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Abstract

Hereditary cataract is a common ocular disorder in the purebred dog population and is a leading cause of visual impairment and blindness in dogs. Despite this, little is known to date about the genetics underlying this condition. We have used a genome-wide association study and targeted...

Author(s)
Ricketts, S. L.; Pettitt, L.; McLaughlin, B.; Jenkins, C. A.; Mellersh, C. S.
Publisher
Springer, New York, USA
Citation
Mammalian Genome, 2015, 26, 5/6, pp 257-263
Abstract

Merle is a distinct coat color and pattern found in numerous species, including the domestic dog, characterized by patches of diluted eumelanin (black pigment) interspersed among areas of normal pigmentation. In dogs, this variegated pattern is caused by an insertion of a SINE element into the ...

Author(s)
Ballif, B. C.; Ramirez, C. J.; Carl, C. R.; Sundin, K.; Krug, M.; Zahand, A.; Shaffer, L. G.; Flores-Smith, H.
Publisher
S Karger AG, Basel, Switzerland
Citation
Cytogenetic and Genome Research, 2018, 156, 1, pp 22-34
Abstract

Background: P-glycoprotein is a multidrug resistance (MDR) transporter, a member of the ATP binding cassette (ABC) family and is highly expressed in capillary endothelial cells in the brain. Its physiological function is to protect the body from potentially toxic compounds. In certain dog breeds a...

Author(s)
Palócz, O.; Benedek-Major, K.; Csigó, B.; Csikó, G.
Publisher
Herman Ottó Institute Nonprofit Ltd., Budapest, Hungary
Citation
Magyar Állatorvosok Lapja, 2018, 140, 8, pp 495-500
AbstractFull Text

Merle patterning in dogs, caused by the insertion of a short interspersed element (SINE) in the genetic structure of SILV gene, is characterized by patches of diluted pigment intermingled with normal melanin. Sequencing analyses of SINE element localized in the canine SILV gene discovered a...

Author(s)
Miluchová, M.; Gábor, M.; Trakovická, A.; Hanusová, J.; Zubrická, S.; Zubrický, P.
Publisher
Fakultet Veterinarske Medicine, Univerziteta u Beogradu, Beograd, Serbia
Citation
Acta Veterinaria (Beograd), 2015, 65, 2, pp 238-245
Abstract

This publication is devoted to the results of histological changes in the intervertebral discs in chondrodystrophoid dogs. Computed tomography (CT) was used to diagnose intervertebral disc extrusion in 4 dogs (3 dachshunds and 1 Australian shepherd) aged 7 to 14 years old with symptoms of spinal...

Author(s)
Semenov, B.; Mikhailova, A.; Kuznetsova, T.; Gankina, Y.
Publisher
Sankt-Peterburgskaya gosudarstvennaya akademiya veterinarnoy meditsiny, St Petersburg, Russia
Citation
Mezhdunarodnyy vestnik veterinarii, 2019, No.1, pp 108-112
Abstract

Background: Achromatopsia is an autosomal recessive disease characterized by the loss of cone photoreceptor function that results in day-blindness, total colorblindness, and decreased central visual acuity. The most common causes for the disease are mutations in the CNGB3 gene, coding for the beta...

Author(s)
Yeh, C. Y.; Goldstein, O.; Kukekova, A. V.; Holley, D.; Knollinger, A. M.; Huson, H. J.; Pearce-Kelling, S. E.; Acland, G. M.; Komáromy, A. M.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genetics, 2013, 14, 27, pp (20 April 2013)
Abstract

In light of improving breeding advice, the frequency was estimated for all the disease-causing mutations that were known at the start of the study and that are potentially relevant for a group of dog breeds, which are relatively popular or in which the genetic diversity in Belgium is low to...

Author(s)
Beckers, E.; Poucke, M. van; Ronsyn, L.; Peelman, L.
Publisher
Faculty of Veterinary Medicine, University of Ghent, Merelbeke, Belgium
Citation
Vlaams Diergeneeskundig Tijdschrift, 2016, 85, 4, pp 175-184
Abstract

To date, a 4-bp deletion in the MDR1 gene has been detected in more than ten dog breeds, as well as in mixed breed dogs, in several countries, however information regarding this mutation in dogs from Brazil is lacking. For this reason, 103 Collies, 77 Border Collies, 76 Shetland Sheepdogs, 20 Old...

Author(s)
Monobe, M. M.; Araujo Junior, J. P.; Lunsford, K. V.; Silva, R. C.; Bulla, C.
Publisher
Dove Medical Press Ltd, Macclesfield, UK
Citation
Veterinary Medicine: Research and Reports, 2015, 6, pp 111-117
Abstract

Noise reactivity is a common problem for dogs and may progress to true phobia. Survey studies report that some type of noise reaction occurs in up to half of all pet dogs throughout their lifetimes, indicating that noise reactivity and/or phobia is a welfare issue. Familial aggregations of affected ...

Author(s)
Overall, K. L.; Dunham, A. E.; Juarbe-Diaz, S. V.
Publisher
Elsevier, New York, USA
Citation
Journal of Veterinary Behavior: Clinical Applications and Research, 2016, 16, pp 113-125
Abstract

Drawing on American Kennel Club (AKC) puppy registration numbers for approximately 82 varieties of pedigree dogs between 1926 and 2005, the current article analyses behavioural reports on 32,005 dogs of these varieties reported through the Canine Behavioural Assessment and Research Questionnaire...

Author(s)
Wilson, B.; Serpell, J.; Herzog, H.; McGreevy, P.
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2018, 8, 11, pp 197

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