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VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

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Abstract

A 14-year-old, spayed female Domestic Shorthair cat was referred to the Purdue University Veterinary Teaching Hospital (PUVTH) for iodine 131 treatment of hyperthyroidism. Upon arrival, a biochemistry profile and a CBC were performed. Approximately 50% of the neutrophils and all the eosinophils...

Author(s)
Deshuillers, P.; Raskin, R.; Messick, J.
Publisher
Wiley-Blackwell, Boston, USA
Citation
Veterinary Clinical Pathology, 2014, 43, 3, pp 337-341
Abstract

A 9-year-old, castrated male Norwegian Forest cat was presented for a health examination. The initial complete blood cell count (CBC) revealed a degenerative left shift. The blood smear examination indicated significant nuclear hyposegmentation of the neutrophils, eosinophils, basophils, and...

Author(s)
Sakai, H.; Ano, H.; Kuze, N.; Sakai, K.
Publisher
Japanese Society of Clinical Veterinary Medicine, Tottori, Japan
Citation
Journal of Animal Clinical Medicine, 2017, 26, 4, pp 182-185
Abstract

Pelger-Huët anomaly is a rare hereditary disorder characterized by failure of the nucleus of granulocytes, especially neutrophils, to undergo normal maturation to the segmented form. Affected neutrophils have unsegmented or round nuclei, but chromatin condensation and cytoplasmic development...

Author(s)
Faria, R. D.; Zanella, A. C.; Tavares, B. C.; Bretas, G. F.; Santos, M. R. de D.; Monteiro, B. S.
Publisher
Universidade Federal do Paraná, UFPR, Curitiba, Brazil
Citation
Archives of Veterinary Science, 2012, 17, 4, pp 10-16
Abstract

Pelger Huet anomaly (PHA) is a hereditary disease characterized by non-segmentation of the granulocyte nuclei, especially neutrophils, due to a genetic defect in the lamin B-receptor (LBR) in chromosome 1q41-43. In that disorder, neutrophils present bilobulated, oval or round nuclei, and abundant...

Author(s)
Seki, M. C.; Anai, L. A.; Rosato, P. N.; Santana, A. E.
Publisher
Revista Unopar Cientifica, Londrina, Brazil
Citation
UNOPAR Científica Ciências Biológicas e da Saúde, 2011, 13, Special, pp 343-347
Abstract

Author(s)
Kridel, H. A.
Publisher
Educational Concepts LLC, Tulsa, USA
Citation
NAVC Clinician's Brief, 2016, No.October, pp 87-91
Abstract

Pelger-Huët anomaly was diagnosed in a young male cat on the basis of persistent nuclear hyposegmentation of blood granulocytes, absence of clinical disease or feline leukaemia virus infection, and demonstration of genetic transmission of the anomaly. Neutrophils, eosinophils, basophils, and...

Author(s)
Latimer, K. S.; Rakich, P. M.; Thompson, D. F.
Citation
Veterinary Pathology, 1985, 22, 4, pp 370-374
Abstract

Classification, clinical signs and diagnosis of immune dificiencies are described. Hereditary or congenital immunodificiences are classified as primary and are associated with recurrent infections and serious infections in new born animals which may result in death. Secondary or acquired...

Author(s)
Guerrero, F. F.
Publisher
ASIS Veterinaria s.l., Zaragoza, Spain
Citation
Argos - Informativo Veterinario, 2008, No.104, pp 52-, 54
Abstract

Leukogram, an important part of complete blood count, includes the total count, absolute differential counts and leukocyte morphology. For a valid interpretation of the leukogram, proper blood sampling and post-sampling handling is considered as prerequisite. Total leukocyte counts in the...

Author(s)
Petanides, T. A.; Mylonakis, M. E.; Koutinas, A. F.
Publisher
Hellenic Veterinary Medical Society, Athens, Greece
Citation
Deltion tes Ellenikes Kteniatrikes Etaireias = Journal of the Hellenic Veterinary Medical Society, 2004, 55, 2, pp 130-135
Abstract

A brother-sister mating of cats heterozygous for the Pelger-Huët anomaly produced 3 stillborn and 2 live kittens. One stillborn kitten was small with a domed skull, flat face and protruding tongue. All its limbs were short and thick with severe medial deviation. Radiography showed axial and...

Author(s)
Latimer, K. S.; Rowland, G. N.; Mahaffey, M. B.
Citation
Veterinary Pathology, 1988, 25, 4, pp 325-328
Abstract

The following primary immunodeficiencies are described: canine cyclic haematopoiesis (Collies), canine granulocytopathy syndrome (Irish Setters), neutrophil bacteriocidal defect (Dobermann Pinschers), Pelger-Huët anomaly (Domestic Shorthair cat and various canine breeds), Chédiak-Higashi syndrome...

Author(s)
Guilford, W. G.
Citation
Compendium on Continuing Education for the Practicing Veterinarian, 1987, 9, 6, pp 641-648, 650

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