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Abstract

Objectives: Xanthine urolithiasis and asymptomatic xanthinuria have been diagnosed in Cavalier King Charles spaniel dogs suggesting that primary xanthinuria may be a breed-related disorder, although itsprevalence remains unclear. The hypothesis of this study was that asymptomatic xanthinuria is...

Author(s)
Jacinto, A. M. L.; Mellanby, R. J.; Chandler, M.; Bommer, N. X.; Carruthers, H.; Fairbanks, L. D.; Gow, A. G.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Small Animal Practice, 2013, 54, 8, pp 395-398
Abstract

It is assumed that Cavalier King Charles spaniels with Chiari-like malformation and syringomyelia experience central neuropathic pain. An association between spinal cord parenchymal lesions and specific clinical signs (e.g. spontaneous and evoked scratching, withdrawal, and paroxysmal pain...

Author(s)
Thoefner, M. S.; Westrup, U.; Toft, N.; Bjerrum, O. J.; Berendt, M.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Journal, 2019, 246, pp 92-97
Abstract

The onset of fear-related avoidance behavior occurs during and, to some extent, defines the sensitive period of development in the domestic dog. The objectives of this study were to identify the onset of fear-related avoidance behavior and examine breed differences in this behavioral development. A ...

Author(s)
Morrow, M.; Ottobre, J.; Ottobre, A.; Neville, P.; St-Pierre, N.; Dreschel, N.; Pate, J. L.
Publisher
Elsevier, New York, USA
Citation
Journal of Veterinary Behavior: Clinical Applications and Research, 2015, 10, 4, pp 286-294
Abstract

Premature closure of cranial base synchondroses has been proposed as the mechanism for brachycephaly in dogs and caudal occipital malformation syndrome (COMS) in Cavalier King Charles Spaniels. The purpose of this retrospective study was to compare times of closure for cranial base synchondroses in ...

Author(s)
Schmidt, M. J.; Volk, H.; Klingler, M.; Failing, K.; Kramer, M.; Ondreka, N.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Radiology & Ultrasound, 2013, 54, 5, pp 497-503
Abstract

Our aim was to determine the relative volume of the occipital bone of Cavalier King Charles spaniels with and without syringohydromyelia and normal French bulldogs to reappraise the role of a possible insufficiency of the paraxial mesoderm in the pathogenesis of the caudal occipital malformation...

Author(s)
Schmidt, M. J.; Kramer, M.; Ondreka, N.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Radiology & Ultrasound, 2012, 53, 5, pp 540-544
Abstract

Background: Chiari-like malformation in the Cavalier King Charles Spaniel is a herniation of the cerebellum and brainstem into or through the foramen magnum. This condition predisposes to Syringomyelia; fluid filled syrinxes within the spinal cord. The resulting pathology in spinal cord and...

Author(s)
Olsen, E.; Suiter, E. J.; Pfau, T.; McGonnell, I. M.; Matiasek, K.; Giejda, A.; Volk, H. A.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2017, 13, 159, pp (6 June 2017)
AbstractFull Text

Chiari-like malformation (CM) and Syringomyelia (SM) are complex neurological disorders, that affects the brain and respectively the spinal cord. These conditions affect certain toy breed dogs, among which the Cavalier King Charles Spaniel breed is overrepresented, causing numerous clinical signs,...

Author(s)
Cucos, C. A.; Barut, A.; Ionașcu, I.; Constantinescu, R.; Vlagioiu, C.
Publisher
University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania
Citation
Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine, 2018, 75, 1, pp 118-122
Abstract

Background: Syringomyelia (SM) is a debilitating condition in the cavalier King Charles spaniel (CKCS) that results in neuropathic pain and diminished quality of life. Von Frey aesthesiometry (VFA) is a method of mechanical quantitative sensory testing that provides an objective sensory threshold...

Author(s)
Hechler, A. C.; Hostnik, E. T.; Cook, L. B.; Cole, L. K.; Moore, S. A.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2020, 16, 94, pp (20 March 2020)
Abstract

Syringomyelia is a neurological disease characterized by a tubular cavitation of the spinal cord parenchyma. The tubular cavitation contains cerebrospinal fluid, extends over several segments and is most often found in the cervical cord. Syringomyelia is a rare disease in the dog, except in ...

Author(s)
Stigen, Ø.; Aas, R. A.
Publisher
Den Norske Veterinærforening, Oslo, Norway
Citation
Norsk Veterinærtidsskrift, 2006, 118, 3, pp 141-149
Abstract

Cavalier King Charles spaniels (CKCSs) show the earliest onset and the highest incidence of myxomatous mitral valve disease (MMVD). Previous studies have suggested a polygenic inheritance of the disease in this breed and revealed an association with regions on canine chromosomes 13 and 14....

Author(s)
Bionda, A.; Cortellari, M.; Bagardi, M.; Frattini, S.; Negro, A.; Locatelli, C.; Brambilla, P. G.; Crepaldi, P.
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2020, 10, 10,

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