The diagnosis of liver and pancreatic disorders in dogs and cats present their own set of challenges. However, as new diagnostic tests are developed and the optimal ways in which to use existing tests are determined, the ability of the veterinary profession to make these diagnoses continues to...

Anorexia is one of the most common presenting signs in sick cats and is important to address since it has a number of potential adverse consequences including reduced immune function, altered drug metabolism and increased susceptibility to potentially fatal hepatic lipidosis. Nutritional assessment ...

Aims: This study aimed at isolating a probiotic strain from a collection of lactic acid bacteria (LAB) with the high antioxidant property and confirms its potential in D-gal-induced oxidative stress (OS) murine model. Methods and results: The in vitro antioxidant ability of 16 LAB strains was...

Laboratory evaluation of the hepatobiliary system has an important role in the diagnosis, monitoring, and assessment of patients with hepatobiliary diseases. Serum liver enzyme activities can be divided into markers of hepatocellular injury and cholestasis. Liver function can be assessed in several ...

Feline lymphocytic-plasmacytic gingivitis/stomatitis (LPGS) or caudal stomatitis is an inflammatory disease that causes painfully erosive lesions and proliferations of the oral mucosa. The disease is difficult to cure and can affect cats at an early age, resulting in lifetime therapy. In this...

Background - Severe Acute Liver Failure (ALF) is a life-threatening clinical syndrome characterized by hepatocyte necrosis, loss of hepatic architecture, and impairment of liver functions. One of the main causes of ALF is hepatotoxicity from chemical agents, which damage hepatocytes and result in...

Small-leaved Kuding tea is a traditional Chinese tea that is rich in polyphenols. In the current study, we investigated the preventive effect of small-leaved Kuding tea (SLKDT) on D-galactose-induced oxidative aging in mice. Changes in serum, skin, liver, and spleen of experimental animals were...

Determining the size of the heart is important for evaluating cardiac patients, because the increase of the cardiac silhouette in the chest radiography can be indicative of heart disease. The vertebral heart size (VHS) method is useful because it allows objective assessment of the limits of cardiac ...

Liver disease is relatively common in companion animal practice. Clinical signs can be vague and include weight loss, lethargy and anorexia, or be more specific, with signs of hepatic dysfunction such as jaundice or hepatic encephalopathy. Liver enzyme elevations can help guide the potential...

Clinical application of cyclophosphamide (CP) as an anticancer drug is often limited due to its toxicity. CP is metabolized mainly in the liver by cytochrome P450 system into acrolein which is the proximate toxic metabolite. Many different natural antioxidants were found to alleviate the toxic...