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Abstract

Objectives: The amino acid substitutions M1058 L and S1060A in the spike protein of feline coronavirus (FCoV) have been postulated to be responsible for the development of the pathogenic feline infectious peritonitis virus (FIPV), which causes feline infectious peritonitis (FIP). The aim of the...

Author(s)
Sangl, L.; Matiasek, K.; Felten, S.; Gründl, S.; Bergmann, M.; Balzer, H. J.; Pantchev, N.; Leutenegger, C. M.; Hartmann, K.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Journal of Feline Medicine and Surgery, 2019, 21, 2, pp 133-142
Abstract

Feline infectious peritonitis (FIP) is a highly fatal disease caused by a virulent feline coronavirus in domestic and wild cats. We have previously reported the synthesis of potent coronavirus 3C-like protease (3CLpro) inhibitors and the efficacy of a protease inhibitor, GC376, in client-owned cats ...

Author(s)
Perera, K. D.; Rathnayake, A. D.; Liu HongWei; Pedersen, N. C.; Groutas, W. C.; Chang KyeongOk; Kim YunJeong
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Microbiology, 2019, 237, pp 108398
Abstract

Background: There are two biotypes of feline coronavirus (FCoV): the self-limiting feline enteric coronavirus (FECV) and the feline infectious peritonitis virus (FIPV), which causes feline infectious peritonitis (FIP), a fatal disease associated with cats living in multi-cat environments. This...

Author(s)
Nikoo Safi; Amin Haghani; Ng ShingWei; Gayathri Thevi Selvarajah; Farina Mustaffa-Kamal; Abdul Rahman Omar
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2017, 13, 92, pp (7 April 2017)
Abstract

Feline infectious peritonitis virus (FIPV) causes a severe, immune-mediated disease called FIP in domestic and wild cats. It is unclear whether FIP transmits from cat to cat through the oral route of FIPV infection, and the reason for this includes that FIP is caused by oral inoculation with some...

Author(s)
Takano, T.; Yamada, S.; Doki, T.; Hohdatsu, T.
Publisher
Japanese Society of Veterinary Science, Tokyo, Japan
Citation
Journal of Veterinary Medical Science, 2019, 81, 6, pp 911-915
Abstract

Background: Feline coronavirus (FCoV) exists as two pathotypes, and FCoV spike gene mutations are considered responsible for the pathotypic switch in feline infectious peritonitis (FIP) pathogenesis. The aim of this study was to evaluate sensitivity and specificity of a real-time reverse...

Author(s)
Felten, S.; Leutenegger, C. M.; Balzer, H. J.; Pantchev, N.; Matiasek, K.; Wess, G.; Egberink, H.; Hartmann, K.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2017, 13, 228, pp (2 August 2017)
Abstract

Background: Feline infectious peritonitis (FIP) is considered highly fatal in its naturally occurring form, although up to 36% of cats resist disease after experimental infection, suggesting that cats in nature may also resist development of FIP in the face of infection with FIP virus (FIPV)....

Author(s)
Mustaffa-Kamal, F.; Liu HongWei; Pedersen, N. C.; Sparger, E. E.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2019, 15, 165, pp (22 May 2019)
AbstractFull Text

Feline Infectious Peritonitis (FIP) and Feline Panleukopenia Virus (FPV) are both of the most significant viral agents which affect negatively to the domestic cats' health. In this regards, we aimed to elucidate the prevalence status of FIP and FPV in domestic cats. With this aim, mentioned...

Author(s)
Koç, B. T.; Akkutay-Yoldar, Z.; Ülgenalp, O.; Oğuzoğlu, T. Ç.
Publisher
Organising Committee, ICABB 2018, Aksaray, Turkey
Citation
2nd International Congress on Advances in Bioscience and Biotechnology (ICABB), Podgorica, Montenegro, 26-30 June 2018. Book of Proceedings, 2018, pp 36-38
Abstract

Objectives: Feline coronaviruses (FCoVs) exist as two biotypes, feline enteric coronavirus and feline infectious peritonitis virus. Although feline infectious peritonitis (FIP) is a very common disease, the ante-mortem diagnosis of this disease still remains a challenge. Immunofluorescence staining ...

Author(s)
Felten, S.; Matiasek, K.; Gruendl, S.; Sangl, L.; Wess, G.; Hartmann, K.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Journal of Feline Medicine and Surgery, 2017, 19, 4, pp 410-418
Abstract

Feline coronavirus (FCoV) is classified into two biotypes based on its pathogenicity in cats: a feline enteric coronavirus of low pathogenicity and a highly virulent feline infectious peritonitis virus. It has been suspected that FCoV alters its biotype via mutations in the viral genome. The S and ...

Author(s)
Oguma, K.; Ohno, M.; Yoshida, M.; Sentsui, H.
Publisher
Japanese Society of Veterinary Science, Tokyo, Japan
Citation
Journal of Veterinary Medical Science, 2018, 80, 7, pp 1094-1100
Abstract

The present study describes the association between inflammatory cell types and feline infectious peritonitis virus (FIPV) antigen in the brain of 4 cats diagnosed as feline infectious peritonitis (FIP). Immunohistochemically, FIPV antigens were detected in the inflammatory foci of the...

Author(s)
Wang HuaNan; Hirabayashi, M.; Chambers, J. K.; Uchida, K.; Nakayama, H.
Publisher
Japanese Society of Veterinary Science, Tokyo, Japan
Citation
Journal of Veterinary Medical Science, 2018, 80, 12, pp 1813-1817

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