Cookies on VetMed Resource

Like most websites we use cookies. This is to ensure that we give you the best experience possible.

 

Continuing to use www.cabi.org  means you agree to our use of cookies. If you would like to, you can learn more about the cookies we use.

VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

Sign up to receive our Veterinary & Animal Sciences e-newsletter, book alerts and offers direct to your inbox.

Results per page:

Search results

Abstract

Radioiodine is considered the treatment of choice for hyperthyroidism, but in some situations, methimazole therapy is preferred, such as in cats with preexisting renal insufficiency. Unfavorable outcomes from methimazole are usually attributable to side effects, such as gastrointestinal upset,...

Author(s)
Trepanier, L. A.
Publisher
W.B. Saunders, Philadelphia, USA
Citation
Veterinary Clinics of North America, Small Animal Practice, 2007, 37, 4, pp 775-788
Abstract

Background: Reversible antioxidant depletion is found in hyperthyroid humans, and antioxidant depletion increases the risk of methimazole toxicosis in rats. Objectives: To determine whether abnormalities in concentrations of blood antioxidants or urinary isoprostanes were present in hyperthyroid ...

Author(s)
Branter, E.; Drescher, N.; Padilla, M.; Trepanier, L. A.
Publisher
Wiley-Blackwell, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2012, 26, 3, pp 582-588
Abstract

Radioiodine is considered the treatment of choice for hyperthyroidism, but in some situations, methimazole therapy is preferred, such as in cats with pre-existing renal insufficiency. Methimazole blocks thyroid hormone synthesis, and controls hyperthyroidism in more than 90% of cats that tolerate...

Author(s)
Trepanier, L. A.
Publisher
Elsevier Inc, Orlando, USA
Citation
Clinical Techniques in Small Animal Practice, 2006, 21, 1, pp 22-28
Abstract

Objective - To determine whether once daily administration of methimazole was as effective and safe as twice daily administration in cats with hyperthyroidism. Design - Randomized, nonblinded, clinical trial. Animals - 40 cats with newly diagnosed hyperthyroidism. Procedure - Cats were randomly...

Author(s)
Trepanier, L. A.; Hoffman, S. B.; Kroll, M.; Rodan, I.; Challoner, L.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
Journal of the American Veterinary Medical Association, 2003, 222, 7, pp 954-963
Abstract

The objective of this study was to determine whether transdermal methimazole was as safe and effective as oral methimazole for the control of hyperthyroidism in cats. Forty-seven cats with newly diagnosed hyperthyroidism were randomized to receive either transdermal methimazole in pluronic lecithin ...

Author(s)
Sartor, L. L.; Trepanier, L. A.; Kroll, M. M.; Rodan, I.; Challoner, L.
Publisher
American College of Veterinary Internal Medicine, Lakewood, USA
Citation
Journal of Veterinary Internal Medicine, 2004, 18, 5, pp 651-655
Abstract

The antithyroid drug methimazole is widely used for the medical management of feline hyperthyroidism. Recently, custom veterinary pharmacies have offered methimazole in a transdermal gel containing pluronic and lecithin (PLO), with anecdotal evidence of efficacy. The purpose of this study was to...

Author(s)
Hoffman, S. B.; Yoder, A. R.; Trepanier, L. A.
Publisher
Blackwell Science, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2002, 25, 3, pp 189-193
Abstract

The intravenous and oral disposition of the anti-thyroid drug methimazole was determined in 10 healthy cats and nine cats with naturally occurring hyperthyroidism. After intravenous administration of 5 mg methimazole, the mean residence time was significantly shorter in the cats with ...

Author(s)
Trepanier, L. A.; Peterson, M. E.; Aucoin, D. P.
Citation
Research in Veterinary Science, 1991, 50, 1, pp 69-74
Abstract

Author(s)
Trepanier, L. A.
Citation
Problems in Veterinary Medicine, 1990, 2, 4, pp 668-682

Refine Results

Sort Order
Author
Geographical Location
Organisms
Subject Topics