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Abstract

Objectives: The amino acid substitutions M1058 L and S1060A in the spike protein of feline coronavirus (FCoV) have been postulated to be responsible for the development of the pathogenic feline infectious peritonitis virus (FIPV), which causes feline infectious peritonitis (FIP). The aim of the...

Author(s)
Sangl, L.; Matiasek, K.; Felten, S.; Gründl, S.; Bergmann, M.; Balzer, H. J.; Pantchev, N.; Leutenegger, C. M.; Hartmann, K.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Journal of Feline Medicine and Surgery, 2019, 21, 2, pp 133-142
Abstract

Feline infectious peritonitis (FIP) is a highly fatal disease caused by a virulent feline coronavirus in domestic and wild cats. We have previously reported the synthesis of potent coronavirus 3C-like protease (3CLpro) inhibitors and the efficacy of a protease inhibitor, GC376, in client-owned cats ...

Author(s)
Perera, K. D.; Rathnayake, A. D.; Liu HongWei; Pedersen, N. C.; Groutas, W. C.; Chang KyeongOk; Kim YunJeong
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Microbiology, 2019, 237, pp 108398
Abstract

Feline infectious peritonitis virus (FIPV) causes a severe, immune-mediated disease called FIP in domestic and wild cats. It is unclear whether FIP transmits from cat to cat through the oral route of FIPV infection, and the reason for this includes that FIP is caused by oral inoculation with some...

Author(s)
Takano, T.; Yamada, S.; Doki, T.; Hohdatsu, T.
Publisher
Japanese Society of Veterinary Science, Tokyo, Japan
Citation
Journal of Veterinary Medical Science, 2019, 81, 6, pp 911-915
Abstract

Background: There are two biotypes of feline coronavirus (FCoV): the self-limiting feline enteric coronavirus (FECV) and the feline infectious peritonitis virus (FIPV), which causes feline infectious peritonitis (FIP), a fatal disease associated with cats living in multi-cat environments. This...

Author(s)
Nikoo Safi; Amin Haghani; Ng ShingWei; Gayathri Thevi Selvarajah; Farina Mustaffa-Kamal; Abdul Rahman Omar
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2017, 13, 92, pp (7 April 2017)
Abstract

Background: Feline coronavirus (FCoV) exists as two pathotypes, and FCoV spike gene mutations are considered responsible for the pathotypic switch in feline infectious peritonitis (FIP) pathogenesis. The aim of this study was to evaluate sensitivity and specificity of a real-time reverse...

Author(s)
Felten, S.; Leutenegger, C. M.; Balzer, H. J.; Pantchev, N.; Matiasek, K.; Wess, G.; Egberink, H.; Hartmann, K.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2017, 13, 228, pp (2 August 2017)
Abstract

Feline coronavirus (FCoV) is classified into two biotypes based on its pathogenicity in cats: a feline enteric coronavirus of low pathogenicity and a highly virulent feline infectious peritonitis virus. It has been suspected that FCoV alters its biotype via mutations in the viral genome. The S and ...

Author(s)
Oguma, K.; Ohno, M.; Yoshida, M.; Sentsui, H.
Publisher
Japanese Society of Veterinary Science, Tokyo, Japan
Citation
Journal of Veterinary Medical Science, 2018, 80, 7, pp 1094-1100
Abstract

Feline infectious peritonitis (FIP) is one of the most important infectious diseases in cats and is caused by feline coronavirus (FCoV). Tissue culture-adapted type I FCoV shows reduced FIP induction in experimental infections, which complicates the understanding of FIP pathogenesis caused by type...

Author(s)
Terada, Y.; Kuroda, Y.; Morikawa, S.; Matsuura, Y.; Maeda, K.; Kamitani, W.
Publisher
American Society for Microbiology (ASM), Washington, D.C., USA
Citation
Journal of Virology, 2019, 93, 21, pp e01208-19
Abstract

Feline infectious peritonitis (PIF) is a progressive and fatal disease for domestic and wild cats caused by Feline coronavirus (CoVF) and occurs in two forms: effusive (wet) or non-effusive (dry). The effusive PIF develops when the cell-mediated response is minimal, effusion is detected by...

Author(s)
Rodrigues, H. A. S.; Cabral, A. E. P.; Silva, M. C. B.; Muniz, I. M.
Publisher
Faculdade de Ciências Agrárias e Veterinárias, Câmpus de Jaboticabal, UNESP, Jaboticabal, Brazil
Citation
Ars Veterinaria, 2018, 34, 4 Suplemento, pp 186-187
Abstract

The aim of the study was to identify peptides within the polyprotein (Pp) 1 ab that are differentially recognised by cats with either enteric or systemic disease following infection with feline coronavirus. Overlapping 12-mer peptides (n=28,426) across the entire Pp1ab were arrayed on peptide chips ...

Author(s)
Chernyavtseva, A.; Cave, N. J.; Munday, J. S.; Dunowska, M.
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Virology, 2019, 532, pp 88-96
Abstract

Case summary: This report describes a cat with chronic, progressive, non-painful, non-lateralizing multifocal neurologic clinical signs associated with feline infectious peritonitis (FIP). The cat initially presented as underweight, despite a good appetite, and a complete blood count showed...

Author(s)
André, N. M.; Cossic, B.; Davies, E.; Miller, A. D.; Whittaker, G. R.
Publisher
Sage Publications Ltd, London, UK
Citation
Journal of Feline Medicine and Surgery Open Reports, 2019, 5, 1, pp 31-2055116919856103

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