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Abstract

In the present literature review, the mechanisms of xylitol toxicosis in dogs are summarized and discussed by the authors. Xylitol, which is now widely used as a sweetener in human nutrition, causes a severe, commonly life-threatening toxicosis in dogs, being an emerging issue in small animal...

Author(s)
Remport, Á.; Mátis, G.; Juhász, O.; Kerek, Á.; Neogrády, Z.
Publisher
Herman Ottó Institute Nonprofit Ltd., Budapest, Hungary
Citation
Magyar Állatorvosok Lapja, 2018, 140, 2, pp 109-117
AbstractFull Text

Xylitol is a sweetener found in a wide range of processed foods for humans. However, its consumption by dogs affects important metabolic and pathophysiological pathways. In this context, this study aimed to evaluate the knowledge of tutors about xylitol, its presence in different food products...

Author(s)
Santos, L. S. D. dos; Gasparini, N. de A.; Brogiato, R. N.; Chiarelli, T. de S.; Souza, V. C. M. de; Santos, J. P. F.
Publisher
Pubvet, Maringá, Brazil
Citation
PUBVET, 2022, 16, 6,
AbstractFull Text

An adult dog were evaluated for treatment loss of consciousness, convulsions, and severe tremors after ingestion of xylitol, a sugar alcohol used as a sweetener in various products. Clinical findings were noted as loss of consciousness, convulsions, and severe tremors, while physio-pathological...

Author(s)
Hatipoğlu, D.; Kahraman, O.
Publisher
Ilker Çamkerten, Aksaray, Turkey
Citation
Journal of Advances in VetBio Science and Techniques, 2021, 6, 2, pp 165-170
Abstract

Polyols, also known as sugar alcohols, are widely used in the formulation of tooth-friendly and reduced-calorie foods. Considering the significant health benefits of polyols in products formulated for human use, there is increased interest in evaluating potential uses in companion animal...

Author(s)
Eapen, A. K.; Cock, P. de; Crincoli, C. M.; Means, C.; Wismer, T.; Pappas, C.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Food and Chemical Toxicology, 2017, 105, pp 448-455
Abstract

Xylitol is used as a sugar substitute in food products. Dogs have been reported to experience lethal liver injury after accidental ingestion of xylitol. Because liver injury may be a serious consequence of canine immune-mediated reactions, antibodies produced against xylitol may attack the liver....

Author(s)
Imai, A.; Nishita, T.; Ichihara, N.; Shirota, K.; Orito, K.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Immunology and Immunopathology, 2012, 149, 1/2, pp 108-111
Abstract

A 2-year-old spayed female Great Pyrenees cross dog was presented following the consumption of pure xylitol sweetener. Blood tests revealed hepatocellular leakage and cholestasis, hyperlactatemia, thrombocytopenia, and prolonged prothrombin and activated partial thromboplastin times. Thoracic...

Author(s)
Chalifoux, N. V.; Carr, A. P.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Veterinary Journal, 2020, 61, 8, pp 865-870
Abstract

Xylitol ingestions in dogs may result in severe hypoglycemia followed by acute hepatic failure and associated coagulopathies. Aggressive treatment may be needed, but the prognosis is generally expected to be good for dogs developing uncomplicated hypoglycemia. Because of increased availability of ...

Author(s)
Murphy, L. A.; Dunayer, E. K.
Publisher
Saunders, An Imprint of Elsevier, Philadelphia, USA
Citation
Veterinary Clinics of North America, Small Animal Practice, 2018, 48, 6, pp 985-990
Abstract

This research aimed to develop in vitro methods to assess hazard of canine food ingredients. Canine hepatocytes were harvested and cell viability of clove-leaf oil (CLO), eugenol (EUG), lemongrass oil (LGO), guanosine monophosphate (GMP), inosine monophosphate (IMP), sorbose, ginger-root extract...

Author(s)
Zhang, L. W.; Koci, J.; Jeffery, B.; Riviere, J. E.; Monteiro-Riviere, N. A.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Food and Chemical Toxicology, 2015, 78, pp 105-115
Abstract

Xylitol is commonly used as sugar substitute in households. While it has numerous beneficial effects on human health, it is highly toxic to dogs. The goal of this study was to examine whether xylitol has similar deleterious effects, such as hypoglycaemia and acute hepatic failure, on cats. Our...

Author(s)
Jerzsele, Á.; Karancsi, Z.; Pászti-Gere, E.; Sterczer, Á.; Bersényi, A.; Fodor, K.; Szabó, D.; Vajdovich, P.
Publisher
Wiley, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2018, 41, 3, pp 409-414
Abstract

Objectives: To test the in vitro antimicrobial efficacy of a non-toxic emulsion of free fatty acids against clinically relevant canine and feline periodontopathogens Methods: Antimicrobial kill kinetics were established utilising an alamarBlue® viability assay against 10 species of canine and...

Author(s)
Laverty, G.; Gilmore, B. F.; Jones, D. S.; Coyle, L.; Folan, M.; Breathnach, R.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Small Animal Practice, 2015, 56, 4, pp 253-263

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