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Abstract

Since the first description of feline hyperthyroidism (HT) in 1979, several studies have been undertaken to define the etiology of the disease. Epidemiologic studies, after investigating non-food- and food-associated factors, suggest a multifactorial etiology. However, in the absence of prospective ...

Author(s)
Hoek, I. van; Hesta, M.; Biourge, V.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Journal of Feline Medicine and Surgery, 2015, 17, 10, pp 837-847
Abstract

Thyroid gland palpation is an important aid for diagnosing feline hyperthyroidism in an early stage to prevent development of deleterious complications. Our objectives were to assess within- and between-examiner agreement for two thyroid gland palpation techniques in cats and to correlate palpation ...

Author(s)
Paepe, D.; Smets, P.; Hoek, I. van; Saunders, J.; Duchateau, L.; Daminet, S.
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Journal of Feline Medicine and Surgery, 2008, 10, 6, pp 558-565
Abstract

Recombinant human thyrotropin (rhTSH) was developed after bovine thyrotropin (bTSH) was no longer commercially available. It was approved by the Food and Drug Administration (FDA) and the European Medicines Agency (EMEA) as an aid to diagnostic follow-up of differentiated thyroid carcinoma in...

Author(s)
Campos, M.; Hoek, I. van; Peremans, K.; Daminet, S.
Publisher
Wiley-Blackwell, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2012, 26, 4, pp 853-862
Abstract

Feline hyperthyroidism is currently the most diagnosed endocrine disorder in cats. It is caused by benign adenomatous hyperplasia of the thyroid gland in 98% of the cases. The two major non-surgical treatment options, administration of antithyroid drugs and radioiodine therapy, are reviewed in this ...

Author(s)
Hoek, I. van; Peremans, K.; Waelbers, T.; Vandermeulen, E.; Daminet, S.
Publisher
Faculty of Veterinary Medicine, University of Ghent, Merelbeke, Belgium
Citation
Vlaams Diergeneeskundig Tijdschrift, 2007, 76, 2, pp 69-80
Abstract

The presence of low molecular weight retinol binding protein (RBP) in urine reflects tubular damage. Therefore, RBP has been used as a renal marker in humans and dogs. Using an anti-human RBP antibody (Ab), this study first demonstrates feline urinary RBP by Western blot analysis and then evaluates ...

Author(s)
Hoek, I. van; Daminet, S.; Notebaert, S.; Janssens, I.; Meyer, E.
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Journal of Immunological Methods, 2008, 329, 1/2, pp 208-213
Abstract

Absorbed thyroid dose and effective half-life were determined in 46 hyperthyroid cats after treatment with a low dose (mean 111 MBq) of radioiodine intravenously. Thirteen of these cats had received iohexol for glomerular filtration rate (GFR) measurement within 24 h before treatment with...

Author(s)
Peremans, K.; Vandermeulen, E.; Hoek, I. van; Daminet, S.; Vermeire, S.; Bacher, K.
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Journal of Feline Medicine and Surgery, 2008, 10, 5, pp 460-465
Abstract

Ultrasonography is useful for assessing the morphology of the thyroid gland in hyperthyroid cats. Our aim was to describe the ultrasonographic changes of the thyroid gland in hyperthyroid cats after 131I therapy. Ultrasonography was performed in 15 hyperthyroid cats at initial presentation and 6...

Author(s)
Barberet, V.; Baeumlin, Y.; Taeymans, O.; Duchateau, L.; Peremans, K.; Hoek, I. van; Daminet, S.; Saunders, J. H.
Publisher
Blackwell Publishing, Boston, USA
Citation
Veterinary Radiology & Ultrasound, 2010, 51, 3, pp 324-330
Abstract

Background: Chronic kidney failure is frequently seen in middle-aged and elderly cats. 51Chromium-ethylene diaminic tetraacetic acid (51Cr-EDTA) clearance and single blood sample (SBS) method are used in several species to estimate the glomerular filtration rate (GFR). Hypothesis: The hypothesis of ...

Author(s)
Vandermeulen, E.; Hoek, I. van; Sadeleer, C. de; Piepsz, A.; Ham, H. R.; Bosmans, T.; Dobbeleir, A.; Daminet, S.; Peremans, K.
Publisher
Blackwell Publishing, Oxford, UK
Citation
Journal of Veterinary Internal Medicine, 2008, 22, 2, pp 266-272
Abstract

Hyperthyroidism can mask co-existing chronic kidney disease (CKD). Previous studies showed that post-treatment renal azotemia can be predicted by pre-treatment assessment of glomerular filtration rate (GFR). We hypothesized that treatment of hyperthyroidism may have different effects on glomerular...

Author(s)
Hoek, I. van; Lefebvre, H. P.; Peremans, K.; Meyer, E.; Croubels, S.; Vandermeulen, E.; Kooistra, H.; Saunders, J. H.; Binst, D.; Daminet, S.
Publisher
Elsevier, New York, USA
Citation
Domestic Animal Endocrinology, 2009, 36, 1, pp 45-56
Abstract

Background: Hyperthyroidism is the most diagnosed endocrine disorder in cats and radioiodine (131I) is the treatment of choice. The dose emission rate and radioactivity in urine, saliva, and on hair and paws are determined by the dose of administered 131I. A dose reduction of therapeutic 131I could ...

Author(s)
Hoek, I. van; Daminet, S.; Vandermeulen, E.; Dobbeleir, A.; Duchateau, L.; Peremans, K.
Publisher
Blackwell Publishing, Oxford, UK
Citation
Journal of Veterinary Internal Medicine, 2008, 22, 6, pp 1340-1344

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