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Abstract

Pure breed dogs of Western origin are increasingly more popular in China as is a need to differentiate breeds and individual dogs for personal and forensic reasons. Research on genetic diversities of the canine population in China is rarely conducted. In this study, genetic distributions and...

Author(s)
Wang MengLei; Jin XiaoYe; Xiong Xin; Yang JinLong; Li JianPing; Wang Qi; Zhu BoFeng; Deng YaJun
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2019, 46, 2, pp 1577-1584
Abstract

Background: Canine lumbosacral stenosis is defined as narrowing of the caudal lumbar and/or sacral vertebral canal. A risk factor for neurologic problems in many large sized breeds, lumbosacral stenosis can also cause early retirement in Labrador retriever military working dogs. Though vital for...

Author(s)
Meenakshi Mukherjee; Jones, J. C.; Yao JianBo
Publisher
BioMed Central Ltd, London, UK
Citation
Canine Genetics and Epidemiology, 2017, 4, 12, pp (23 October 2017)
Abstract

Two hip quality phenotypes - a hip-extended score assigned by a board certified radiologist and the PennHIP distraction index - were analyzed to estimate genetic parameters and to calculate estimated breeding values used for selecting replacement breeders. Radiographs obtained at 12-18 months of...

Author(s)
Leighton, E. A.; Holle, D.; Biery, D. N.; Gregor, T. P.; McDonald-Lynch, M. B.; Wallace, M. L.; Reagan, J. K.; Smith, G. K.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2019, 14, 2, pp e0212544
Abstract

Background: Canine atopic dermatitis (cAD) is one the most common and distressing skin disorders seen in dogs. It is characterized by dysfunction in the skin barrier, with a complex pathogenesis combining both genetic and environmental factors. Objectives: To evaluate associations between...

Author(s)
Harvey, N. D.; Shaw, S. C.; Craigon, P. J.; Blott, S. C.; England, G. C. W.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Dermatology, 2019, 30, 5, pp 396-e119
Abstract

Mast cell tumours are the most common type of skin cancer in dogs, representing a significant concern in canine health. The molecular pathogenesis is largely unknown, but breed-predisposition for mast cell tumour development suggests the involvement of inherited genetic risk factors in some breeds. ...

Author(s)
Biasoli, D.; Compston-Garnett, L.; Ricketts, S. L.; Birand, Z.; Courtay-Cahen, C.; Fineberg, E.; Arendt, M.; Boerkamp, K.; Melin, M.; Koltookian, M.; Murphy, S.; Rutteman, G.; Lindblad-Toh, K.; Starkey, M.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS Genetics, 2019, 15, 3, pp e1007967
Abstract

OBJECTIVE: To sequence exons and splice consensus sites of the dynactin subunit 1 (DCTN1) gene in Leonbergers and Labrador Retrievers with clinical laryngeal paralysis. ANIMALS: 5 unrelated Leonbergers with laryngeal paralysis, 2 clinically normal Leonbergers, 7 unrelated Labrador Retrievers with...

Author(s)
Holt, D. E.; Brown, D. C.; Henthorn, P. S.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2016, 77, 10, pp 1114-1120
Abstract

Background: Diabetes mellitus (DM) in dogs is a common endocrinopathy with a complex genetic architecture. Disease susceptibility in several breeds is associated with polymorphisms in immune response genes, but in the Labrador retriever breed, no genetic associations with DM have been identified. A ...

Author(s)
Davison, L. J.; Holder, A.; Catchpole, B.; O'Callaghan, C. A.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2017, 31, 2, pp 343-348
Abstract

Background: Labrador retrievers are reportedly predisposed to many disorders but accurate prevalence information relating to the general population are lacking. This study aimed to describe demography, mortality and commonly recorded diseases in Labrador retrievers under UK veterinary care....

Author(s)
McGreevy, P. D.; Wilson, B. J.; Mansfield, C. S.; Brodbelt, D. C.; Church, D. B.; Navneet Dhand; Magalhães, R. J. S.; O'Neill, D. G.
Publisher
BioMed Central Ltd, London, UK
Citation
Canine Genetics and Epidemiology, 2018, 5, 8, pp (22 October 2018)
AbstractFull Text

Aim: To establish reference values of vertebral heart score (VHS) in Indian Spitz, Labrador retriever, and Mongrel dogs; to assess applicability of VHS in these three dog breeds; to determine if breed, recumbency side, gender, body weight, and thoracic depth (TD) to thoracic width (TW) ratio has an ...

Author(s)
Deepti Bodh; Mozammel Hoque; Saxena, A. C.; Gugjoo, M. B.; Deepika Bist; Chaudhary, J. K.
Publisher
Veterinary World, Rajkot, India
Citation
Veterinary World, 2016, 9, 4, pp 371-376
Abstract

Background: Exercise-induced collapse (EIC) due to DNM1 mutation and rupture of the cranial cruciate ligament are both common syndromes in the Labrador retriever breed. A cohort of 313 Labradors was recruited based on their CCLR status and were subsequently genetically tested for EIC....

Author(s)
Ekenstedt, K. J.; Minor, K. M.; Rendahl, A. K.; Conzemius, M. G.
Publisher
BioMed Central Ltd, London, UK
Citation
Canine Genetics and Epidemiology, 2017, 4, 2, pp (2 February 2017)

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