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Abstract

Background: The widespread use of individual sires for artificial insemination promotes the propagation of recessive conditions. Inadvertent matings between unnoticed carriers of deleterious alleles may result in the manifestation of fatal phenotypes in their progeny. Breeding consultants and...

Author(s)
Pausch, H.; Ammermüller, S.; Wurmser, C.; Hamann, H.; Tetens, J.; Drögemüller, C.; Fries, R.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genetics, 2016, 17, 149, pp (1 December 2016)
Abstract

Four newborn purebred Belgian Blue calves presenting a severe form of epidermolysis bullosa were recently referred to our heredo-surveillance platform. SNP array genotyping followed by autozygosity mapping located the causative gene in a 8.3-Mb interval on bovine chromosome 24. Combining...

Author(s)
Sartelet, A.; Harland, C.; Tamma, N.; Karim, L.; Bayrou, C.; Li WanBo; Ahariz, N.; Coppieters, W.; Georges, M.; Charlier, C.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Animal Genetics, 2015, 46, 5, pp 566-570
Abstract

We identified a congenital mechanobullous skin disorder in six calves on a single farm of an endangered German cattle breed in 2010. The condition presented as a large loss of skin distal to the fetlocks and at the mucosa of the muzzle. All affected calves were euthanized on humane grounds due to...

Author(s)
Menoud, A.; Welle, M.; Tetens, J.; Lichtner, P.; Drögemüller, C.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2012, 7, 6, pp e38823
Abstract

A case of epidermolysis bullosa in a calf descendent from a Gir bull and a Gir crossbreed cow is reported. The calf presented with exungulation of all hooves, widespread erosions and crusts on the skin, and ulcers in the oral cavity. Histologically, the skin showed subepidermal separation with...

Author(s)
Medeiros, G. X.; Riet-Correa, F.; Armién, A. G.; Dantas, A. F. M.; Galiza, G. J. N. de; Simões, S. V. D.
Publisher
American Association of Veterinary Laboratory Diagnosticians, Davis, USA
Citation
Journal of Veterinary Diagnostic Investigation, 2012, 24, 1, pp 231-234
Abstract

A total of 5 calves from a herd of 35 Simmental cross cows bred with a Simmental bull were diagnosed with epidermolysis bullosa in a farm in the UK in 1996, based on clinical and gross pathological features. Two more cases were presented the following year. The farmer was advised to change his...

Author(s)
Matthews, G.; Allen, M.
Publisher
British Veterinary Association, London, UK
Citation
Veterinary Record, 2005, 157, 15, pp 456
Abstract

Epidermolysis bullosa (EB) was diagnosed in eight calves from four farms in the United Kingdom on the basis of clinical, histological and ultrastructural findings. In three affected herds, pedigree Simmental bulls had been mated with Simmental-cross cows. In a fourth herd two Holstein-Friesian...

Author(s)
Foster, A. P.; Skuse, A. M.; Higgins, R. J.; Barrett, D. C.; Philbey, A. W.; Thomson, J. R.; Thompson, H.; Fraser, M. A.; Bowden, P. E.; Day, M. J.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Journal of Comparative Pathology, 2010, 142, 4, pp 336-340
Abstract

Twenty-five of 72 calves sired by a Simmental bull were affected with a congenital skin disease which appeared to be inherited as an autosomal dominant trait. The affected calves showed hypotrichosis, erythema and breaks in the integrity of the skin. The distribution of the lesions and the ease...

Author(s)
Bassett, H.
Citation
Veterinary Record, 1987, 121, 1, pp 8-11
Abstract

Bovine epidermolysis, a recently identified skin disease seen in the descendants of a Simmental bull, was reproduced experimentally. Twenty two calves were born when affected males were mated with normal females; bovine epidermolysis was confirmed in four male and six female calves. Six calves were ...

Author(s)
Bassett, H.
Citation
Proceedings of the 14th World Congress on Diseases of Cattle, Dublin, 1986, 1, pp 75-80
Abstract

Recently, α6 integrin has been proposed as the epithelial cell receptor for papillomavirus. The role of α6 integrin as the cellular receptor for bovine papillomavirus type 4 (BPV-4), which is strictly epitheliotropic and infects the mucous epithelium of the upper digestive tract, was investigated....

Author(s)
Sibbet, G.; Romero-Graillet, C.; Meneguzzi, G.; Campo, M. S.
Citation
Journal of General Virology, 2000, 81, 2, pp 327-334
Abstract

In a review of non-viral bullous skin diseases of domestic animals and a 4-year study of cases presented to the New York State College of Veterinary Medicine, 15 diseases were found: pemphigus vulgaris, pemphigus vegetans, pemphigus foliaceus, pemphigus erythematosus, bullous pemphigoid, systemic...

Author(s)
Scott, D. W.; Wolfe, M. J.; Smith, C. A.; Lewis, R. M.
Citation
Veterinary Pathology, 1980, 17, 3, pp 257-281

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