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Abstract

Nonsteroidal anti-inflammatory drugs (NSAID) are commonly used in combination with antimicrobial mastitis treatments to reduce pain. Little is known about whether meloxicam, an NSAID designed for the preferential inhibition of cyclooxygenase-2 over cyclooxygenase-1, affects the mammary immune...

Author(s)
Caldeira, M. O.; Bruckmaier, R. M.; Wellnitz, O.
Publisher
Elsevier Inc., Philadelphia, USA
Citation
Journal of Dairy Science, 2021, 104, 1, pp 1039-1052
Abstract

Recently, it has been shown that the addition of meloxicam to standard antimicrobial therapy for clinical mastitis (CM) improves the conception rate of dairy cows contracting CM in the first 120 d in milk. The objective of our study was to assess whether this improved reproduction through...

Author(s)
Soest, F. J. S. van; Abbeloos, E.; McDougall, S.; Hogeveen, H.
Publisher
Elsevier Inc., Philadelphia, USA
Citation
Journal of Dairy Science, 2018, 101, 4, pp 3387-3397
Abstract

Objective: The post partum use of analgesics in cows has increased in consequence to society's increased awareness of animal welfare. However, it is known that the post partum administration of a subset of nonsteroidal anti-inflammatory drugs to cows may lead to an increased rate of retained...

Author(s)
Kunz, F.; Koca, D.; Failing, K.; Wehrend, A.; Sendag, S.
Publisher
Schattauer GmbH, Stuttgart, Germany
Citation
Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere, 2019, 47, 5, pp 281-284
Abstract

In the present field study the effectiveness of a treatment of mild and moderate acute catarrhal mastitis using a combination of locally administered Cefalexin and Kanamycin with and without concurrent intravenous application of Meloxicam was investigated. In total 81 cows with mastitis from dairy...

Author(s)
Gindhart, I.; Martin, R.; Sauter-Louis, C.; Mansfeld, R.
Publisher
Schlütersche Verlagsgesellschaft GmbH & Co. KG, Hannover, Germany
Citation
Praktische Tierarzt, 2016, 97, 12, pp 1104...1117
Abstract

Dairy cows with metritis display sickness behaviors, and nonsteroidal anti-inflammatory drugs (NSAID) have the potential to reduce these responses. The objective of this study was to investigate changes in feeding, social, and lying behaviors in dairy cows with metritis that had been treated with...

Author(s)
Lomb, J.; Neave, H. W.; Weary, D. M.; LeBlanc, S. J.; Huzzey, J. M.; Keyserlingk, M. A. G. von
Publisher
Elsevier Inc., Philadelphia, USA
Citation
Journal of Dairy Science, 2018, 101, 5, pp 4400-4411
Abstract

The objective of this study reported here was determine whether differences occurred in meloxicam pharmacokinetics between postpartum cows and mid-lactation cows. Preliminary data from a separate study (P. J. Gorden, unpublished data) in postpartum cows demonstrated elevated plasma and milk...

Author(s)
Gorden, P. J.; Burchard, M.; Ydstie, J. A.; Kleinhenz, M. D.; Wulf, L. W.; Rajewski, S. J.; Wang, C.; Gehring, R.; Mochel, J. P.; Coetzee, J. F.
Publisher
Wiley, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2018, 41, 3, pp 463-468
Abstract

Lactating dairy cattle are at risk for various painful conditions throughout their life, such as lameness, parturition, mastitis, and metabolic disorders. These conditions necessitate adequate methods of analgesia to address welfare concerns through efficacious pain mitigation. As no method of...

Author(s)
Warner, R.; Ydstie, S. A.; Wulf, L. W.; Gehring, R.; Coetzee, J. F.; Mochel, J. P.; Gorden, P. J.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2020, 6, September,
Abstract

During inflammation of the mammary gland, the blood-milk barrier, which is predominantly composed of mammary epithelial cells, loses its integrity and gradients between blood and milk cannot be maintained. Nonsteroidal anti-inflammatory drugs (NSAID) are commonly used systemically in combination...

Author(s)
Sintes, G. F.; Bruckmaier, R. M.; Wellnitz, O.
Publisher
Elsevier Inc., Philadelphia, USA
Citation
Journal of Dairy Science, 2020, 103, 11, pp 10742-10753
Abstract

Research investigating the pain of normal parturition is lacking as there are few objective methods for measuring pain. The objective of this research was to describe the gait of cows following eutocia using pressure mat gait analysis; and if meloxicam alters the gait of cows. Twenty Holstein cows...

Author(s)
Kleinhenz, M. D.; Gorden, P. J.; Burchard, M.; Ydstie, J. A.; Coetzee, J. F.
Publisher
Oxford University Press, Cary, USA
Citation
Journal of Animal Science, 2019, 97, 2, pp 846-850
Abstract

Abruptly weaned crossbred steer calves (N = 271) were used in a randomized, blinded 2-arm clinical trial to assess the impact of a long-acting non-steroidal anti-inflammatory drug on bovine herpesvirus type 1, bovine respiratory syncytial virus, parainfluenza virus type 3, and coronavirus titers...

Author(s)
Homerosky, E. R.; Jelinski, M. J.; Dorin, C.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Journal of Veterinary Research, 2021, 85, 2, pp 101-105

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