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Abstract

Objectives: To evaluate the serum symmetric dimethylarginine (SDMA) and serum creatinine concentrations in a population of hypothyroid dogs at the time of diagnosis and after treatment. Materials and Methods: Serum SDMA and serum creatinine were measured in serum samples of 24 healthy dogs and 24...

Author(s)
Paola, A. di; Carotenuto, G.; Dondi, F.; Corsini, A.; Corradini, S.; Fracassi, F.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2020, 62, 2, pp 89-96
Abstract

Background: Serum creatinine and symmetric dimethylarginine (SDMA) are used as surrogate markers of glomerular filtration rate (GFR) in clinical practice. Data pertaining to the correlations between GFR, SDMA, and serum creatinine in client-owned dogs are limited. Objectives: To describe the...

Author(s)
McKenna, M.; Pelligand, L.; Elliott, J.; Cotter, D.; Jepson, R.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2020, 34, 1, pp 186-194
Abstract

Symmetric dimethylarginine (SDMA) is considered an important biomarker of kidney dysfunction. The aims of the study were to evaluate SDMA in dogs with acute pancreatitis (AP) and its relationship with the presence of kidney injury and mortality. A cohort study including fifty-four dogs with AP...

Author(s)
Gori, E.; Pierini, A.; Lippi, I.; Meucci, V.; Perondi, F.; Marchetti, V.
Publisher
MDPI AG, Basel, Switzerland
Citation
Veterinary Sciences, 2020, 7, 2,
Abstract

Kidney disease is common in companion animals, and traditionally diagnosed with serum creatinine concentration (sCr), blood urea nitrogen, and abnormal urinalysis findings. Symmetric dimethylarginine (SDMA) is a novel kidney biomarker that reflects glomerular filtration rate, increasing earlier...

Author(s)
Ernst, R.; Ogeer, J.; McCrann, D.; Cross, J.; Strong-Townsend, M.; Friis, H.; Coyne, M.; Clements, C.; Drake, C.; Murphy, R.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2018, 13, 10, pp e0205030
Abstract

Objective: To evaluate symmetric dimethylarginine (SDMA) and serum creatinine (sCr) for detection of early chronic kidney disease (CKD) in a prospective, longitudinal study of older dogs. Sample Population Forty three healthy dogs with an initial median age of 8.9 years. Procedures SDMA, serum and...

Author(s)
Guess, S. C.; Yerramilli, M.; Obare, E. F.; Grauer, G. F.
Publisher
Veterinary Solutions LLC, Apopka, USA
Citation
International Journal of Applied Research in Veterinary Medicine, 2018, 16, 2, pp 122-130
Abstract

Symmetric dimethylarginine (SDMA) is a promising renal marker that correlates well with the glomerular filtration rate and could allow earlier detection of impaired renal function. The main objectives of this study were to assess the long-term variability of SDMA in healthy dogs and examine the...

Author(s)
Hillaert, A.; Liu, D. J. X.; Daminet, S.; Broeckx, B. J. G.; Stock, E.; Paepe, D.; Hesta, M.; Vanderperren, K.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2021, 16, 2,
Abstract

Background: Symmetric dimethylarginine (SDMA) is considered a biomarker for early detection of renal dysfunction in human patients with acute kidney injury (AKI). At present, no studies exist analyzing the relevance of SDMA in dogs with AKI. Hypothesis/objectives: SDMA would correctly identify dogs ...

Author(s)
Dahlem, D. P.; Neiger, R.; Schweighauser, A.; Francey, T.; Yerramilli, M.; Obare, E.; Steinbach, S. M. L.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2017, 31, 3, pp 799-804
Abstract

Symmetric dimethylarginine (SDMA) is a serum biomarker of renal damage in dogs. Moreover, SDMA concentration is an independent predictor of development of severe heart failure (HF) in humans with cardiac disease. This study evaluates whether the serum concentration of SDMA in dogs with myxomatous...

Author(s)
Valente, C.; Guglielmini, C.; Domenech, O.; Contiero, B.; Zini, E.; Poser, H.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2020, 15, 9,
Abstract

Background: Symmetric dimethylarginine (SDMA) reflects the glomerular filtration rate (GFR) in people, dogs, and cats. Initial assays used a liquid chromatography-mass spectroscopy (LC) technique. A veterinary immunoassay has been developed for use in commercial laboratories and point-of-care (POC) ...

Author(s)
Baral, R. M.; Freeman, K. P.; Flatland, B.
Publisher
Wiley, Boston, USA
Citation
Veterinary Clinical Pathology, 2021, 50, 1, pp 57-61
Abstract

Objective: To determine if there is an association between the concentration of symmetric dimethylarginine (SDMA) in dogs measured at the time of admission with the severity of critical illness and short-term mortality. Design: This prospective observational study recruited critically ill dogs with ...

Author(s)
Köster, L. S.; Peda, A.; Fraites, T.; Sithole, F.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Emergency and Critical Care, 2018, 28, 6, pp 527-531

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