterinary Journal, 2014, 62, 4, pp 208-213
Abstract

Methimazole (thiamazole) is an antithyroid drug commonly used to treat feline hyperthyroidism. It is routinely given twice daily. Carbimazole is a methimazole derivative that is rapidly metabolized to methimazole in vivo. A controlled-release tablet for once-daily carbimazole therapy has recently...

Author(s)
Longhofer, S. L.; Martín-Jiménez, T.; Soni-Gupta, J.
Publisher
Veterinary Learning Systems, Yardley, USA
Citation
Veterinary Therapeutics, 2010, 11, 3, pp unpaginated
Abstract

An 11-year-old male neutered domestic shorthair cat presented with acute onset signs of generalised weakness and neck ventroflexion. He had been diagnosed with hyperthyroidism twomonths previously and been treated with daily carbimazole. No haematological, biochemical or electrolyte abnormalities...

Author(s)
Ellis, J.; Tappin, S.
Publisher
BMJ Publishing Group, London, UK
Citation
Veterinary Record Case Reports, 2019, 7, 1, pp e000806
Abstract

Feline hyperthyroidism can be treated medically, surgically or with radioactive iodine. Carbimazole inhibits both triiodothyronine and thyroxine synthesis in the thyroid gland and reported side effects include mild eosinophilia, leucopenia and lymphocytosis, thrombocytopenia, elevated liver enzyme...

Author(s)
Bowlt, K.; Cattin, I.; Stewart, J.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Small Animal Practice, 2014, 55, 12, pp 643-647
Abstract

Feline hyperthyroidism is a common condition in general practice and usually straightforward to diagnose. However, management can be challenging due to variable responses, owner preferences, side effects and comorbidities - necessitating an individualised approach to each case and careful...

Author(s)
Warland, J.
Publisher
Veterinary Business Development Ltd, Peterborough, UK
Citation
Veterinary Times, 2018, 48, 35, pp 14-15
Abstract

Orally administered antithyroid drugs are frequently used to treat hyperthyroidism in cats; however, the non-cooperative behaviour of some cats may make it difficult to administer tablets. The aim of this study was to develop a carbimazole ointment for application to the inner pinna of the ear and...

Author(s)
Buijtels, J. J. C. W. M.; Kurvers, I. A. P. G.; Galac, S.; Winter, E. A.; Kooistra, H. S.
Publisher
Koninklijke Nederlandse Maatschappij voor Diergeneeskunde, Utrecht, Netherlands
Citation
Tijdschrift voor Diergeneeskunde, 2006, 131, 13, pp 478-482
Abstract

Carbimazole, a prodrug of methimazole, is used in the treatment of hyperthyroidism in cats. The pharmacokinetics of methimazole was investigated in healthy cats following oral administration of 15 mg of carbimazole as a controlled-release tablet (Vidalta®, Intervet). The controlled-release tablet...

Author(s)
Frénais, R.; Burgaud, S.; Horspool, L. J. I.
Publisher
Blackwell Publishing, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2008, 31, 3, pp 213-219
Abstract

Background: Acquired myasthenia gravis (AMG) is increasingly recognized in cats, yet information regarding the natural history of the disease, treatment, and outcome including occurrence of immune and spontaneous remission remains limited. Objective: To determine the long-term outcome of cats with...

Author(s)
Mignan, T.; Garosi, L.; Targett, M.; Lowrie, M.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2020, 34, 1, pp 247-252
Abstract

Pharmacological management of feline hyperthyroidism offers a practical treatment option for many hyperthyroid cats. Two drugs have been licensed for cats in the last decade: methimazole and its pro-drug carbimazole. On the basis of current evidence and available tablet sizes, starting doses of 2.5 ...

Author(s)
Daminet, S.; Kooistra, H. S.; Fracassi, F.; Graham, P. A.; Hibbert, A.; Lloret, A.; Mooney, C. T.; Neiger, R.; Rosenberg, D.; Syme, H. M.; Villard, I.; Williams, G.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Small Animal Practice, 2014, 55, 1, pp 4-13

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