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Abstract

The Burmese is a breed of domestic cat that originated in Southeast Asia and was further developed in the United States. Variants in melanocortin 1 receptor (MC1R) causes common coat colour phenotypes in a variety of mammalian species but only limited colour variation in the domestic cat. Known as...

Author(s)
Gustafson, N. A.; Gandolfi, B.; Lyons, L. A.
Publisher
Wiley, Oxford, UK
Citation
Animal Genetics, 2017, 48, 1, pp 116-120
Abstract

A novel coloration named 'mocha' has been identified in the Burmese cat breed from Thailand. Tyrosinase (TYR) mutations are known to be associated with coat coloration in cats, such as the sable Burmese, the points of the Siamese and albino cats. Additionally, sable Burmese that produced...

Author(s)
Yu, Y.; Grahn, R. A.; Lyons, L. A.
Publisher
Wiley, Oxford, UK
Citation
Animal Genetics, 2019, 50, 2, pp 182-186
Abstract

Frontonasal dysplasia (FND) can have severe presentations that are medically and socially debilitating. Several genes are implicated in FND conditions, including Aristaless-Like Homeobox 1 (ALX1), which is associated with FND3. Breeds of cats are selected and bred for extremes in craniofacial...

Author(s)
Lyons, L. A.; Erdman, C. A.; Grahn, R. A.; Hamilton, M. J.; Carter, M. J.; Helps, C. R.; Alhaddad, H.; Gandolfi, B.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Developmental Biology, 2016, 409, 2, pp 451-458
Abstract

Global importance: Hypokalaemic polymyopathy is a genetic disease of Burmese cats that has been encountered in Australasia, Europe and South Africa. Clinical features: Affected cats usually present with signs of muscle weakness and muscle pain in the first year of life. Although certain clinical...

Author(s)
Malik, R.; Musca, F. J.; Gunew, M. N.; Menrath, V. H.; Simpson, C.; Culvenor, J.; Grahn, R. A.; Helps, C.; Lyons, L. A.; Gandolfi, B.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Journal of Feline Medicine and Surgery, 2015, 17, 5, pp 417-426
Abstract

The Siamese cat has a highly recognized coat colour phenotype that expresses pigment at the extremities of the body, such as the ears, tail and paws. This temperature-sensitive colouration causes a 'mask' on the face and the phenotype is commonly referred to as 'pointed'. Burmese is an allelic...

Author(s)
Lyons, L. A.; Imes, D. L.; Rah, H. C.; Grahn, R. A.
Publisher
Blackwell Publishing, Oxford, UK
Citation
Animal Genetics, 2005, 36, 2, pp 119-126
Abstract

Domestic cats have a unique breeding history and can be used as models for human hereditary and infectious diseases. In the current era of genome-wide association studies, insights regarding linkage disequilibrium (LD) are essential for efficient association studies. The objective of this study is...

Author(s)
Alhaddad, H.; Khan, R.; Grahn, R. A.; Gandolfi, B.; Mullikin, J. C.; Cole, S. A.; Gruffydd-Jones, T. J.; Häggström, J.; Lohi, H.; Longeri, M.; Lyons, L. A.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2013, 8, 1, pp e53537
Abstract

Albino phenotypes are documented in a variety of species including the domestic cat. As albino phenotypes in other species are associated with tyrosinase (TYR) mutations, TYR was proposed as a candidate gene for albinism in cats. An Oriental and Colourpoint Shorthair cat pedigree segregating for...

Author(s)
Imes, D. L.; Geary, L. A.; Grahn, R. A.; Lyons, L. A.
Publisher
Blackwell Publishing, Oxford, UK
Citation
Animal Genetics, 2006, 37, 2, pp 175-178

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