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Abstract

The etiology of canine gallbladder mucocele (GBM) has not yet been identified. However, several studies have linked GBM in dogs to particular breeds (Shetland Sheepdogs are commonly implicated), concurrent endocrine disease (hyperadrenocorticism and/or hypothyroidism), and a mutation in the canine ...

Author(s)
Cullen, J. M.; Willson, C. J.; Minch, J. D.; Kimbrough, C. L.; Mealey, K. L.
Publisher
American Association of Veterinary Laboratory Diagnosticians, Davis, USA
Citation
Journal of Veterinary Diagnostic Investigation, 2014, 26, 3, pp 434-436
Abstract

A spayed, female Shetland sheepdog diagnosed with Hansen type II inter vertebral disc disease showed progressive ataxia and loss of bark. Superoxide dismutase (SOD) 1 mutation analysis confirmed homozygous mutation. The dog died from insufficient breathing on day 859, necropsy was carried out, and...

Author(s)
Goda, M.; Miya, Y.; Mie, K.; Chambers, J.; Uchida, K.; Akiyoshi, H.
Publisher
Japan Veterinary Medical Association, Tokyo, Japan
Citation
Journal of the Japan Veterinary Medical Association, 2019, 72, 1, pp 43-47
Abstract

To investigate the base deletion and frequency of the canine ATP binding cassette subfamily B member 1 (ABCB1) gene in Nanjing, China, genomic DNA was extracted from the blood or oral swab samples of 246 dogs from the Veterinary Teaching Hospital of Nanjing Agricultural University. The ABCB1 gene...

Author(s)
Mei XiaoTing; Yang DeJi; Yao DaWei
Publisher
Veterinary Solutions LLC, Apopka, USA
Citation
International Journal of Applied Research in Veterinary Medicine, 2019, 17, 2, pp 121-125
Abstract

Background: Here, we report on the occurrence of neural tube defects (NTDs) in four related Shetland sheepdog puppies. NTDs present as a range of congenital malformations affecting the spine, skull and associated structures. Despite the severity of these malformations and their relatively high...

Author(s)
Thomas, Z. M.; Podadera, J. M.; Donahoe, S. L.; Foo, T. S. Y.; Weerakoon, L.; Mazrier, H.
Publisher
Wiley, Melbourne, Australia
Citation
Australian Veterinary Journal, 2020, 98, 7, pp 312-318
Abstract

Background: Histiocytic sarcoma affecting the central nervous system (CNS HS) in dogs may present as primary or disseminated disease, often characterized by inflammation. Prognosis is poor, and imaging differentiation from other CNS tumors can be problematic. Objective: To characterize the...

Author(s)
Toyoda, I.; Vernau, W.; Sturges, B. K.; Vernau, K. M.; Rossmeisl, J.; Zimmerman, K.; Crowe, C. M.; Woolard, K.; Giuffrida, M.; Higgins, R. J.; Dickinson, P. J.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2020, 34, 2, pp 828-837
Abstract

Miniature Schnauzers are the first canine breed, in the United States, reported to suffer from primary hyperlipidemia, but this has yet to be documented in other regions. Using over 900 canine plasma samples collected from over seven different veterinary clinics across Japan, the aim of this study...

Author(s)
Mori, N.; Lee, P.; Muranaka, S.; Sagara, F.; Takemitsu, H.; Nishiyama, Y.; Yamamoto, I.; Yagishita, M.; Arai, T.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2010, 88, 3, pp 394-399
Abstract

Background: A mutation in the canine multidrug resistance MDR1 gene (also referred as ABCB1), encoding for the multidrug resistance (MDR) P-glycoprotein (P-gp) transponder, causes a pathological condition known as 'ivermectin toxicosis'. The causative mutation, known since 2001, has been described...

Author(s)
Marelli, S. P.; Polli, M.; Frattini, S.; Cortellari, M.; Rizzi, R.; Crepaldi, P.
Publisher
BMJ Publishing Group, London, UK
Citation
Veterinary Record Open, 2020, 7, e000375,
Abstract

Background: Several breeds have physiological peculiarities that induce variations in reference intervals (RIs) compared with the general canine population. Shetland sheepdogs (SSs) are reported to be more predisposed to different diseases (eg, hyperlipidemia, gallbladder mucocele, and...

Author(s)
Ruggerone, B.; Giraldi, M.; Paltrinieri, S.; Scarpa, P.
Publisher
Wiley, Boston, USA
Citation
Veterinary Clinical Pathology, 2018, 47, 4, pp 617-624
AbstractFull Text

Merle patterning in dogs, caused by the insertion of a short interspersed element (SINE) in the genetic structure of SILV gene, is characterized by patches of diluted pigment intermingled with normal melanin. Sequencing analyses of SINE element localized in the canine SILV gene discovered a...

Author(s)
Miluchová, M.; Gábor, M.; Trakovická, A.; Hanusová, J.; Zubrická, S.; Zubrický, P.
Publisher
Fakultet Veterinarske Medicine, Univerziteta u Beogradu, Beograd, Serbia
Citation
Acta Veterinaria (Beograd), 2015, 65, 2, pp 238-245
Abstract

Objective: The ABCB1 gene encodes P-glycoprotein (P-gp), a cellular membrane pump. One functional mutation that leads to expression of a less functional form of P-gp, ABCB1-1Δ, has been described in dogs. Individuals with this mutation can have severe adverse reactions to common veterinary...

Author(s)
Soussa, R. W.; Woodward, A.; Marty, M.; Cannon, C. M.
Publisher
Wiley, Melbourne, Australia
Citation
Australian Veterinary Journal, 2020, 98, 3, pp 79-83

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