Objective: To determine effects of sedation achieved by xylazine (XYL) or acepromazine (ACE) on cardiopulmonary function and uterine blood flow in cows in late gestation. Animals: 8 cows between 219 and 241 days of gestation. Procedure: Doses of ACE (0.02 mg/kg) or XYL (0.04 mg/kg) were...

The dog is a widely-used model for conducting metabolic studies. This is mainly due to its large size and its physiology which is relatively similar to that of humans. Here, we attempted to optimize a postprandial metabolic study protocol used in dogs. Following acclimatization, female mongrel dogs ...

After 14.5±4 min of acepromazine administration, the calves became ataxic and went into sternal recumbency in 21±4 min. There was good sedation without analgesia but swallowing reflex was not abolished. The animals were standing with ataxia after 46±5 min and completely recovered in 86±3 min. There ...

Rumenostomy may be performed for therapeutic and digestibility research purposes in bovines, small ruminants and camelids. Several studies requires rumenostomy in buffaloes in order to sample ruminal content for laboratorial assays. However, complications and outcome of rumenostomy was poorly...

A method for the confirmation of the tranquilisers azaperone and its metabolite azaperol, of chlorpromazine, propionylpromazine and acepromazine, haloperidol, xylazine and the β-blocker carazolol in porcine and bovine kidney with LC-MS/MS was developed. Various solvents and extraction techniques...

In this study, a novel generic hapten of phenothiazine drugs was synthesized by derivatization of 2-chlorophenothiazine with sodium bromoacetate. Then the hapten was coupled to bovine serum albumin for production of the monoclonal antibody. Results showed that the obtained monoclonal antibody...

Effects of 2 drugs commonly used for chemical restraint of cattle were evaluated in 18 healthy adult Jersey cows. Endoscopic evaluations were performed before and after administration of each drug. Responses to stimuli were evaluated by stimulating the epiglottis, left and right arytenoid...

A fast and simple liquid chromatography with tandem mass spectrometry method for detection and confirmation of tranquilizers (chlorpromazine, propionylpromazine, acepromazine, triflupromazine, promazine, azaperone and its metabolite, azaperol) and beta-blocker (carazolol) in porcine and bovine...

A large variety of drugs are administered to large and small animals by veterinary clinicians for sedation, anesthesia, muscle relaxation, and analgesia. The present paper reports a simple and rapid multi-residue detection and quantitation method for four chemically different drugs: medetomidine,...

Chapters are:- Development of multiple analytical systems for steroid residues (androgens, oestrogens and progestogens) in slaughter animals, by T. Corbaye et al. of Liege (in French, pp. 5-39); Development of confirmatory techniques for detecting residues of specific problem chemicals (stanozolol, ...